{"id":127,"date":"2019-01-29T15:25:04","date_gmt":"2019-01-29T06:25:04","guid":{"rendered":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol-test\/?page_id=127"},"modified":"2026-01-28T16:17:02","modified_gmt":"2026-01-28T07:17:02","slug":"original","status":"publish","type":"page","link":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/publications\/original\/","title":{"rendered":"\u82f1\u8a9e\u8ad6\u6587"},"content":{"rendered":"

(*corresponding author)\uff08\u00a7\uff1dequally contribution\uff09<\/p>\n

2025<\/h4>\n
    \n
  1. Kakuguchi W, Morimoto M, Takahashi K, Maishi N, Hida K, Nomura T, Otsuguro S, Maenaka K, Ohiro Y\uff1aExploratory transcriptomics and in vivo analyses of suramin in tongue squamous cell carcinoma, Biomed. Rep<\/strong><\/em>.24, 39, 2026, doi. 10.3892\/br.2026.2112<\/li>\n
  2. Niiyama T, Matsuda A, Maishi N, Hida Y, Alam MT, Shinohara S, Mizuno A, <\/span>Ren Z, Lin L, Kakuguchi W, Sakata K, Ohiro Y, Kitagawa Y, Suzuki H, Ueda M, Hida K<\/u>: Localization of high endothelial venules is important for the prognosis of patients with oral squamous cell carcinoma, J. Oral Biosci. <\/em><\/strong>67(4), December 2025, 100695, doi.org\/10.1016\/j.job.2025.100695<\/span><\/li>\n
  3. Ren Z, Matsuda A, Maishi N, Hida Y. Niiyama T, Yu L, Sun W, Ohiro Y,\u00a0 <\/span>Hida K<\/span>*<\/span>\uff1aAnalysis of the distribution of HEV by immunohistochemistry using a mouse oral squamous cell carcinoma model, <\/span>J. Oral Biosci. <\/i><\/b>67(3), September 2025, 100684,<\/span> doi:10.1016\/j.job.2025.100684\u00a0 <\/span><\/li>\n
  4. Sakurai Y, Fujioka Y, Maishi N, Takeda R, Ohba Y, Sasaki M, Teshirogi T, Ito W, Hida Y, Matsuda A, Kido K, Orba Y, Sawa H, and <\/span>Hida K<\/span>*<\/span>\uff1a SARS-CoV-2 uptake and inflammatory response in senescent endothelial cells are regulated by BSG\/VEGFR2 pathway, <\/span>PNAS<\/i><\/b>, <\/span><\/span>doi.org\/10.1073\/pnas.2502724122<\/a><\/span>122 (31) e2502724122,\u00a0 July 28, 2025,<\/li>\n
  5. Ito W,\u00a0 Sakurai Y, Maishi N, Takeda R, Teshirogi T, Yu L, Hida Y, Sasaki M, Orba Y, Tsumita T, \u00a0Watanabe H, Iimura T, Kubo T, Toba S,\u00a0 Sato A, Matsuda A, Kyuno D, Osanai M, Ohiro Y, Torigoe T, Sawa H, H<\/u>ida K<\/u>*\uff1a SARS-CoV-2 infection promotes lung thrombosis by inducing integrin\u03b23 expression in vascular endothelial cells, Sci Rep,<\/em><\/strong> 15(1), 20447, 2025,<\/span>doi: 10.1038\/s41598-025-02784-4<\/span><\/li>\n
  6. Endo R, Ueda T, Nagaoki T, Sato Y, Maishi N, Hida<\/u> K<\/u>, Harashima H, \u204e, Nakamura T: Selective vascular disrupting therapy by lipid nanoparticle-mediated Fas ligand silencing and stimulation of STING, Biomaterials<\/em><\/strong>, 2025 Mar 26:321:123297.\u00a0doi: 10.1016\/j.biomaterials.2025.123297.<\/li>\n
  7. Chida T<\/span>\u00a7<\/span>,\u00a0 Matsuda\u00a0A<\/span>\u00a7<\/span>\u00a0,\u00a0 Maishi\u00a0N,\u00a0 Nakajima K,\u00a0 Sato\u00a0M,\u00a0 Jia Z ,\u00a0 Ohiro<\/span> Y,\u00a0Ogawa\u00a0M,\u00a0 Hida\u00a0Y*,\u00a0 <\/span>Hida\u00a0K<\/span>*: Histopathological analysis of tumor microenvironmental changes after near-infrared photoimmunotherapy, <\/span>Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology (JOMSMP)<\/i><\/b>, Available online 22 Jan 2025, doi.org\/10.1016\/j.ajoms.2025.01.006<\/span><\/li>\n<\/ol>\n

    2024<\/h4>\n
      \n
    1. Jia Z, Maishi N, Takekawa H, Yanagawa Matsuda A, Nakade T, Nakamura T, Harashima H, Hida Y, <\/span>Hida K<\/span>*<\/span>: Targeting Tumor Endothelial Cells by EGCG Using Specific Liposome Delivery System Inhibits Vascular Inflammation and Thrombosis, <\/span>Cancer Medicine<\/i><\/b>. 2024 Dec 04<\/span>. <\/b>13(23): e70462. Doi: org\/10.1002\/cam4.70462<\/span><\/li>\n
    2. Baba S,Kawasaki T,\u00a0Hirano S, \u00a0Nakamura T,\u00a0Asano T,\u00a0Okazaki R, Yoshida K, Kawase T, \u00a0\u00a0Kurahara H, \u00a0Oi H, \u00a0\u00a0Yokoyama M, Kita J,\u00a0\u00a0Imura J, \u00a0Kinoshita K,\u00a0Kondo S, Okada M,\u00a0Satake T,\u00a0 Shimoda\u00a0Igawa Y, Yoshida T,\u00a0Yamaguchi H, Ando Y,\u00a0Mizunuma M,\u00a0Ichikawa Y,\u00a0Hida K\u00a0, Nishihara H,\u00a0Kato Y: A noninvasive urinary microRNA-based assay for the detection of pancreatic cancer from early to late stages: a case control study, e Clinical Medicine<\/em><\/strong>.<\/em> 2024 Nov 11<\/li>\n
    3. Lee JW, Mizuno K, Watanabe H, Lee IH, Tsumita T, Hida K, Yawaka Y, Kitagawa Y, Hasebe A, Iimura T, Kong SW: Enhanced phagocytosis associated with multinucleated microglia via Pyk2 inhibition in an acute \u03b2-amyloid infusion model, J Neuroinflammation. 2024 Aug 6;21(1):196. doi: 10.1186\/s12974-024-03192-7.<\/li>\n
    4. Miho Tokumasu, Mikako Nishida, Weiyang Zhao, Ruoyu Chao, Natsumi Imano ,Nahoko Yamashita, Kyoko Hida, Hisamichi Naitoc and Heiichiro Udono: Metformin synergizes with PD-1 blockade to promote normalization of tumor vessels via CD8T cells and IFN\u03b3, PNAS, e2404778121, doi.org\/10.1073\/pnas.2404778121<\/li>\n<\/ol>\n

