{"id":252,"date":"2025-04-21T22:09:51","date_gmt":"2025-04-21T13:09:51","guid":{"rendered":"https:\/\/www.den.hokudai.ac.jp\/kouge1\/wordpress\/?p=252"},"modified":"2025-04-21T22:09:52","modified_gmt":"2025-04-21T13:09:52","slug":"%e5%ad%a6%e4%bc%9a%e7%99%ba%e8%a1%a8%ef%bc%882018%e5%b9%b4%e4%bb%a5%e5%89%8d%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.den.hokudai.ac.jp\/kouge1\/research\/252","title":{"rendered":"\u5b66\u4f1a\u767a\u8868\uff082018\u5e74\u4ee5\u524d\uff09"},"content":{"rendered":"\n

<\/i>\u5b66\u4f1a\u767a\u8868<\/span><\/span><\/h3>\n\n\n\n

\u5e73\u621020\u5e74\uff082008\u5e74\uff09<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u6839\u6cbb\u5207\u9664\u3092\u884c\u3063\u305f\u53e3\u5e95\u6241\u5e73\u4e0a\u76ae\u764c56\u4f8b\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\uff08\u5225\u5e9c\uff092008\u5e741\u6708 \u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u8a8c20\u5dfb3\u53f7 Page189(2008.09)<\/p>\n\n\n\n

\u4e98\u7406 \u6587\u592b, \u6a2a\u5c71 \u6566\u90ce, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f, \u68ee\u7530 \u5b66, \u516b\u82e5 \u4fdd\u5b5d, \u5ddd\u6d6a \u96c5\u5149\uff1a\u6750\u6599\u306e\u30ca\u30ce\u30b5\u30a4\u30b8\u30f3\u30b0\u306b\u57fa\u3065\u304f\u751f\u4f53\u53cd\u5fdc\u3068\u305d\u306e\u5fdc\u7528. \u6b6f\u79d1\u533b\u5b66\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u7dcf\u5408\u7684\u306a\u7814\u7a76\u3092\u63a8\u9032\u3059\u308b\u96c6\u3044\uff08\u6771\u4eac\uff092008\u5e741\u6708 \u65e5\u672c\u6b6f\u79d1\u533b\u5b66\u4f1a\u8a8c27\u5dfb Page90(2008.03)<\/p>\n\n\n\n

\u4e45\u4fdd\u6728 \u82b3\u5fb3, \u5bfa\u7530 \u5178\u5b50, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u306e\u30c8\u30ea\u30d7\u30eb\u30d8\u30ea\u30af\u30b9\u69cb\u9020\u304c\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3068\u306e\u53cd\u5fdc\u306b\u5fc5\u9808\u3067\u3042\u308b. \u7b2c20\u56de\u4ee3\u7528\u81d3\u5668\u518d\u751f\u533b\u5b66\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092008\u5e742\u6708 \u5317\u6d77\u9053\u5916\u79d1\u96d1\u8a8c53\u5dfb1\u53f7 Page124(2008.06)<\/p>\n\n\n\n

\u4e45\u4fdd\u6728 \u82b3\u5fb3, \u5bfa\u7530 \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u5b87\u5c3e \u57fa\u5f18, \u4e98\u7406 \u6587\u592b\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u3068\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3068\u306e\u53cd\u5fdc\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u7dda\u7dad\u5f62\u6210\u306b\u53ca\u307c\u3059CNT\u306e\u5f71\u97ff. \u539a\u751f\u52b4\u50cd\u79d1\u5b66\u7814\u7a76\u8cbb\u88dc\u52a9\u91d1 \u5316\u5b66\u7269\u8cea\u30ea\u30b9\u30af\u7814\u7a76\u4e8b\u696d \u30ca\u30ce\u5fae\u7c92\u5b50\u306e\u4f53\u5185\u52d5\u614b\u53ef\u8996\u6cd5\u306e\u958b\u767a \u5e73\u621019\u5e74\u5ea6\u51ac\u5b63 \u7b2c3\u56de\u76ee\u6a19\u7b56\u5b9a\u7814\u7a76\u767a\u8868\u4f1a\uff08\u672d\u5e4c\uff092008\u5e742\u6708<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u4e0a\u306b\u591a\u5c64\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3092\u30b3\u30fc\u30c8\u3057\u305f\u7d30\u80de\u57f9\u990a\u62c5\u4f53\u306e\u958b\u767a. \u539a\u751f\u52b4\u50cd\u79d1\u5b66\u7814\u7a76\u8cbb\u88dc\u52a9\u91d1 \u5316\u5b66\u7269\u8cea\u30ea\u30b9\u30af\u7814\u7a76\u4e8b\u696d \u30ca\u30ce\u5fae\u7c92\u5b50\u306e\u4f53\u5185\u52d5\u614b\u53ef\u8996\u6cd5\u306e\u958b\u767a \u5e73\u621019\u5e74\u5ea6\u51ac\u5b63 \u7b2c3\u56de\u76ee\u6a19\u7b56\u5b9a\u7814\u7a76\u767a\u8868\u4f1a\uff08\u672d\u5e4c\uff092008\u5e742\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5f8c\u85e4 \u96bc, \u539f\u6a4b \u7dbe\u5b50, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u553e\u6db2\u4e2d\u306eIL-6\u767a\u73fe\u306b\u3064\u3044\u3066\u306e\u691c\u8a0e(\u7b2c2\u5831)\u3000\u81e8\u5e8a\u30d1\u30e9\u30e1\u30fc\u30bf\u30fc\u304a\u3088\u3073\u77ed\u671f\u4e88\u5f8c\u3068\u306e\u95a2\u9023. \u7b2c62\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092008\u5e744\u6708 \u6284\u9332P206<\/p>\n\n\n\n

