{"id":163,"date":"2019-01-29T15:44:47","date_gmt":"2019-01-29T06:44:47","guid":{"rendered":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol-test\/?page_id=163"},"modified":"2019-05-15T14:48:06","modified_gmt":"2019-05-15T05:48:06","slug":"publications2016","status":"publish","type":"page","link":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/publications\/publications2016\/","title":{"rendered":"2016"},"content":{"rendered":"<h4>\u7dcf\u8aac\u30fb\u8457\u66f8\uff08\u65e5\u672c\u8a9e\uff09<\/h4>\n<ol>\n<li><span style=\"text-decoration: underline\">Hida K.<\/span>, Maishi N., Dorcas Akuba-Muhyia Annan and Hida Y.\uff1aEdit by Takanori Kawaguchi, Cancer Metastasis and Cancer Stem Cell\/Niche, \u201cTumor Endthelial Cells and Cancer Progression\u201d, Bentham Books, 61-73, 2016\uff08\u5206\u62c5\u57f7\u7b46\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u816b\u760d\u8840\u7ba1\u30fb\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u7279\u5fb4\u3068\u305d\u306e\u5206\u5b50\u6a5f\u69cb\uff0c\u533b\u5b66\u306e\u3042\u3086\u307f\u201c\u304c\u3093\u5fae\u5c11\u74b0\u5883\u306e\u75c5\u614b\u7406\u89e3\u3068\u5236\u5fa1\u201d\uff0c258(1)\uff0c11-14\uff0c2016<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u30de\u30a4\u30af\u30edRNA\u3068\u8840\u7ba1\u75be\u60a3\uff0c\u300c\u8840\u7ba1\u533b\u5b66\uff1a\u4eca\u304c\u65ec\uff01\u30de\u30a4\u30af\u30edRNA\u30fb\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u6700\u524d\u7dda\u300d\uff0c17(1)\uff0c71-76\uff0c2016<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u6a0b\u7530\u6cf0\u6d69\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u591a\u69d8\u6027\uff0c\u5225\u518aBIO Clinica \u6162\u6027\u708e\u75c7\u3068\u75be\u60a3\uff5e\u6162\u6027\u708e\u75c7\u3068\u304c\u3093\uff0c5(1)\uff0c\u5317\u9686\u9928\uff0c158-164\uff0c2016<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff0c\u9593\u77f3\u5948\u6e56\uff1a\u816b\u760d\u8840\u7ba1\u306e\u5206\u5b50\u751f\u7269\u5b66\u7684\u7279\u5fb4\uff0c\u300c\u7d30\u80de\u5de5\u5b66\uff5e\u7279\u96c6\u3000\u6297\u816b\u760d\u8840\u7ba1\u65b0\u751f\u7642\u6cd5\u306e\u65b0\u5c55\u958b\u300d35(1)\uff0c19-22\uff0c2016<\/li>\n<\/ol>\n<h4>\u82f1\u6587\u7dcf\u8aac<\/h4>\n<ol>\n<li><u>*Hida K<\/u>., Maishi N., Torii C., Hida Y.\uff1aTumor Angiogenesis\u2014Characteristics of Tumor Endothelial Cells,\u00a0<strong><em>Int J Clin Oncol,\u00a0<\/em><\/strong>21(2),206-212<\/li>\n<li><u>*Hida K<\/u>., Maishi N., Sakurai Y., Hida Y., Harashima H.\uff1aHeterogeneity of tumor endothelial cells and drug delivery,\u00a0<strong><em>Adv Drug Deliv Rev<\/em><\/strong><strong><em>,\u00a0<\/em><\/strong>99(Pt B), 140-147, 2016<\/li>\n<\/ol>\n<h4><strong>\u82f1\u8a9e\u8ad6\u6587<\/strong><\/h4>\n<ol>\n<li><u>*Hida K<\/u>., Maishi N., Kawamoto T., Akiyama K., Ohga N., Hida Y., Yamada K., Hojo T., Kikuchi H., Sato M., Torii C., Shinohara N., Shindoh M.