      2023<\/h4>\n
        \n
      1. Tsumita T\u00a0\u00a7\uff0cTakeda R\u00a0\u00a7, Maishi N, Hida Y, Sasaki M, Orba Y, Sato A, Toba S, Ito W, Teshirogi T, Sakurai Y, Iba T, Naito H, Ando H, Watanabe H, Mizuno A, Nakanishi T, Matsuda A, Zixiao R, Lee JW\uff0cIimura T,\u00a0 Sawa H*,\u00a0 <\/span>Hida K<\/span>*: Viral uptake and pathophysiology of the lung endothelial cells in age-associated severe SARS-CoV-2 infection models,<\/span> Aging Cell<\/i><\/b>,<\/span><\/span>2023, 23(2), e14050, doi: 10.1111\/acel.14050<\/li>\n

      2. \n\u5317\u6d77\u9053\u5927\u5b66\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u300c        \u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u304c\u82e5\u8005\u3088\u308a\u3082\u9ad8\u9f62\u8005\u3067\u3088\u308a\u91cd\u75c7\u5316\u3057\u3084\u3059\u3044\u306e\u306f\u306a\u305c\u304b\uff1f\uff5e\u80ba\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u52a0\u9f62\u5909\u5316\u304c\u91cd\u75c7\u5316\u75c5\u614b\u306e\u80cc\u666f\u306e\u4e00\u3064\u3060\u3063\u305f\uff01\u301c<\/a><\/span><\/span>\u300d<\/span><\/li>\n
      3. \u00a0Kikuchi H, Maishi N, YU L, Jia Z, Li C, Sato M, Takeda R, Ishizuka K, Hida Y, Shinohara N and *Hida K,: Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer, Br J Cancer, 130, 336\u2013345 (2024), doi:10.1038\/s41416-023-02498-2
        \n\u5317\u6d77\u9053\u5927\u5b66\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u300c        \u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\u306e\u4f4e\u7528\u91cf\u7dad\u6301\u6295\u4e0e\u306f\u6297\u816b\u760d\u52b9\u679c\u3092\u5897\u5f37\u3059\u308b\uff5e\u6297\u304c\u3093\u5264\u306b\u3088\u308b\u708e\u75c7\u6027\u5909\u5316\u3092\u6291\u3048\u3001\u816b\u760d\u8840\u7ba1\u3092\u6b63\u5e38\u5316\u3059\u308b\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u6848\uff5e<\/a><\/span><\/span><\/span>\u300d<\/span><\/span><\/li>\n
      4. Yu Li, Hong Y, Maishi N, Yanagawa Matsuda A, Hida Y, Hasebe A,Kitagawa Y, <\/span>Hida K<\/span>*<\/b>: Oral bacterium <\/span>Streptococcus mutans<\/span><\/i> promotes tumor metastasis via thrombosis formation, <\/span>Cancer Sci<\/i><\/b>,<\/span> 115(2), 648-659,2024, doi: 10.1111\/cas.16010
        \n\u5317\u6d77\u9053\u5927\u5b66\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u300c        \u53e3\u8154\u5185\u7d30\u83cc\u306b\u3088\u308b\u8840\u6813\u75c7\u306f\u304c\u3093\u306e\u8ee2\u79fb\u3092\u4fc3\u9032\u3059\u308b\uff5e\u304c\u3093\u60a3\u8005\u306e\u53e3\u8154\u6e05\u6383\u306e\u91cd\u8981\u6027\u3092\u660e\u3089\u304b\u306b\uff5e<\/a>\u300d<\/span><\/li>\n
      5. Morimoto M, Maishi N, Tsumita T, Alam MT, Kikuchi H, Hida Y, Yoshioka Y, Ochiya T, Annan DA, Takeda R, Kitagawa Y, <\/span>Hida K<\/span>: miR-1246 in tumor extracellular vesicles promotes metastasis via increased tumor cell adhesion and endothelial cell barrier destruction, <\/span>Front.<\/i><\/b> Oncol, <\/i><\/b>13<\/span> , <\/span>doi:10.3389\/fonc.2023.973871\/<\/span><\/li>\n
      6. Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, <\/span>Hida K<\/span>: Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy, <\/span>Cancer Med<\/i><\/b>,\u00a0 doi: 10.1002\/cam4.5696
        \n\u5317\u6d77\u9053\u5927\u5b66\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u300c        \u8840\u7ba1\u65b0\u751f\u963b\u5bb3\u5264\u306e\u5148\u884c\u6295\u4e0e\u306f\u6297\u816b\u760d\u52b9\u679c\u3092\u5897\u5f37\u3059\u308b\uff5e\u816b\u760d\u8840\u7ba1\u6b63\u5e38\u5316\u3092\u6d3b\u304b\u3057\u305f\u65b0\u305f\u306a\u6cbb\u7642\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u3092\u63d0\u6848\uff5e<\/a><\/span><\/span>\u300d<\/span><\/li>\n<\/ol>\n

