{"id":166,"date":"2019-01-29T15:46:52","date_gmt":"2019-01-29T06:46:52","guid":{"rendered":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol-test\/?page_id=166"},"modified":"2019-05-15T14:47:21","modified_gmt":"2019-05-15T05:47:21","slug":"publications2015","status":"publish","type":"page","link":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/publications\/publications2015\/","title":{"rendered":"2015"},"content":{"rendered":"<h4><strong>\u7dcf\u8aac\u30fb\u8457\u66f8\uff08\u65e5\u672c\u8a9e\uff09<\/strong><\/h4>\n<ol>\n<li><span style=\"text-decoration: underline\">\u6a0b\u7530\u4eac\u5b50<\/span>\uff1a\u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a\u7de8\u96c6\uff0c\u65b0\u81e8\u5e8a\u816b\u760d\u5b66\uff0d\u304c\u3093\u85ac\u7269\u7642\u6cd5\u5c02\u9580\u533b\u306e\u305f\u3081\u306b\uff0d\uff0c\u201c\u8840\u7ba1\u65b0\u751f\u201d\uff0c\u5357\u6c5f\u5802\uff0c44-47, 2015\uff08\u5206\u62c5\u57f7\u7b46\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>, \u9593\u77f3\u5948\u6e56\uff0c\u6a0b\u7530\u6cf0\u6d69:\u816b\u760d\u8840\u7ba1\u306e\u7279\u6027\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u5c55\u671b, \u9ad8\u5009\u4f38\u5e78\uff0c\u4f50\u8c37\u79c0\u884c\uff0c\u5927\u5cf6\u6b63\u4f38\uff0c\u77e2\u91ce\u8056\u4e8c\u7de8\u3000\u5b9f\u9a13\u533b\u5b66\u5897\u520a\u300c\u304c\u3093\u5fae\u5c0f\u74b0\u5883\u3068\u6a19\u7684\u6cbb\u7642\u300d33(5)\uff0c134-138\uff0c2015<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u8107\u7530\u3000\u7a14\uff0c\u524d\u7530\u5065\u5eb7\uff0c\u4e2d\u6751\u6d69\u5f70\uff0c\u7db2\u585a\u61b2\u751f\u7de8\uff0c\u53e3\u8154\u7d44\u7e54\u30fb\u767a\u751f\u5b66\u3000\u7b2c2\u7248\uff0c\u201c\u764c\u3068\u8840\u7ba1\u65b0\u751f\u201d\uff0c\u533b\u6b6f\u85ac\u51fa\u7248\uff0c221-223\uff0c2015\uff08\u5206\u62c5\u57f7\u7b46\uff09<\/li>\n<\/ol>\n<h4><strong>\u82f1\u8a9e\u8ad6\u6587<\/strong><\/h4>\n<ol>\n<li>Yamada K.<strong>\u00a7<\/strong>, Maishi N.<strong>\u00a7<\/strong>, Akiyama K., Alam Mohammad Towfik, Ohga N., Kawamoto T., Shindoh M. Takahashi N., Kamiyama T., Hida Y., Taketomi A. and\u00a0<u>*Hida K<\/u>.\uff1aCXCL 12-CXCR7 axis is important for tumor endothelial cell angiogenic property,\u00a0<strong><em>Int J Cancer<\/em><\/strong>\u00a0137(12), 2825-2836 2015 (selected as a cover)<\/li>\n<li>Matsumoto R., Tsuda M., Wang L.; Maishi N., Abe T., Kimura T., Tanino M., Nishihara H.,\u00a0<u>Hida K.<\/u>, Ohba Y., Shinohara N., Nonomura K., Tanaka S.,\uff1aAdaptor protein CRK induces epithelial\u2013mesenchymal transition and metastasis of bladder cancer cells through HGF\/c-Met feedback loop,\u00a0<strong><em>Cancer Sci<\/em><\/strong>, 106(6), 709-717<\/li>\n<li>Akiyama K., Ohga N., Hida Y., Maishi N., Ohba Y., Alam MT., Kawamoto T., Ohmura H., Yamada K., Torii C., Shindoh M. and<u>\u00a0*Hida K<\/u>.\uff1aInhibition of multidrug transporter in tumor endothelial cells enhances antiangiogenic activity\uff0c<strong><em>Am J Pathol<\/em><\/strong>,185(2), 572-580, 2015<\/li>\n<\/ol>\n<h4><strong>\u62db\u5f85\u8b1b\u6f14<\/strong><\/h4>\n<ol>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c38\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u300c\u8840\u7ba1\uff65\u4ee3\u8b1d\u7570\u5e38\u306e\u52d5\u7684\u5909\u5316\u3092\u63a2\u308b\u30a8\u30d4\u30b2\u30ce\u30df\u30af\u30b9\u300d\uff0c\u201c\u816b\u760d\u8840\u7ba1\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u7570\u5e38\u3068\u30a8\u30d4\u30b2\u30ce\u30e0\u201d 2015.12.3\uff08\u795e\u6238\uff09<\/li>\n<li><u>Hida K<\/u>.\uff1aTumor Endothelial Cells as Key Players in Tumor Metastasis\uff0c2015 Asian-Australian Vascular Biology Meeting (AAVBM)\uff0c2015.10.15 (Busan, Korea)<\/li>\n<li><u>Hida K<\/u>.