Research Subjects
Oral Functional Science
Department | Research Subjects |
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Oral Functional Anatomy |
○Lamellar structure of bone and cellular cementum ○Origin of cementoblasts ○Atrophy and regeneration of salivary glands ○Effects of liquid diet on salivary glands |
Oral Physiology |
○Neurophysiological study for the control mechanism of feeding behavior ○Study for the central mechanism of nausea and vomiting ○Electrophysiological study for the brain functions ○Brain mechanisms of taste sensation ○Study for taste palatability and aversion ○Central nervous system of anorexia nervosa |
Oral Functional Prosthodontics |
○Mechanical analysis on removable dentures and dental implants ○Examination of the relationship between occlusion and the gene ral health of the body ○Development of biomaterials (including dental implant) and investigation of tissue reaction ○Application of carbon nanomaterials for biomaterials ○Clinical study on the prognosis and effects of prosthodontic treatment |
Crown and Bridge Prosthodontics |
○Research on genesis of bruxism and development of effective treatment methods ○Clinical research on sleep apnea-hypopnea syndrome ○Research on genesis of persistent uncomfortable occlusion by using brain function analysis ○3D Printing Technology Applying for Medicine ○Development of Dental CAD/CAM System ○Clinical Researches in Maxillofacial Prosthetics ○Researches on Dental Materials |
Orthodontics |
○Research for matrix turnover mechanisms after mechanical stress ○Research for mastication and articulation in relation to malocclusions ○Research for genetic cause of malocclusions ○Study on orthodontic materials and engineering ○Craniofacial growth and developmental study ○Diagnosis and treatment plan for patients with craniofacial deformity ○Diagnosis and treatment plan for cleft lip and palate patients ○Diagnosis and treatment plan for the patients with congenital anomaly. ○Study on measurement of cranio-maxillo-facial morphology by 3D CG model ○Clinical study on central regulatory mechanism of feeding behavior |
Dentistry for Children and Disabled Person |
○Basic and clinical research on physiological and abnormal root resorption of deciduous tooth ○Analysis of adhesive structure of adhesive materials to tooth ○Analysis of effects to central nervous system by change of occlu sion or stress ○Cardiovascular and neuroendocrine responses of pediatric patients during stress induced by dental treatment ○Morphological and functional study of malocculusion in primary dentition ○Clinical study of heart rate variability for disabled patients under dental treatments |
Oral Health Science
Department | Research Subjects |
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Developmental Biology of Hard Tissue |
○Cell biology on the regulatory function of osteotropic factors ○Cell biological and genetic assessment for bone development and regeneration ○Morphological and molecular study on the cell structure and function of bone cells |
Oral Biochemistry and Molecular Biology |
○Molecular mechanisms of bone formation and resorption ○Biochemistry and molecular biology of oral tissue ○Regulation of gene expression |
Biomaterials and Bioengineering |
○Development of novel biomaterials ○Nano-interfacial control for functional reconstruction of biological hard tissues ○Translational research on dental materials and devices ○Application of nano-technology in the dental fields ○Establishment of material evaluation system using in vitro osseointegration model ○Basic research for the construction of in vitro oral tissues model |
Preventive Dentistry |
○Examination of the factors affecting functional recovery and prognosis in the patients with partial edentulism ○Oral care for perioperative patient ○Molecular biology in oral microorganisms ○Epidemiological Study for dental caries, periodontal disease and dry mouth |
Restorative Dentistry |
○Operative Dentistry ○Cariology ○Biocompatibility ○Nanotechnology for dentistry |
Periodontology and Endodontology |
○Etiology and development of periodontal disease ○New techniques of periodontal examination, diagnosis, prevention and treatment ○Development of periodontal regenerative therapy ○Improvement of endodontic therapy ○Periodontal destruction in endodontic, peridontic, and traumatic lesions ○Development of treatment of vertical root fracture |
Gerodontology |
○Impact of oral health care on autonomy in older adults ○Influence of oral health status on quality of life in older adults ○Relationship between nutrition and oral health in older adults ○Age-associated changes in masticatory system ○Prevention and treatment of oral disease in older adults ○Treatment and pathophysiology of oral psychosomatic disorders |