        2022<\/h4>\n
          \n
        1. Nurina Febriyanti Ayuningtyas, Chanbora Chea, Toshinori Ando, Karina Erda Saninggar, Keiji Tanimoto, Toshihiro Inubushi, Nako Maishi, Kyoko Hida, Masanobu Shindo, Mutsumi Miyauchi *, Takashi Takata *: Bovine lactoferrin suppresses tumor angiogenesis through NF-\u03baB pathway inhibition by binding to TRAF6, <\/span>P<\/i><\/b>harmaceutics<\/i><\/b>, 2022\u00a0<\/span><\/li>\n
        2. Furumido J, Maishi N, Yanagawa-Matsuda A, Kikuchi H, Matsumoto R, Osawa, T, Abe T, ; Matsuno Y, Shinohara N, Hida Y, <\/span>Hida K<\/span>: Stroma Biglycan Expression can be a Prognostic Factor in Prostate Cancers, <\/span>Int J Urol, <\/i><\/b>2022 (IF=3.011)<\/span> ,\u00a0<\/span>in press<\/span><\/li>\n
        3. Takeda R, Sawa H, Sasaki M, Orba Y, Maishi N, Tsumita T, Ushijima6 N, Hida Y, Sano H, Kitagawa Y &<\/span> Hida K<\/span>: Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2, <\/span>Sci Rep<\/i><\/b>, \u00a0(2022) 12:14050<\/span><\/li>\n
        4. Yu L, Maishi N, Akahori E, Hasebe A, Takeda R, Yanagawa-Matsuda A, Hida Y, Nam Jin-Min, Onodera Y, Kitagawa Y, <\/span>Hida K<\/span>: The oral bacterium Streptococcus mutans\u00a0 promotes tumor metastasis by inducing vascular inflammation, <\/span>Cancer Sci<\/i><\/b>, 2022;00:1-15<\/span><\/li>\n
        5. TsumitaT, Maishi N, Annan DA, Alam MT, Matsuda A, Onodera Y, Nam JM, Hida Y, Hida K<\/u>: The oxidized-LDL\/LOX-1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells, Int. J. Cancer<\/i><\/b>, 151(6), 944-956, 2022 (selected as a cover)\u00a0<\/span><\/li>\n
        6. Maishi N, Sakurai Y, Hatakeyama H, Umeyama Y, Nakamura T, Endo R, Alam MT, Li C, Annan DA, Kikuchi H, Morimoto H, Morimoto M, Akiyama K, Ohga N, Hida Y, Harashima H, *Hida K<\/u>: Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell-specific liposomal siRNA delivery system, Cancer Sci.<\/em><\/strong>113(5):1855-1867. May 2022<\/li>\n<\/ol>\n

          2021<\/h4>\n
            \n
          1. Nishiyama K, Takahashi K, Fukuyama M, Kasuya M, Imai A, Usukura T, Maishi N, Maeki M, Ishida A, Tani H, Hida K<\/u>, Shigemura K, Hibara A, Tokeshi M: Facile and rapid detection of SARS-CoV-2 antibody based on a noncompetitive fluorescence polarization immunoassay in human serum samples, Biosens Bioelectron,<\/em><\/strong> (2021) 190:113414.<\/li>\n
          2. Torii C, Maishi N, Kawamoto T, Morimoto M, Akiyama K, Yoshioka Y, Minami T, Tsumita T, Alam MT, Ochiya T, Hida Y, *Hida K<\/u>: miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells, Sci Rep<\/em><\/strong>, (2021) 11:13502<\/li>\n
          3. Li C, Maishi N, Annan DA, Young MF, Morimoto H, Morimoto M, Nam JM, Hida Y,\u00a0*Hida K<\/u>: Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy, Breast Cancer Res<\/em><\/strong>, (2021) 23:51<\/li>\n
          4. Yanagiya M, Dawood RIH, Maishi N, Hida Y, Torii C, Annan DA, Kikuchi H, Yanagawa Matsuda A, Kitamura T, Tei K, Shindoh M, Tanaka S, Kitagawa Y, *Hida K<\/u>: Correlation between endothelial chemokine receptor 7CXCR7 expression and clinicopathological factors in oral squamous cell carcinoma, Pathol Int<\/em><\/strong>, 2021:71:383\u2013391<\/li>\n
          5. Morimoto H, Hida Y, Maishi N, Nishihara H, Hatanaka Y, Li C, Matsuno Y, Nakamura T, Hirano S, *Hida K<\/u>: Biglycan, tumor endothelial cell secreting proteoglycan, as possible biomarker for lung cancer, Thorac Cancer<\/em><\/strong>, 12(9), 1347-1357, 2021<\/li>\n<\/ol>\n