\uff1aTumor endothelial cells express high pentraxin 3 levels,\u00a0<strong><em>Pathol Int<\/em><\/strong>, 66(12), 687-694,2016<\/li>\n<li><u>*Hida K<\/u>., Maishi N., Torii C., Yanagiya M., Annan Akuba-Muhyia Dorcas., Morimoto M.,\u00a0<a href=\"http:\/\/www.den.hokudai.ac.jp\/vascular-biology\/members-towfik.html\">Alam Mohammad Towfik<\/a>\uff1aComparison of characteristics of mouse immortalized normal endothelial cells, MS1 and primary cultured endothelial cells,\u00a0<strong><em>Hokkaido Journal of Dental Science<\/em><\/strong>, 37(1), 40-48, 2016<\/li>\n<li>Maishi N., Ohba Y., Akiyama K., Ohga N., Hamada J., Nagao-Kitamoto H., Mohammad Towfik Alam, Yamamoto K., Kawamoto T., Inoue N., Taketomi A., Shindoh M., Hida Y.,\u00a0<u>*Hida K<\/u>.\uff1aTumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan,\u00a0<strong><em>Sci Rep<\/em><\/strong>, 6, 28039<strong><a href=\"http:\/\/www.readcube.com\/articles\/10.1038\/srep28039\">\u3014PDF\u3015<\/a><\/strong><\/li>\n<li>Shahrabi-Farahani S., Gallottini M., Martins F., Li E., Mudge DR., Nakayama H.,\u00a0<u>Hida K.<\/u>, Panigrahy D., D\u2019Amore PA., Bielenberg DR.\uff1a Neuropilin 1 Receptor is Upregulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma,\u00a0<strong><em>Am J Pathol,<\/em><\/strong>\u00a0186(4), 1055-1064, 2016<\/li>\n<\/ol>\n<h4><strong>\u62db\u5f85\u8b1b\u6f14<\/strong><\/h4>\n<ol>\n<li>\u9593\u77f3\u5948\u6e56\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c75\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\u7279\u5225\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff12\u300c\u764c\u7814\u7a76\u306b\u304a\u3051\u308b\u5973\u6027\u7814\u7a76\u8005\u300d\uff0c\u201c\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u3088\u308b\u304c\u3093\u8ee2\u79fb\u4fc3\u9032\u201d\uff0c2016.10.7\uff08\u6a2a\u6d5c\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c53\u56de\u5927\u962a\u5927\u5b66\u6570\u7406\u533b\u5b66\u7814\u7a76\u4f1a\uff0c\u201c\u816b\u760d\u8840\u7ba1\u306e\u7279\u6027\u89e3\u660e\u3068\u65b0\u3057\u3044\u304c\u3093\u6cbb\u7642\u6226\u7565\u201d\uff0c2016.9.28\uff08\u5927\u962a\u5e9c\u8c4a\u4e2d\u5e02\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u5343\u91cc\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u30bb\u30df\u30ca\u30fcK3\u300c\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u7814\u7a76\u306e\u6700\u524d\u7dda\uff1a\u75be\u60a3\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u89e3\u660e\u304b\u3089\u8a3a\u65ad\u30fb\u6cbb\u7642\u307e\u3067\u300d\uff0c\u201c\u816b\u760d\u8840\u7ba1\u306e\u7279\u7570\u6027\u3068\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u201d\uff0c2016.9.16\uff08\u5927\u962a\u5e9c\u8c4a\u4e2d\u5e02\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff0c\u9593\u77f3\u5948\u6e56\uff1a\u7b2c58\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u300cA New Horizon for Oral Health Science\uff5e\u4e16\u754c\u306b\u98db\u8e8d\u3059\u308b\u30aa\u30fc\u30e9\u30eb\u30d8\u30eb\u30b9\u30b5\u30a4\u30a8\u30f3\u30b9\u306e\u6700\u524d\u7dda\uff5e\u300d\uff0c\u201c\u304c\u3093\u5fae\u5c11\u74b0\u5883\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u7279\u7570\u6027\u89e3\u660e\u3068\u305d\u306e\u5206\u5b50\u6a5f\u69cb\u201d\uff0c8.24\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u9593\u77f3 \u5948\u6e56\u3001<u>\u6a0b\u7530<\/u><u>\u00a0<\/u><u>\u4eac\u5b50<\/u>\uff1a\u7b2c 69 \u56de\u65e5\u672c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3068\u767a\u304c\u3093\uff5e\u6700\u65b0\u306e\u77e5\u898b\uff5e\u300d\uff64\u201c\u6d3b\u6027\u9178\u7d20\u304c\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u53ca\u307c\u3059\u5f71\u97ff\u201d\uff0c2016.8.31\uff08\u4ed9\u53f0\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff0c\u9593\u77f3\u5948\u6e56\uff1a\u7b2c25\u56de\u65e5\u672c\u304c\u3093\u8ee2\u79fb\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7dcf\u4f1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300c\u304c\u3093\u8ee2\u79fb\u306e\u65b0\u3057\u3044\u6cbb\u7642\u6a19\u7684\u3068\u3057\u3066\u306e\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u7814\u7a76\u300d\uff0c\u201c\u9ad8\u8ee2\u79fb\u6027\u816b\u760dmiR\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u306b\u304a\u3051\u308b\u85ac\u5264\u8010\u6027\u8a98\u5c0e\u201d\uff0c2016.7.21\uff08\u7c73\u5b50\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u3088\u308b\u304c\u3093\u8ee2\u79fb\u4fc3\u9032\uff0c\u7b2c12\u56de\u5317\u6d77\u9053\u764c\u514d\u75ab\u5236\u5fa1\u7814\u7a76\u4f1a\uff0c2016.7.9\uff08\u672d\u5e4c\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c70\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u300c\u53e3\u8154\u75be\u60a3\u6cbb\u7642\u306e\u79d1\u5b66\u9769\u547d\uff08\u30d1\u30e9\u30c0\u30a4\u30e0\u30b7\u30d5\u30c8\uff09\u300d\u6307\u540d\u5831\u544a,\u3000\u6f14\u984c\uff1a \u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u7279\u7570\u6027\u89e3\u660e\u3068\u65b0\u305f\u306a\u304c\u3093\u6cbb\u7642\u3078\u306e\u5fdc\u7528, 2016.4.17\uff08\u798f\u5ca1\uff09<\/li>\n<li><u>Hida K<\/u>.\uff1aHeterogeneity of Tumor Endothelial Cells, Keystone Symposia on Molecular and Cellular Biology, 2016, 2016.4.1, Breckenridge, Colorado.<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\u3001\u9593\u77f3\u5948\u6e56\u3001\u6a0b\u7530\u6cf0\u6d69\uff1a\u5e73\u621027\u5e74\u5ea6\u300c\u500b\u4f53\u30ec\u30d9\u30eb\u3067\u306e\u304c\u3093\u7814\u7a76\u652f\u63f4\u6d3b\u52d5\u300d\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\uff0c\u201c\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u7279\u6027\u3068\u304c\u3093\u306e\u60aa\u6027\u5316\u201d2015.2.3\uff08\u5927\u6d25\uff09<\/li>\n<li><u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u7b2c34\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u300c\u53e3\u8154\u304c\u3093\u306e\u6b21\u4e16\u4ee3\u6cbb\u7642\u3092\u76ee\u6307\u3057\u305f\u5148\u7aef\u7684\u7814\u7a76\u300d\u201c\u816b\u760d\u8840\u7ba1\u306e\u7570\u5e38\u3068\u304c\u3093\u306e\u60aa\u6027\u5316\u201d2016. 1. 21 (\u6a2a\u6d5c)<\/li>\n<\/ol>\n<h4><strong>\u56fd\u969b\u5b66\u4f1a\u767a\u8868<\/strong><\/h4>\n<ol>\n<li><u>Hida K.