\u5927\u5ee3 \u6d0b\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u5c0f\u6cc9 \u96c4, \u5c0f\u91ce \u8ca2\u4f38, \u8db3\u5229 \u96c4\u4e00, \u912d \u6f22\u5fe0, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247\uff1a\u4e0b\u984e\u6b6f\u8089\u764c\u306b\u304a\u3051\u308b\u8853\u524d\u5316\u5b66\u7642\u6cd5\u4f75\u7528\u653e\u5c04\u7dda\u7642\u6cd5\u5f8c\u306e\u816b\u760d\u6b8b\u5b58\u69d8\u5f0f. \u7b2c62\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092008\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfb4\u53f7 Page436(2008.09)<\/p>\n\n\n\n

\u4e2d\u6751 \u88d5\u4ecb, \u5c71\u5d0e \u88d5, \u5f8c\u85e4 \u96bc, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1aCandida glabrata\u306b\u3088\u308b\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c62\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092008\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfb4\u53f7 Page452-453(2008.09)<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aTomoTherapy\u3092\u7528\u3044\u305f\u4e0a\u984e\u764c\u6cbb\u7642\u7d4c\u9a13. \u7b2c62\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092008\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfb4\u53f7 Page489-490(2008.09)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u5317\u68ee \u6b63\u543e, \u79e6 \u6d69\u4fe1, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u75db\u75c7\u306b\u5bfe\u3059\u308b\u30e9\u30d5\u30c1\u30b8\u30f3\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u306e\u691c\u8a0e. \u7b2c62\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092008\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfb4\u53f7 Page530(2008.09)<\/p>\n\n\n\n

Asaka T\uff0c Akiyama M\uff0c Domonn T\uff0c Nishie W\uff0c Fujita Y\uff0c Tanimura S\uff0c Kitagawa Y\uff0c Shimizu H : COL17 is a key player of epithelial-mesenchymal interaction in tooth formation. International Investigative Dermatology 2008(Kyoto), 2008.5.<\/p>\n\n\n\n

Sato J, Goto J, Harahasgi A, Yamazaki Y, Satoh A, Kitagawa Y : Changes in interleukin-6 levels in saliva in patients with oral squamous cell carcinoma during the treatment phase. 12th International Congress on Oral Cancer. (Shanghai), 2008.05 Abstract P150-151<\/p>\n\n\n\n

\u72ac\u4f0f \u6b63\u5e78, \u91d1 \u6c38\u7537, \u79e6 \u6d69\u4fe1, \u6751\u4e95 \u77e5\u4f73, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f\uff1a\u4f4e\u9178\u7d20\u907a\u4f1d\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306e\u305f\u3081\u306e\u30ec\u30dd\u30fc\u30bf\u30fc\u30d9\u30af\u30bf\u30fc\u306e\u958b\u767a. \u5e73\u621020\u5e74\u5ea6\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u5bae\uff092008\u5e745\u6708<\/p>\n\n\n\n