            2020<\/h4>\n
              \n
            1. Hiradate R, Khalil IA, Matsuda A, Sasaki M, Hida K<\/u>, Harashima H: A novel dual-targeted rosiglitazone-loaded nanoparticle for the prevention of diet-induced obesity via the browning of white adipose tissue, J Controlled Release<\/em><\/strong>, 329(10), 665-675, 2020<\/li>\n
            2. Kikuchi H, Maishi N, Dorcas A. Annan, Mohammad Towfik Alam, Randa Ibrahim Hassan Dawood, Sato M, Morimoto M, Takeda R, Ishizuka K, Matsumoto R, Akino T, Tsuchiya K, Abe T, Osawa T, Miyajima N, Maruyama S, Harabayashi T, Azuma M, Yamashiro K, Ameda K, Kashiwagi A, Matsuno Y, Hida Y, Shinohara N and\u00a0<\/u>*Hida K<\/u>: Chemotherapy-induced IL-8 upregulates MDR1\/ABCB1 in tumor blood vessels and results in unfavorable outcome,\u00a0 doi:10.1158\/0008-5472.CAN-19-3791 Cancer Res<\/em><\/strong>, 80(14)<\/li>\n
            3. Habiba U, Hossain E, Yanagawa-Matsuda A, Chowdhury A.F.M.A, Tsuda M, Zaman A.U, Tanaka S, Higashino F. Cisplatin Relocalizes RNA Binding Protein HuR and Enhances the Oncolytic Activity of E4orf6 Deleted Adenovirus. Cancers<\/em><\/strong> 12(4), 809.<\/li>\n
            4. Mikawa Y, Towfik Alam M, Hossain E, Yanagawa-Matsuda A, Kitamura T, Yasuda M, Habiba U, Ahmed I, Kitagawa Y, Shindoh M, Higashino F:<\/u>\u00a0 Conditionally Replicative Adenovirus Controlled by the Stabilization System of AU-rich Elements Containing mRNA. Cancers<\/em><\/strong> 12(5), 1205; 2051205. (2020).<\/li>\n
            5. Hossain E, Habiba U, Yanagawa-Matsuda A, Alam A, Ahmed I,\u00a0Alam MT, Yasuda M, Higashino F: Advantages of Using Paclitaxel in Combination with Oncolytic Adenovirus Utilizing RNA Destabilization Mechanism. Cancers 12(5), 1210 (2020).<\/li>\n
            6. Ahmed I, Towfik Alam M, Yanagawa-Matsuda A, Hossain E, Kitamura T, Minowa K, Higashino F: Enhanced oncolytic activity of E4orf6-deficient adenovirus by facilitating nuclear export of HuR. Biochem Biophys Res Commun<\/em><\/strong>. 529(2):494-499 (2020).<\/li>\n
            7. Yoshimatsu, Yasuhiro, Wakabayashi I, Kimuro S, Takahashi N, Takahashi K, Kobayashi M, Maishi N, Inoue K, Hida K, <\/u>Miyazono K, Watabe T\uff1aTNF-\u03b1 enhances TGF-\u03b2-induced endothelial-to-mesenchymal transition via TGF-\u03b2 signal augmentation, Cancer Sci<\/em><\/strong>,\u00a0111(7), 2385-2399.<\/li>\n<\/ol>\n

              2019<\/h4>\n
                \n
              1. Annan DA, Maishi N, Soga T, Dawood RIH, Li C, Kikuchi H, Hojo T, Morimoto M, Kitamura T, Alam MT, Minowa K, Shinohara N, Nam JM, Hida Y and *Hida K<\/u>\uff1aCarbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment, Cell Commun. Signal.,<\/em><\/strong> 17, 169, 2019<\/li>\n
              2. Maishi N.\u00a7, Kikuchi. H\u00a7, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T, Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y and *Hida K<\/u>: Development of immortalized human tumor endothelial cells from renal cancer, Int. J. Mol. Sci.<\/em><\/strong>, equally contributed, <\/strong>20, 4595, 2019<\/li>\n
              3. Toshihiro Kushibiki, Toru Nakamura, Masumi Tsuda, Takahiro Tsuchikawa, Koji Hontani, Kazuho Inoko, Mizuna Takahashi, Toshimichi Asano, Keisuke Okamura, Soichi Murakami, Yo Kurashima, Yuma Ebihara, Takehiro Noji, Yoshitsugu Nakanishi, Kimitaka Tanaka, Nako Maishi, Katsunori Sasaki, Woong-Ryeon Park, Toshiaki Shichinohe, Kyoko Hida<\/u>, Shinya Tanaka, and Satoshi Hirano\uff1aRole of dimerized C16orf74 in aggressive pancreatic cancer: A novel therapeutic target, Mol Cancer Ther<\/em><\/strong>, 19(1):187-198, 2019<\/li>\n
              4. Ahmed Y AlBaloul, Yusuke Sato, Nako Maishi, Kyoko Hida<\/u>, Hideyoshi Harashima\uff1aTwo modes of toxicity of lipid nanoparticles containing a pH-sensitive cationic lipid on human A375 and A375-SM melanoma cell lines, BPB Reports<\/em><\/strong>, in press<\/li>\n
              5. Sakurai Y., Kato A., Hida Y., Hamada J., Maishi N., Hida K<\/u>., Harashima H.\uff1aSynergistic enhancement of cellular uptake with CD44-expressing malignant pleural mesothelioma by combining cationic liposome and hyaluronic acid-lipid conjugate, J Pharm Sci<\/em><\/strong>, \u00a0108, 3218-3224, 2019<\/li>\n
              6. Yuichi Akatsu, Naoya Takahashi, Yasuhiro Yoshimatsu, Shiori Kimuro, Tomoki Muramatsu, Akihiro Katsura1, Nako Maishi, Hiroshi I. Suzuki, Johji Inazawa, Kyoko Hida<\/u>, Kohei Miyazono, and Tetsuro Watabe\uff1aFibroblast growth factor signals regulate transforming growth factor-\u03b2-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk1, Molecular Oncology,<\/em><\/strong> 13(8), 1706-1724, 2019<\/li>\n<\/ol>\n

                2017<\/h4>\n
                  \n
                1. *Hida K <\/u>\u00a7<\/strong><\/u>, Kawamoto T \u00a7<\/strong>, Maishi N, Morimoto M, Akiyama K, Ohga N, Shindoh M, Shinohara N, Hida Y\uff1amiR-145 Promoted Anoikis Resistance in Tumor Endothelial Cells,\u00a0J Biochem<\/strong><\/em>, 162(2), 81-84<\/li>\n
                2. Hojo T \u00a7<\/strong>, Maishi N.\u00a7<\/strong>, Alam MT, Akiyama K, Ohga N, Shindoh M, Hida Y, Minowa K, Fujisawa T, *Hida K<\/u>\uff1aROS enhance angiogenic properties via regulation of NRF2 in tumor endothelial cells,\u00a0Oncotarget,<\/em><\/strong>\u00a08(28), 45484-45495, 2017<\/li>\n
                3. Torii C, Hida Y, Shindoh M, Akiyama K, Ohga N, Maishi N, Ohiro Y, Ono M, Totsuka Y, Kitagawa Y, Tei K, Sato Y, *Hida K<\/u>\uff1aVasohibin-1 as a novel prognostic factor for head and neck squamous cell carcinoma,\u00a0Anticancer Res<\/em><\/strong>, 37(3), 1219-1225, 2017<\/li>\n
                4. *Hida K<\/u>, Maishi N, Annan DA, Kondoh M, Hojo T, Umma Habiba, Ohga N, Ishikawa K, Sato M, Torii C, Yanagiya M, Morimoto M, Hida Y, Shindoh M\uff1aAneuploidy of murine immortalized endothelial cell line, MS1\uff0cJ Oral Biosci<\/em><\/strong>\uff0c59 (2017), 50-54, 2017<\/li>\n
                5. Habiba U, *Hida K<\/u>, Kitamura T, Yanagawa Matsuda A, Higashino F, Ito M Y, Ohiro Y, Totsuka Y, Shindoh M\uff1a ALDH1 and podoplanin expression patterns predict the risk of malignant transformation in oral leukoplakia, Oncol Lett<\/em><\/strong>, 13(1), 321-328, 2017<\/li>\n<\/ol>\n