<\/u>, Torii C., Maishi N., Morimoto M., Akiyama K., Kawamoto T., Minami T.,\u00a0 Yoshioka Y., Mohammad Towfik Alam, \u00a0Shindoh M., Hida Y., Ochiya T\uff1aTumor endothelial cells acquire drug resistance by exosomal-miR derived from high metastatic tumor, The 19th International Vascular Biology Meeting, 2016. 11.2, Boston, Massachusetts, USA<\/li>\n<li>Maishi N., Ohba Y., Akiyama K., Ohga N., Hamada J., Nagao-Kitamoto H., Mohammad Towfik Alam, Shindoh M., Hida Y.\u00a0<u>Hida K<\/u>.\uff1aTumor endothelial cells in high metastatic tumors promote metastasis via biglycan, The 19th International Vascular Biology Meeting, 2016. 11.2, Boston, Massachusetts, USA<\/li>\n<li>Kikuchi H., Maishi N., Akiyama K., Morimoto M., Yanagiya M., Miyajima N., Tuchiya K., Maruyama S., Abe T., Hida Y., Harabayashi T., Ameda K., Matsumoto R., Kashiwagi A., Demura T., Tsuda M., Tanaka S., Matsuno Y., Shinohara N.,\u00a0<u>Hida K<\/u>.\uff1aP-glycoprotein expression dynamics in tumor blood vessels of urothelial carcinoma during chemotherapy,\u201d has been accepted for presentation at Vascular Biology, The 19th International Vascular Biology Meeting, 2016. 11.2, Boston, Massachusetts, USA<\/li>\n<li><u>Hida K<\/u>., Maishi N., Ohga N., Hida Y.\uff1aHeterogeneity of Tumor endothelium, The 41th Naito Conference on \u201cCancer Heterogeneity and Plasticity: Relevance to Therapeutic Resistance\u201d, 2016.7.7 (Sapporo, Japan)<\/li>\n<li><u>Hida K<\/u>.\uff1aHeterogeneity of Tumor Endothelial Cells, Keystone Symposia on Molecular and Cellular Biology, 2016, 2016.4.1, Breckenridge, Colorado.<\/li>\n<li>Maishi N.\uff1aTumor Endothelial Cells Promote Metastasis via Biglycan, Keystone Symposia on Molecular and Cellular Biology, 2016, 2016.4.1, Breckenridge, Colorado.<\/li>\n<li>Maishi N., Ohba Y., Akiyama K., Ohga N., Hamada J., Mohammad Towfik Alam, Shindoh M., Hida Y.,\u00a0<u>Hida K<\/u>\uff1aTumor endothelial cells promote metastasis via biglycan secretion\uff0cTenth AACR-JCA Joint Conference \u201cBreakthroughs in Cancer Research: From Biology to Therapeutics\u201d,2016.2.17 (Maui,Hawaii)<\/li>\n<\/ol>\n<h4><strong>\u56fd\u5185\u5b66\u4f1a\u767a\u8868<\/strong><\/h4>\n<ol>\n<li>\u67f3\u8c37\u7f8e\u6c99\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u912d\u3000\u6f22\u5fe0\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u5317\u5ddd\u5584\u653f\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1aCorrelation between CXCR7 expression of blood vessels and clinicopathological features in oral squamous cell carcinoma\uff0c\u7b2c24\u56de\u65e5\u672c\u8840\u7ba1\u751f\u7269\u533b\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff0c2016.12.10\uff08\u9577\u5d0e\uff09<\/li>\n<li>\u83ca\u5730\u3000\u592e\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u68ee\u672c\u771f\u5f18\uff0c\u67f3\u8c37\u7f8e\u6c99\uff0c\u571f\u5c4b\u90a6\u5f66\uff0c\u5b89\u90e8\u5d07\u91cd\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u539f\u6797\u3000\u900f\uff0c\u98f4\u7530\u3000\u8981\uff0c\u67cf\u6728\u3000\u660e\uff0c\u7530\u4e2d\u4f38\u54c9\uff0c\u677e\u91ce\u5409\u5b8f\uff0c\u7be0\u539f\u4fe1\u96c4\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1aP-glycoprotein expression dynamics