Oral Pathobiological Science
Department | Research Subjects |
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Vascular Biology and Molecular Pathology |
1) Abnormalities of tumor vascular endothelial cells and development of novel therapy 2) Blood vessels and inflammation 3) Endotheliopathy in COVID-19 4) Blood vessel regeneration 5) Association between RNA and cell oncogenesis 6) Development and application of oncolytic virus |
Oral Molecular Microbiology |
○Utilization of microbial sequences for novel gene-tuning system ○Development and application of HPV detection systems ○Recognition and removal of oral microbes by innate immunity ○Structures and biological activities of oral microbial molecular patterns ○Oral tolerance against oral bacteria |
Pharmacology |
○Nobel pharmacological effects of anti-osteoporotic drugs ○Nobel pharmacological effects of anti-virus drugs ○Investigation of biological markers for skeletal diseases ○Development of quantitative imaging system for pharmacology ○Interaction between osteoblast and osteoclast ○Effect of mechanical stress on bone-cells and periodontal cells |
Oral Diagnosis and Medicine |
○Molecular imaging of oral diseases ○Positron Emission Tomography (PET) for evaluation of chemoradiotherapy in oral cancer ○Hypoxia imaging, FMISO-PET to evaluate oral cancer ○PET for evaluation of osteomyelitis of the jaw ○Inflammatory cytokines in saliva and oral medicine diseases ○Pathogenic role of autoantibodies of mucous membrane pemphigoid ○Clinical study of Oral Candidiasis and innate immunity ○Angiogenesis from periodontal ligament fibroblasts ○Muscle pathology on masticatory muscles ○Prevention of MRONJ using platelet rich fibrin 〇Molecular biologic research in various diseases in oral medicine. 〇Molecular biology on effects of Japanese traditional medicine (Kanpo) |
Oral and Maxillofacial Surgery |
○Basic and clinical studies of oral cancer ○Study on comprehensive treatment of cleft lip and palate preventing maxillary growth impediment ○Study on dredging method as a conservative treatment for ameloblastoma ○Study on functional and morphological improvement of skeletal malocclusion ○Study on eating and swallowing function in the elderly and postoperative patients with oral cancer ○Study on alveolar augmentation for tooth transplantation and dental implant |
Oral Radiology |
○Study for radiological imaging diagnosis on oral and maxillofacial lesions ○Clinical study of radiotherapy for oral cancers ○Molecular biology of oral cancers ○Study for radiation protection |
Dental Anesthesiology |
○Experimental and clinical studies on stress reactions ○Studies on mechanism of pharmacological actions of anesthetics ○Studies on monitors used in general management during dental treatment ○Study on carediovascular and endocrine changes in dental surgery ○Study on effects of tringeminal stimulation on autonomic function ○Study on anesthetic management of dental treatment in persons with disabilities |
Section for Clinical Education
Research Subjects |
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○Physico-chemical and ultra-morphological study on adhesion between tooth substrates and dental restorative materials ○Research on General Dentistry ○Studies on under-graduate and post-graduate clinical training |
Section for International Affairs
Research Subjects |
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○Globalization in dentistry ○Clinical oral physiology ○Temporomandibular disorders ○Sensory-motor interaction in orofacial region |
Stomatognathics (Cooperation Chair)
Department | Research Subjects |
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Gnatho-occlusal Function |
○Clinical research on etiology, diagnosis and management of temporomandibular disorders ○Research on mascular activity and blood flow state of masticatory muscles ○Clinical research on Orofacial Pain |
Improvement of Gnatho-oral Function |
○Dental implants for dento-maxillary defect ○Bone augmentation for dental implants ○Selection and installation condition of implant bodies |
Gnathoformative Medicine |
○Study on comprehensive treatment of cleft lip and palate against maxillary growth impediment ○Molecular genetic study on cleft lip and palate ○Study on velopharyngeal function 〇Study on application to the palatal plate of the adhesive gels 〇Study on mouth guards |
Geriatric Oral Science(Collaborative Chair)
Research Subjects |
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○The role and application of nitric monoxide to periodontal tissues ○Pathological analysis and control of periodontal disease as a vascular disease |