                  2016<\/h4>\n
                    \n
                  1. *Hida K<\/u>, Maishi N, Kawamoto T, Akiyama K, Ohga N, Hida Y, Yamada K, Hojo T, Kikuchi H, Sato M, Torii C, Shinohara N, Shindoh M\uff1aTumor endothelial cells express high pentraxin 3 levels, Pathol Int<\/em><\/strong>, 66(12), 687-694, 2016<\/li>\n
                  2. *Hida K<\/u>, Maishi N, Torii C, Yanagiya M, Annan DA, Morimoto M, Alam MT\uff1aComparison of characteristics of mouse immortalized normal endothelial cells, MS1 and primary cultured endothelial cells, Hokkaido Journal of Dental Science<\/em><\/strong>, 37(1), 40-48, 2016<\/li>\n
                  3. Maishi N, Ohba Y, Akiyama K, Ohga N, Hamada J, Nagao-Kitamoto H, Alam MT, Yamamoto K, Kawamoto T, Inoue N, Taketomi A, Shindoh M, Hida Y, *Hida K<\/u>\uff1aTumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan,\u00a0Sci Rep<\/em><\/strong>, 6, 28039\u3014PDF<\/a>\u3015<\/li>\n
                  4. Shahrabi-Farahani S, Gallottini M, Martins F, Li E, Mudge DR, Nakayama H, Hida K<\/u>, Panigrahy D, D\u2019Amore PA, Bielenberg DR\uff1a Neuropilin 1 Receptor is Upregulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma, Am J Pathol,<\/em><\/strong>\u00a0186(4), 1055-1064, 2016<\/li>\n<\/ol>\n

                    2015<\/h4>\n
                      \n
                    1. Yamada K\u00a7<\/strong>, Maishi N \u00a7<\/strong>, Akiyama K, Alam MT, Ohga N, Kawamoto T, Shindoh M, Takahashi N, Kamiyama T, Hida Y, Taketomi A and *Hida K<\/u>\uff1aCXCL 12-CXCR7 axis is important for tumor endothelial cell angiogenic property,\u00a0Int J Cancer<\/em><\/strong>\u00a0137(12), 2825-2836 2015 (selected as a cover)<\/li>\n
                    2. Matsumoto R, Tsuda M, Wang L; Maishi N, Abe T, Kimura T, Tanino M, Nishihara H, Hida K<\/u>, Ohba Y, Shinohara N, Nonomura K, Tanaka S,\uff1aAdaptor protein CRK induces epithelial\u2013mesenchymal transition and metastasis of bladder cancer cells through HGF\/c-Met feedback loop, Cancer Sci<\/em><\/strong>, 106(6), 709-717<\/li>\n
                    3. Akiyama K, Ohga N, Hida Y, Maishi N, Ohba Y, Alam MT, Kawamoto T, Ohmura H, Yamada K, Torii C, Shindoh M and *Hida K<\/u>\uff1aInhibition of multidrug transporter in tumor endothelial cells enhances antiangiogenic activity\uff0cAm J Pathol<\/em><\/strong>,185(2), 572-580, 2015<\/li>\n<\/ol>\n

                      2014<\/h4>\n
                        \n
                      1. Kibria G, Hatakeyama H,Akiyama K,\u00a0<\/u><\/em>Hida K <\/u>and Harashima H\uff1aComparative Study of the Sensitivities of Cancer Cells to Doxorubicin, and Relationships between the Effect of the Drug-Efflux Pump P-gp\uff0cBiol. Pharm. Bull.<\/em><\/strong>37(12), 1926\u20131935, 2014<\/li>\n
                      2. Ohmura-Kakutani H.\u00a7<\/strong>, Akiyama K, \u00a7<\/strong>Maishi N, Ohga N, Hida Y, Kawamoto T, Iida J, Shindoh M, Tsuchiya K, Shinohara N, *Hida K<\/u>\uff1aIdentification of Tumor Endothelial Cells with High Aldehyde Dehydrogenase Activity and a Highly Angiogenic Phenotype, PLoS ONE<\/em><\/strong>, \u00a09(12):e113910, 2014<\/li>\n
                      3. Akhter A, Hayashi Y, Sakurai Y, Ohga N, Hida K<\/u>, Harashima H\uff1aLigand density at the surface of a nanoparticle and different uptake mechanism: Two important factors for successful siRNA delivery to liver endothelial cells, Int J Pharm<\/em><\/strong>\uff0c475 (1-2):227-237, 2014<\/li>\n
                      4. Ara MN, Matsuda T, Hyodo M, Sakurai Y, Ohga N, Hida K<\/u>\uff1aConstruction of an aptamer modified liposomal system targeted to tumor endothelial cells,\u00a0Bio Pharm Bull,\u00a0<\/em><\/strong>37(11):1742-9, 2014<\/li>\n
                      5. Alam MT.\u00a7, <\/strong>Nagao-Kitamoto H.\u00a7<\/strong>, Ohga N, Akiyama K, Maishi N, \u00a0Kawamoto T, Shinohara N, Taketomi A, Shindoh M, Hida Y and *Hida K<\/u>\uff1aSuprabasin as a novel tumor endothelial cell marker,\u00a0Cancer Sci<\/em><\/strong>, 105(12), 1533\u20131540, 2014<\/li>\n
                      6. Ara MN, Matsuda T, Hyodo M, Sakurai Y, Hatakeyama H, Ohga N, Hida K<\/u>, Harashima H\uff1aAn aptamer ligand based liposomal nanocarrier system that targets tumor endothelial cells\uff0cBiomaterials<\/em><\/strong>, 35(25), 7110-7120, 2014<\/li>\n
                      7. Ara MN, Hyodo M, Ohga N, Akiyama K, Hida K<\/u>, Hida Y, Shinohara N, Harashima H\uff1aIdentification and expression of troponin T, a new marker on the surface of cultured tumor endothelial cells by aptamer ligand, Cancer Med<\/em><\/strong>, 3(4), 825-834, 2014<\/li>\n
                      8. Otsubo T, Hida Y, Ohga N, Sato H, Kai T, Matsuki Y, Takasu H, Akiyama K, Maishi N, Kawamoto T, Shinohara N, Nonomura K, *Hida K<\/u>\uff1aIdentification of Novel Targets for Antiangiogenic Therapy by Comparing the Gene Expressions of Tumor and Normal Endothelial Cells,\u00a0Cancer Sci<\/i><\/b>, 105(5), 560-567, 2014<\/li>\n
                      9. Habiba U, Kitamura T, Yanagawa-Matsuda A, Hida K<\/u>, Higashino F, Ohiro Y, Totsuka Y and Shindoh M\uff1aCytoplasmic expression of HuR may be a valuable diagnostic tool for determining the potential for malignant transformation of oral verrucous borderline lesions,\u00a0Oncol Rep<\/i><\/b>, 31(4), 1547-1554, 2014<\/li>\n
                      10. Sakurai Y, Hatakeyama H, Sato Y, Hyodo M, Akita H,Ohga N, Hida K<\/u>, Harashima H\uff1aRNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system, J Control Release<\/em><\/strong>, 173(10), 110-118, 2014<\/li>\n<\/ol>\n