in tumor blood vessels of urothelial carcinoma during chemotherapy,\u7b2c24\u56de\u65e5\u672c\u8840\u7ba1\u751f\u7269\u533b\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff0c2016.12.10\uff08\u9577\u5d0e\uff09<\/li>\n<li>\u67f3\u8c37\u7f8e\u6c99\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u912d\u3000\u6f22\u5fe0\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u5317\u5ddd\u5584\u653f\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u30de\u30fc\u30ab\u30fcCXCR7\u306e\u767a\u73fe\u89e3\u6790\uff0c\u7b2c49\u56de\u5317\u6d77\u9053\u75c5\u7406\u8ac7\u8a71\u4f1a\uff0c\u7b2c7\u56deIGM\u7814\u7a76\u4ea4\u6d41\u4f1a\uff0c2016.10.18\uff08\u672d\u5e4c\uff09<\/li>\n<li>Annan Dorcas Akuba Muhyia\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u66fd\u6211\u670b\u7fa9\uff0c\u5317\u689d\u656c\u4e4b\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u83ca\u5730\u3000\u592e\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1aTumor endothelial cells are resistant to acidic environments\uff0c\u7b2c49\u56de\u5317\u6d77\u9053\u75c5\u7406\u8ac7\u8a71\u4f1a\uff0c\u7b2c7\u56deIGM\u7814\u7a76\u4ea4\u6d41\u4f1a\uff0c2016.10.18\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u83ca\u5730\u3000\u592e\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u571f\u5c4b\u90a6\u5f66\uff0c\u4e38\u5c71\u3000\u899a\uff0c\u5b89\u90e8\u5d07\u91cd\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u539f\u6797\u3000\u900f\uff0c\u677e\u91ce\u5409\u5b8f\uff0c\u7be0\u539f\u4fe1\u96c4\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u6297\u764c\u5264\u6cbb\u7642\u524d\u5f8c\u306e\u5c3f\u8def\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306eP-glycoprotein \u767a\u73fe\u5909\u5316\uff0c\u7b2c7\u56deIGM\u7814\u7a76\u4ea4\u6d41\u4f1a\uff0c2016.10.18\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u68ee\u672c\u771f\u5f18, \u9ce5\u5c45\u3061\u3055\u307b, \u5ddd\u672c\u6cf0\u8f14, \u79cb\u5c71\u5ee3\u8f14, \u9593\u77f3\u5948\u6e56, \u5409\u5ca1\u7950\u4eae, \u843d\u8c37\u5b5d\u5e83, \u67f3\u8c37\u7f8e\u6c99, \u83ca\u5730\u3000\u592e, \u5317\u5ddd\u5584\u653f, \u912d\u6f22\u3000\u5fe0, \u9032\u85e4\u6b63\u4fe1, \u6a0b\u7530\u6cf0\u6d69,\u00a0<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u9ad8\u8ee2\u79fb\u6027\u816b\u760d\u30a8\u30af\u30bd\u30bd\u30fc\u30e0miRNA\u306f\u8840\u7ba1\u5185\u76ae\u306eIL6\u3092\u8a98\u5c0e\u3057\u8840\u7ba1\u65b0\u751f\u963b\u5bb3\u7642\u6cd5\u3078\u306e\u8010\u6027\u3092\u8a98\u5c0e\u3059\u308b\uff0c\u7b2c7\u56deIGM\u7814\u7a76\u4ea4\u6d41\u4f1a\uff0c2016.10.18\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u67f3\u8c37\u7f8e\u6c99\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u912d\u3000\u6f22\u5fe0\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u5317\u5ddd\u5584\u653f\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u30de\u30fc\u30ab\u30fcCXCR7\u306e\u767a\u73fe\u89e3\u6790\uff0c\u7b2c49\u56de\u5317\u6d77\u9053\u75c5\u7406\u8ac7\u8a71\u4f1a\uff0c2016.10.15\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u83ca\u5730\u3000\u592e\