\uff1aTumor Endothelial Cells as Key Players in Tumor Metastasis\uff0cKAIST Vascular Biology Mini-Symposium 2015\uff0c2015.10.14 (Daejeon, Korea)<\/li>\n<li><u>Hida K<\/u>.\uff1aTumor endothelial cells and cancer progression\uff0c\u7b2c74\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff0c2015.10.10\uff08\u540d\u53e4\u5c4b\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c67\u56de\u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u907a\u4f1d\u5b50\u767a\u73fe\u5236\u5fa1\u306e\u7570\u5e38\u304c\u5c0e\u304f\u6052\u5e38\u6027\u7834\u7dbb\u3068\u75be\u60a3\u300d,\u201c\u816b\u760d\u8840\u7ba1\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u7570\u5e38\u3068\u304c\u3093\u306e\u60aa\u6027\u5316\u201d\uff0c2015.6.30\uff08\u6771\u4eac\uff09<\/li>\n<li>Maishi N.,\u00a0<u>Hida K<\/u>.\uff1aSpring Special Symposium of the Japanese Vascular Biology and Medicine Organization,\u201cTumor endothelial cells instigate metastasis of indolent tumors\u201d,2015.5.13\uff08Osaka, Japan\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c104\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u7dcf\u4f1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u660e\u65e5\u306e\u75c5\u7406\u5b66\u3092\u62d3\u304f 2\u65b0\u6280\u8853\u30fb\u65b0\u6982\u5ff5\u304c\u62d3\u304f\u6b21\u4e16\u4ee3\u75c5\u7406\u5b66\u300d\uff0c\u201c\u304c\u3093\u5fae\u5c0f\u74b0\u5883\u306b\u304a\u3051\u308b\u8840\u7ba1\u306e\u7279\u7570\u6027\u201d, 2015.5.1\uff08\u540d\u53e4\u5c4b\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c33\u56de \u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\uff65\u5b66\u8853\u5927\u4f1a,\u201c\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306e\u304c\u3093\u8ee2\u79fb\u4fc3\u9032\u6a5f\u69cb\u201d\uff0c2015.1.30\uff08\u5948\u826f\uff09<\/li>\n<\/ol>\n<h4>\u56fd\u969b\u5b66\u4f1a\u767a\u8868<\/h4>\n<ol>\n<li><u>Hida K<\/u>.\uff1aTumor Endothelial Cells as Key Players in Tumor Metastasis\uff0c2015 Asian-Australian Vascular Biology Meeting (AAVBM)\uff0c2015.10.15, Busan, Korea<\/li>\n<li><u>Hida K<\/u>.\uff1aTumor Endothelial Cells as Key Players in Tumor Metastasis\uff0cKAIST Vascular Biology Mini-Symposium 2015\uff0c2015.10.14, Daejeon, Korea<\/li>\n<li>Maishi N., Ohba Y., Akiyama K., Ohga N., Hamada J., Mohammad Towfik Alam, Shindoh M., Hida Y.,\u00a0<u>Hida K<\/u>\uff1aTumor endothelial cells promote metastasis via biglycan secretion\uff0cThe European Cancer Congress 2015, 2015.9.27 (Vienna, Austria)<\/li>\n<\/ol>\n<h4><strong>\u56fd\u5185\u5b66\u4f1a\u767a\u8868<\/strong><\/h4>\n<ol>\n<li>\u9593\u77f3\u5948\u6e56, \u5927\u5834\u96c4\u4ecb, \u79cb\u5c71\u5ee3\u8f14, \u5927\u8cc0\u5247\u5b5d, \u6d5c\u7530\u6df3\u4e00, \u5317\u672c\u5b97\u5b50, Mohammad Alam T., \u5c71\u672c\u548c\u5e78, \u5ddd\u672c\u6cf0\u8f14, \u4e95\u4e0a\u8fb2\u592b\u7537, \u6b66\u5bcc\u7d39\u4fe1, \u9032\u85e4\u6b63\u4fe1, \u6a0b\u7530\u6cf0\u6d69, <u>\u6a0b\u7530\u4eac\u5b50<\/u>. \u201c\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u3088\u308bbiglycan \u306e\u5206\u6ccc\u3092\u4ecb\u3057\u305f\u304c\u3093\u306e\u8ee2\u79fb\u4fc3\u9032.\u201d \u7b2c23\u56de\u65e5\u672c\u8840\u7ba1\u751f\u7269\u533b\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, 2015.12.11\uff08\u795e\u6238\uff09<\/li>\n<li>\u5317\u689d\u656c\u4e4b\uff0c\u9593\u77f3\u5948\u6e56\uff0cMohammad T Alam\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u85e4\u6fa4\u4fca\u660e\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1aROS \u306b\u3088\u308bbiglycan \u767a\u73fe\u8a98\u5c0e\u3092\u4ecb\u3057\u305f\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u8840\u7ba1\u65b0\u751f\u80fd\u4ea2\u9032\uff0c\u7b2c74\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff0c2015.10.10\uff08\u540d\u53e4\u5c4b\uff09<\/li>\n<li>\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5ddd\u672c\u6cf0\u8f14\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u912d\u6f22\u5fe0\uff0c\u6238\u585a\u9756\u5247\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u5357\u656c\uff0c\u5c0f\u5742\u5c55\u6176\uff0c\u843d\u8c37\u5b5d\u5e83\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u9ad8\u8ee2\u79fb\u6027\u816b\u760dmiRNA \u306fIL-6 \u306a\u3089\u3073\u306bALDH \u306e\u767a\u73fe\u4ea2\u9032\u3092\u4ecb\u3057\u3066\u8840\u7ba1\u5185\u76ae\u306b\u85ac\u5264\u8010\u6027\u3092\u8a98\u5c0e\u3059\u308b\uff0c\u7b2c74\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff0c2015.10.10\uff08\u540d\u53e4\u5c4b\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff0c\u5927\u5834\u96c4\u4ecb\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u6d5c\u7530\u6df3\u4e00\uff0c\u5317\u672c(\u6c38\u5c3e\uff09\u5b97\u5b50\uff0cMohammad Alam T.\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306fbiglycan \u306e\u5206\u6ccc\u3092\u4ecb\u3057\u3066\u304c\u3093\u306e\u8ee2\u79fb\u3092\u4fc3\u9032\u3059\u308b\uff0c\u7b2c74\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff0c2015.10.8\uff08\u540d\u53e4\u5c4b\uff09<\/li>\n<li>Annan Dorcas A., \u9593\u77f3\u5948\u6e56\uff0c\u5317\u689d\u656c\u4e4b\uff0c\u9ce5\u5c45\u3061\u3055\u307b\uff0cMohammad T Alam.\uff0cHabiba Umma\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1aTumor Endothelial cell-secreted protein activates a DNA damage response\uff0c\u7b2c112\u56de\u5317\u6d77\u9053\u764c\u8ac7\u8a71\u4f1a\u4f8b\u4f1a\uff0c2015.9.12\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5ddd\u672c\u6cf0\u8f14\uff0c\u9593\u77f3\u5948\u6e56\uff0cAlam Mohammad Towfik\uff0c\u912d\u3000\u6f22\u5fe0\uff0c\u6238\u585a\u9756\u5247\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u5357\u3000\u656c\uff0c\u5c0f\u5742\u5c55\u6176\uff0c\u843d\u8c37\u5b5d\u5e83\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u9ad8\u8ee2\u79fb\u6027\u816b\u760dmiR\u306b\u3088\u3089\u3046\u8840\u7ba1\u5185\u76ae\u306b\u304a\u3051\u308bIL-6\u3092\u4ecb\u3057\u305f\u85ac\u5264\u8010\u6027\u8a98\u5c0e\uff0c\u7b2c112\u56de\u5317\u6d77\u9053\u764c\u8ac7\u8a71\u4f1a\u4f8b\u4f1a\uff0c2015.9.12\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff0c\u5927\u5834\u96c4\u4ecb\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u6d5c\u7530\u6df3\u4e00\uff0c\u5317\u672c\u5b97\u5b50\uff0cAlam Mohammad Towfik\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306fbiglycan\u306e\u5206\u6ccc\u3092\u4ecb\u3057\u3066\u304c\u3093\u306e\u8ee2\u79fb\u3092\u4fc3\u9032\u3059\u308b\uff0c\u7b2c26\u56de\u65e5\u672c\u81e8\u5e8a\u53e3\u8154\u75c5\u7406\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff0c2015.7.31\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5ddd\u672c\u6cf0\u8f14\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u912d\u3000\u6f22\u5fe0\uff0c\u6238\u585a\u9756\u5247\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u9ad8\u8ee2\u79fb\u6027\u816b\u760dmiRNA\u306fIL-6\u306a\u3089\u3073\u306bALDH\u306e\u767a\u73fe\u4ea2\u9032\u3092\u4ecb\u3057\u3066\u8840\u7ba1\u5185\u76ae\u306b\u85ac\u5264\u8010\u6027\u3092\u8a98\u5c0e\u3059\u308b\uff0c\u7b2c26\u56de\u65e5\u672c\u81e8\u5e8a\u53e3\u8154\u75c5\u7406\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff0c2015.7.31\uff08\u672d\u5e4c\uff09<\/li>\n<li>Alam Mohammad Towfik\uff0cNagao-Kitamoto H., Ohga N., Akiyama K., Maishi N., Shinohara N., Taketomi A. Shindoh M., Hida Y.,\u00a0<u>Hida K<\/u>.\uff1aSuprabasin as a novel tumor endothelial cell 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