                        2013<\/h4>\n
                          \n
                        1. Kondoh M \u00a7<\/strong>, Ohga N \u00a7<\/strong>, Akiyama K \u00a7<\/strong>, Hida Y, Maishi N, Towfik AM, Inoue N, Shindoh M and *Hida K<\/u>\uff1aHypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment,\u00a0PLoS ONE<\/em><\/strong>, 8(11), e80349, 2013<\/li>\n
                        2. Akhter A, Hayashi Y, Sakurai Y, Ohga N, Hida K<\/u>, Harashima H\uff1aA liposomal delivery system that targets liver endothelial cells based on a new peptide motif present in the ApoB-100 sequence\uff0cInt J Pharm<\/em><\/strong>\uff0c456(1)\uff0c195-201, 2013<\/li>\n
                        3. Osawa T, Ohga N, Akiyama K, Hida Y, Kitayama K, Kawamoto T, Yamamoto K, Maishi N, Kondoh M, Onodera Y, Fujie M, Nonomura K, Shindoh M and *Hida K<\/u>\u00a0: Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis,\u00a0Br J Cancer<\/em><\/strong>, 109(8), 2237-2247, 2013<\/li>\n
                        4. Maishi N, Kawamoto T, Ohga N,Yamad K, Akiyama K, Yamamoto K , Osawa T, Hida Y and\u00a0<\/span>*Hida K<\/u>.<\/u>:\u00a0<\/strong>Application of POLARIC\u2122 fluorophores in an\u00a0in vivo\u00a0<\/em>tumor model,\u00a0Oncol Rep<\/em><\/strong>, 30(4), 1695-1700, 2013<\/li>\n
                        5. Kibria G, Hatakeyama H, Ohga N. Hida K<\/u>, Harashima H\uff1aThe effect of liposomal size on the targeted delivery of doxorubicin to Integrin alpha v beta 3-expressing tumor endothelial cells, Biomaterials<\/em><\/strong>, 34(22), 5617-5627, 2013<\/li>\n
                        6. Nagamine K, Kitamura T, Yanagawa -Matsuda A, Ohiro Y, Tei K, Hida K<\/u>, Higashino F, Totsuka Y and Shindoh M\uff1a Expression of parathyroid hormone-related protein confers malignant potential to mucoepidermoid carcinoma, Oncol Rep<\/em><\/strong>, 29(6), 2114-2118, 2013<\/li>\n
                        7. Yamada Y, Hashida M, Hayashi Y, Tabata M, Hyodo M, Ara MN, Ohga N, Hida K<\/u>, Harashima H\uff1aAn approach to transgene expression in liver endothelial cells using a liposome-based gene vector coated with hyaluronic acid, J Pharm Sci,<\/em><\/strong>102(9), 3119-3127, 2013<\/li>\n
                        8. Akiyama K, Ohga N, Maishi N, Hida Y, Kitayama K, Kawamoto T, Osawa T, Suzuki Y, Shinohara N, Nonomura K, Shindoh M, *Hida K<\/u>\u00a0: The F-prostaglandin receptor is a novel marker for tumor endothelial cells in renal cell carcinoma,\u00a0Pathol Int,<\/em><\/strong>63(1), 37-44, 2013\u00a0\u3014PDF\u3015<\/a><\/li>\n<\/ol>\n