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u68ee\u672c\u771f\u5f18\uff0c\u67f3\u8c37\u7f8e\u6c99\uff0c\u5bae\u5cf6\u76f4\u4eba\uff0c\u571f\u5c4b\u90a6\u5f66\uff0c\u4e38\u5c71\u3000\u899a\uff0c\u5b89\u90e8\u5d07\u91cd\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u539f\u6797\u3000\u900f\uff0c\u98f4\u7530\u3000\u8981\uff0c\u677e\u672c\u9686\u5150\uff0c\u67cf\u6728\u3000\u660e\uff0c\u51fa\u6751\u5b5d\u7fa9\uff0c\u6d25\u7530\u771f\u5bff\u7f8e\uff0c\u7530\u4e2d\u4f38\u54c9\uff0c\u677e\u91ce\u5409\u5b8f\uff0c\u7be0\u539f\u4fe1\u96c4\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u6297\u764c\u5264\u6cbb\u7642\u524d\u5f8c\u306e\u5c3f\u8def\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306eP-glycoprotein\u767a\u73fe\u5909\u5316\uff0c\u7b2c49\u56de\u5317\u6d77\u9053\u75c5\u7406\u8ac7\u8a71\u4f1a\uff0c2016.10.15\uff08\u672d\u5e4c\uff09<\/li>\n<li>Annan Dorcas Akuba Muhyia\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u66fd\u6211\u670b\u7fa9\uff0c\u5317\u689d\u656c\u4e4b\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u83ca\u5730\u3000\u592e\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1aTumor endothelial cells are resistant to acidic environments\uff0c\u7b2c49\u56de\u5317\u6d77\u9053\u75c5\u7406\u8ac7\u8a71\u4f1a\uff0c2016.10.15\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff0c\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u5ddd\u672c\u6cf0\u8f14\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5409\u5ca1\u7950\u4eae\uff0c\u843d\u8c37\u5b5d\u5e83\uff0c\u67f3\u8c37\u7f8e\u6c99\uff0c\u68ee\u672c\u771f\u5f18\uff0c\u83ca\u5730\u3000\u592e\uff0c\u912d\u3000\u6f22\u5fe0\uff0c\u5317\u5ddd\u5584\u653f\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u9ad8\u8ee2\u79fb\u6027\u816b\u760dmiR\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u306b\u304a\u3051\u308bIL-6\u3092\u4ecb\u3057\u305f\u85ac\u5264\u8010\u6027\u8a98\u5c0e\uff0c\u7b2c49\u56de\u5317\u6d77\u9053\u75c5\u7406\u8ac7\u8a71\u4f1a\uff0c2016.10.15\uff08\u672d\u5e4c\uff09<\/li>\n<li>\u83ca\u5730\u3000\u592e\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u571f\u5c4b\u90a6\u5f66\uff0c\u4e38\u5c71\u3000\u899a\uff0c\u5b89\u90e8\u5d07\u91cd\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c\u539f\u6797\u3000\u900f\uff0c\u677e\u91ce\u5409\u5b8f\uff0c\u7be0\u539f\u4fe1\u96c4\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u6297\u764c\u5264\u6cbb\u7642\u524d\u5f8c\u306e\u5c3f\u8def\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306eP-glycoprotein \u767a\u73fe\u5909\u5316\uff0c\u7b2c75\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff0c2016.10.7\uff08\u6a2a\u6d5c\uff09<\/li>\n<li>Dorcas A Annan, Maishi N., Soga T., Hida Y., Torii C., Kikuchi H.,<u>\u00a0Hida K.