                          2012<\/h4>\n
                            \n
                          1. Ara MN, Hyodo M, Ohga N, Hida K<\/u>, Harashima H: Development of a novel DNA aptamer ligand against primary cultured tumor endothelial cells, PLoS ONE<\/em><\/strong>, 7(12), e50174, 2012<\/li>\n
                          2. Takara K, Hatakeyama H, Kibria G, Ohga N, Hida K<\/u>, Harashima H\uff1aSize-controlled, dual-ligand modified liposomes that target the tumor vasculature show promise foruse in drug-resistant cancer therapy, J Controlled Release<\/em><\/strong>, 162(1), 225-232, 2012<\/li>\n
                          3. Osawa T, Ohga N, Hida Y, Kitayama K, Akiyama K, Onodera Y, Fujie M, Shinohara N, Nonomura K, Shindoh M, *Hida K<\/u>: Prostacyclin receptor in tumor endothelial cells promotes angiogenesis in an autocrine manner,\u00a0Cancer Sci<\/strong><\/em>, 103(6), 1038-1044, 2012<\/li>\n
                          4. Kawamoto T, Ohga N, Akiyama K, Hirata N, Kitahara S, Maishi N, Osawa T, Yamamoto K, Kondoh M, Shindoh M, Hida Y, *Hida K<\/u>: Tumor-derived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis,\u00a0PLoS ONE\u00a0<\/em><\/strong>7(3) :e34045, 2012<\/li>\n
                          5. Yamamoto K, Ohga N, Hida Y, Maishi N, Kawamoto T, Kitayama K, Akiyama K, Osawa T. Kondoh M, Matsuda K, Onodera Y, Fujie M, Kaga K, Hirano S, Shinohara N., Shindoh M., *Hida K.<\/u>: Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells,\u00a0Br J Cancer<\/em><\/strong>, 106(6), 1214-1223, 2012<\/li>\n
                          6. Maishi N, Ohga N, Hida Y, Akiyama K, Kitayama K, Osawa T, Onodera Y, Nonomura K, Shinohara N, Shindoh M, *Hida K<\/u>\u00a0: CXCR7 : A novel tumor endothelial marker in renal cell carcinoma,\u00a0Pathol Int,\u00a0<\/em><\/strong>62(5), 309-317, 2012<\/li>\n
                          7. Ohga N, Ishikawa S, Maishi N, Akiyama K, Hida Y, Kawamoto T, Sadamoto Y, Osawa T, Yamamoto K, Kondoh M, Ohmura H, Shinohara N, Nonomura K, Shindoh M, *Hida K<\/u>\uff1aHeterogeneity of Tumor Endothelial Cells: Comparison between Tumor Endothelial Cells Isolated from Highly Metastatic and Low Metastatic Tumors,\u00a0Am J Pathol<\/em><\/strong>, 180(3), 1294-1307, 2012<\/li>\n
                          8. Akiyama K, Ohga N, Hida Y, Kawamoto T, Sadamoto Y, Ishikawa S, Maishi N, Akino T, Kondoh M, Matsuda A, Inoue N, Shindoh M and *Hida K<\/u>.: Tumor endothelial cells acquire drug resistance by MDR1 upregulation via VEGF signaling in tumor microenvironment,\u00a0Am J Pathol<\/em><\/strong>, 180(3), 1283-1293, 2012<\/li>\n<\/ol>\n

                            2011<\/h4>\n
                              \n
                            1. Kibria G, Hatakeyama H, Ohga N, Hida K<\/u>, Harashima H: Dual-ligand modification of PEGylated liposomes shows better cell selectivity and efficient gene delivery, J Controlled Release<\/em><\/strong>, 153(2), 141-148, 2011<\/li>\n
                            2. Muraki C \u00a7<\/strong>, Ohga N\u00a7<\/strong>, Hida Y, Nishihara H, Kato Y, Tsuchiya K, Matsuda K, Totsuka Y, Shindoh M and *<\/u>Hida K.\u00a7<\/strong><\/u>: Cyclooxygenase-\u00a0Int J Cancer,<\/em><\/strong>130(1), 59-72, 2011<\/li>\n
                            3. Kurosu T, Ohga N, Hida Y, Maishi N, Akiyama K, Kakuguchi W, Kuroshima T, Kondo M, Akino T, Totsuka Y, Shindoh M, Higashino F and *Hida K.<\/u>: HuR keeps an angiogenic switch on by stabilizing mRNA of VEGF and COX-2 in tumor endothelium,Br J<\/em><\/strong>\u00a0Cancer<\/em><\/strong>, 104(5), 819-829, 2011\u00a0\u3014PDF\u3015<\/a><\/li>\n
                            4. Nitta Y, Hida K<\/u>, Kitamura T, Higashino F, Ohga N, Fukushima K, Shindoh M: Phenotype of tumor lymphatic vessels is a prognostic factor in human tongue squamous cell carcinoma, Oncol Lett<\/em><\/strong>, 2(1), 79-83, 2011<\/li>\n<\/ol>\n

                              2010<\/h4>\n
                                \n
                              1. Takara K, Hatakeyama H, Ohga N, Hida K*<\/u>, Harashima H: Design of a dual-ligand system using a specific ligand and cell penetrating peptide, resulting in a synergistic effect on selectivity and cellular uptake,Int J Pharm<\/em><\/strong>, 396(1-2), 143-148, 2010<\/li>\n
                              2. Kajimoto K, Hossen MN, Hida K,<\/u> Ohga N, Akita H, Hyodo M, Hida Y and Harashima H: Isolation and Culture of Microvascular Endothelial Cells from Murine Inguinal and Epididymal Adipose Tissue, J Immunol Methods<\/em><\/strong>, 357(1-2),43-50, 2010<\/li>\n
                              3. Matsuda K \u00a7<\/strong>, Ohga N \u00a7<\/strong>, Hida Y, Muraki C, Kurosu T, Tsuchiya K, Akino T, Shih SC, Totsuka Y, Klagsbrun M, Shindoh M and *Hida K<\/u>\uff1aIsolated tumor endothelial cells maintain specific character during long-term culture,\u00a0Biochem Biophys Res Commun<\/em><\/strong>, 394(4), 947- 954, 2010<\/li>\n
                              4. Suzuki Y, Ohga N, Morishita Y, Hida K<\/u>, Miyazono K, and Watabe T: BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo, J Cell Sci<\/em><\/strong>, 123(10), 1684-1692, 2010<\/li>\n
                              5. Tsuchiya K, *Hida K<\/u>, Hida Y, Muraki C, Ohga N, Kondo T, Miseki T, Nakagawa K, Shindoh M, Harabayashi T, Shinohara N, Nonomura K and Kobayashi M: Adrenomedullin antagonist suppresses tumor formation in renal cell carcinoma through inhibitory effects on tumor endothelial cells and endothelial progernitor mobilization, Int J Oncol<\/em><\/strong>, 36(6), 1379-1386, 2010<\/li>\n<\/ol>\n