<\/u>\uff1aTumor endothelial cells are resistant to acidic environments\uff0c\u7b2c75\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff0c2016.10.7\uff08\u6a2a\u6d5c\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u3088\u308bbiglycan\u306e\u5206\u6ccc\u3092\u4ecb\u3057\u305f\u304c\u3093\u306e\u8ee2\u79fb\u4fc3\u9032\uff0c\u5e73\u621028\u5e74\u5ea6\u65b0\u5b66\u8853\u9818\u57df\u7814\u7a76\u300c\u5b66\u8853\u7814\u7a76\u652f\u63f4\u57fa\u790e\u5f62\u6210\u3010\u5148\u7aef\u30e2\u30c7\u30eb\u52d5\u7269\u652f\u63f4\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3011\u300d\u82e5\u624b\u652f\u63f4\u6280\u8853\u8b1b\u7fd2\u4f1a\uff0c2016.9.17\uff08\u84fc\u79d1\uff09<\/li>\n<li>\u68ee\u672c\u771f\u5f18\uff0c\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5ddd\u672c\u6cf0\u8f14\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u912d\u6f22\u5fe0\uff0c\u5317\u5ddd\u5584\u653f\uff0c\u9032\u85e4\u6b63\u4fe1\uff0c\u6a0b\u7530\u6cf0\u6d69\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u9ad8\u8ee2\u79fb\u6027\u816b\u760dmiR\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u306b\u304a\u3051\u308bIL-6\u3092\u4ecb\u3057\u305f\u85ac\u5264\u8010\u6027\u8a98\u5c0e\uff0c\u7b2c8\u56de\u65e5\u672cRNA-i\u7814\u7a76\u4f1a\uff0c2016.9.2\uff08\u5e83\u5cf6\uff09<\/li>\n<li>\u83ca\u5730\u3000\u592e\uff0c\u9593\u77f3\u5948\u6e56\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u6297\u764c\u5264\u6cbb\u7642\u524d\u5f8c\u306e\u5c3f\u8def\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306eP-glycoprotein\u767a\u73fe\u5909\u5316\uff0c\u7b2c25\u56de\u65e5\u672c\u304c\u3093\u8ee2\u79fb\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7dcf\u4f1a\uff0c2016.7.21\uff08\u7c73\u5b50\uff09<\/li>\n<li>\u9593\u77f3\u5948\u6e56\uff0c\u79cb\u5c71\u5ee3\u8f14\uff0c\u5927\u8cc0\u5247\u5b5d\uff0c\u6d5c\u7530\u6df3\u4e00\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u3088\u308bbiglycan\u306e\u5206\u6ccc\u3092\u4ecb\u3057\u305f\u304c\u3093\u306e\u8ee2\u79fb\u4fc3\u9032\uff0c\u7b2c25\u56de\u65e5\u672c\u304c\u3093\u8ee2\u79fb\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7dcf\u4f1a\uff0c2016.7.21\uff08\u7c73\u5b50\uff09<\/li>\n<li>\u9ce5\u5c45\u3061\u3055\u307b\uff0c\u9593\u77f3\u5948\u6e56\uff0c<u>\u6a0b\u7530\u4eac\u5b50<\/u>\uff1a\u816b\u760d\u5206\u6ccc\u5c0f\u80demiRNA\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u306e\u85ac\u5264\u8010\u6027\u8a98\uff0c\u7b2c2\u56de\u8840\u7ba1\u751f\u7269\u82e5\u624b\u7814\u7a76\u4f1a\uff0c2016.3.4\uff08\u4ed9\u53f0\uff09<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u7dcf\u8aac\u30fb\u8457\u66f8\uff08\u65e5\u672c\u8a9e\uff09 Hida K., Maishi N., Dorcas Akuba-Muhyia Annan and Hida Y.\uff1aEdit by Takanori Kawaguchi, Cancer Metastasis and Cancer Stem Cell\/Niche, \u201cTumor Endthelial Cells and Cancer Progression\u201d, Bentham &#8230;<a class=\"moretag\" href=\"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/publications\/publications2016\/\">\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":18,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"publications.php","meta":{"footnotes":""},"class_list":["post-163","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"\u7dcf\u8aac\u30fb\u8457\u66f8\uff08\u65e5\u672c\u8a9e\uff09 Hida K., Maishi N., Dorcas Akuba-Muhyia Anna\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" 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