                                2009<\/h4>\n
                                  \n
                                1. Ohga N,*Hida K<\/u>, Hida Y, Muraki C, Tsuchiya K, Matsuda K, Ohiro Y, Totsuka Y and Shindoh M: Inhibitory Effects ofEpigallocatechin-3 Gallate, a Polyphenol in Green Tea, on Tumor-Associated Endothelial Cells and Endothelial Progenitor Cells. Cancer Sci<\/em>,<\/strong>\u00a0100(10), 1963-1970, 2009<\/li>\n
                                2. Akino T.,\u00a0*Hida K.<\/u>, Hida Y., Tsuchiya K., Freedman D., Muraki C., Ohga N., Matsuda K., Akiyama K., Harabayashi T., Shinohara N., Nonomura K., Klagsbrun M. and Shindoh M.: Cytogenetic\u3000Abnormalities of Tumor-Associated Endothelial Cells in Human Malignant Tumor.\u00a0Am J Pathol<\/em>,<\/strong>175(6), 2657-2667, 2009\u00a0\u3014PDF\u3015<\/a><\/li>\n
                                3. Tanaka S, Kitamura T, Higashino F,\u00a0Hida K.<\/strong><\/u>, Ohiro Y, Ono M, Kobayashi M, Totsuka Y, Shindoh M: Pim-1 activates cell motility that induces malignant phenotype of tongue squamous cell carcinoma.\u00a0Mol Med Rep<\/em><\/strong>, 2(2):313-318, 2009.<\/li>\n<\/ol>\n

                                  2008\u5e74\u4ee5\u524d<\/h4>\n
                                    \n
                                  1. Dudley AC, Shih SC, Cliffe AR, Hida K\u00a0<\/u>and Klagsbrun M: Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine.\u00a0Br J Cancer<\/em><\/strong>, 99(1), 118-125, 2008.<\/li>\n
                                  2. Hata H, Kitamura T, Higashino F, Hida K<\/u>, Yoshida K, Ohiro Y, Totsuka Y, Kitagawa Y and Shindoh M: Expression of E1AF, and ets-oncogene transcription factor, expression highly correlates with malignant phenotype of malignant melanoma through upregulating membrane-type-1 matrix metalloproteinase gene. Oncol Rep,<\/em><\/strong>\u00a019(5), 1093-1098, 2008<\/li>\n
                                  3. Amin DN, Hida K,<\/strong><\/u> Bielenberg DR and Klagsbrun M:Expression of epidermal growth factor (EGF) receptor but not ErbB3 in Tumor endothelial cells coincides with responsiveness to EGF and sensitivity to EGFR kinase inhibitors. Cancer Res.,<\/em><\/strong>\u00a066 (4), 2173-2180, 2006<\/li>\n
                                  4. Hida K<\/u>, Hida Y, Amin D, Flint A, Panigrahy D, Morton C and Klagsbrun M:Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res.,<\/em><\/strong>\u00a064(22), 8249-8255, 2004\u00a0\u3014PDF\u3015<\/a><\/li>\n
                                  5. Shindoh M, Adachi M, Higashino F, Yasuda M, Hida K.,<\/strong><\/u> Nishioka K, Takayama S, Reed JC, Imai K, Totsuka Y and Kohgo T: BAG-1 expression correlates highly with the malignant potential in early lesions (T1 and T2) of oral squamous cell carcinoma. Oral Oncol<\/em><\/strong>, 36(5), 444-449, 2000<\/li>\n
                                  6. Hanzawa M, Shindoh M, Higashino F, Yasuda M, Hida K,<\/strong><\/u> Kohgo T, Nakamura M, Notani K, Totsuka Y, Yoshida K and Fujinaga K: Hepatocyte growth factor upregulates E1AF that induces oral squamous cell carcinoma (SCC) cell invasion by activating matrix metalloproteinase genes. Carcinogenesis<\/em><\/strong>, 21(6), 1079-1085, 2000<\/li>\n
                                  7. Hida K,<\/strong><\/u> Shindoh M, Yoshida K, Yasuda M, Hanzawa M, Funaoka K, Kohgo T, Amemiya A,\u00a0 Totsuka Y and Fujinaga K: Antisense E1AF transfection restrains oral cancer invasion by reducing MMPs activities. Am J Pathol<\/em><\/strong>, 150, 2125-2132, 1997<\/li>\n
                                  8. Hida K<\/u>, Shindoh M, Yoshida K, Kudoh A, Funaoka K, Kohgo T, Fujinaga K and Totsuka Y: Expression of E1AF, an ets-family transcription factor, is correlated with the invasive phenotype of oral squamous cell carcinomas. Oral Oncol,<\/em><\/strong>\u00a033(6), 426-430, 1997<\/li>\n
                                  9. Funaoka K, Shindoh M, Yoshida K,Hanzawa M, Hida K<\/u>, Nishikata S, Totsuka Y and Fijinaga K: Activation of the p21(Waf1\/Cip1) promoter by the ets oncogene family transcription factor E1AF, Biochem Biophys Res Commun<\/em><\/strong>, 236(1), 79-82, 1997<\/li>\n
                                  10. Shindoh M, Higashino F, Kaya M, Yasuda M, Funaoka K, Hanzawa M, Hida K<\/u>, Kohgo T, Amemiya A, Yoshida K and Fujinaga K: Correlated expression of matrix metalloproteinases and ets-family transcription factor E1A-F in invasive oral-squamous-cell-carcinoma-derived cell lines. Am J Pathol<\/em><\/strong>, 148(3), 693-700, 1996.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

                                    (*corresponding author)\uff08\u00a7\uff1dequally contribution\uff09 2025 Kakuguchi W, Morimoto M, Takahashi K, Maishi N, Hida K, Nomura T, Otsuguro S, Maenaka K, Ohiro Y\uff1aExploratory transcriptomics and in vivo analyses o…\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":18,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"publications.php","meta":{"footnotes":""},"class_list":["post-127","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/pages\/127","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/comments?post=127"}],"version-history":[{"count":86,"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/pages\/127\/revisions"}],"predecessor-version":[{"id":1508,"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/pages\/127\/revisions\/1508"}],"up":[{"embeddable":true,"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/pages\/18"}],"wp:attachment":[{"href":"https:\/\/www.den.hokudai.ac.jp\/vascular-biol-pathol\/wp-json\/wp\/v2\/media?parent=127"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}