\u4e45\u4fdd\u6728 \u82b3\u5fb3, \u5bfa\u7530 \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u5b87\u5c3e \u57fa\u5f18, \u4e98\u7406 \u6587\u592b\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u3068\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u306e\u76f8\u4e92\u53cd\u5fdc\u306b\u306f\u30c8\u30ea\u30d7\u30eb\u30d8\u30ea\u30af\u30b9\u69cb\u9020\u304c\u5fc5\u9808\u3067\u3042\u308b. \u7b2c40\u56de\u65e5\u672c\u7d50\u5408\u7d44\u7e54\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a \u7b2c55\u56de\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u7814\u7a76\u4f1a\u5927\u4f1a \u5408\u540c\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092008\u5e745\u6708<\/p>\n\n\n\n

Terada M, Takayama M, Kaku T, Ishikawa M, Kitagawa Y, Uo M, Watri F, Kuboki Y : New geometrical matrix for bone regeneration: a honeycomb-shaped \u03b2-TCP ceramics induced straight longitudinal bone inside the tunnels. International Symposium on Nanotoxicology Assessment and Biomedical,\u3000Environmental Application of Fine Particles and Nanotubes (ISNT2008) (Sapporo), 2008.6<\/p>\n\n\n\n

Terada M, Uo M, Kitagawa Y, Watri F : Development of multi walled carbon nanotubes coated collagen for cell culturing. International Symposium on Nanotoxicology Assessment and Biomedical,\u3000Environmental Application of Fine Particles and Nanotubes (ISNT2008) (Sapporo), 2008.6<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f, \u95a2\u5802 \u5145\uff1a\u8457\u3057\u3044\u9aa8\u786c\u5316\u50cf\u3092\u8a8d\u3081\u305f\u4e0b\u984e\u817a\u69d8\u56a2\u80de\u764c\u306e1\u4f8b. \u7b2c32\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c29\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u6771\u4eac\uff092008\u5e746\u6708 \u982d\u9838\u90e8\u764c34\u5dfb2\u53f7 Page221(2008.05)<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u5c0f\u91ce \u8ca2\u4f38, \u91ce\u8c37 \u5065\u4e00, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1a\u982c\u7c98\u819c\u6241\u5e73\u4e0a\u76ae\u764c82\u4f8b\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c32\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c29\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u6771\u4eac\uff092008\u5e746\u6708 \u982d\u9838\u90e8\u764c34\u5dfb2\u53f7 Page228(2008.05)<\/p>\n\n\n\n

\u6751\u4e95 \u77e5\u4f73, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u672c\u9593 \u660e\u5b8f, \u5317\u5ddd \u5584\u653f\uff1a\u5927\u5b66\u75c5\u9662\u306b\u304a\u3051\u308b\u982d\u9838\u90e8\u304c\u3093\u6cbb\u7642\u3078\u306e\u6b6f\u79d1\u7684\u53e3\u8154\u30b1\u30a2\u4ecb\u5165. \u7b2c32\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c29\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u6771\u4eac\uff092008\u5e746\u6708 \u982d\u9838\u90e8\u764c34\u5dfb2\u53f7 Page231(2008.05)<\/p>\n\n\n\n

\u5c0f\u91ce \u8ca2\u4f38, \u4f50\u85e4 \u660e, \u8db3\u5229 \u96c4\u4e00, \u5927\u5ee3 \u6d0b\u4e00, \u912d \u6f22\u5fe0, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247\uff1a\u53e3\u5e95\u764c\u624b\u8853\u4f8b\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c32\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c29\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u6771\u4eac\uff092008\u5e746\u6708 \u982d\u9838\u90e8\u764c34\u5dfb2\u53f7 Page228(2008.05)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6817\u539f \u7d79\u679d, \u8d64\u6839 \u5149\u5ba3, \u9038\u898b \u4ec1, \u767e\u5408\u8349 \u5065\u572d\u5fd7, \u4e0a\u91ce \u5c1a\u96c4, \u4e0a\u689d \u670b\u4e4b, \u98ef\u7530 \u5584\u5e78, \u8349\u6df1 \u516c\u79c0, \u9b3c\u585a \u54f2\u90ce, \u5927\u7530 \u6d0b\u4e8c\u90ce, \u4e80\u8c37 \u5fb9\uff1a\u4e2d\u54bd\u982d\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u7279\u5fb4\uff1a\u820c\u6241\u5e73\u4e0a\u76ae\u764c\u3068\u306e\u6bd4\u8f03. \u7b2c32\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u6771\u4eac\uff092008\u5e746\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u95a2\u7bc0\u8154\u306b\u591a\u91cf\u306e\u904a\u96e2\u4f53\u3092\u8a8d\u3081\u305f\u984e\u95a2\u7bc0\u6ed1\u819c\u6027\u9aa8\u8edf\u9aa8\u816b\u75c7\u306e1\u4f8b. \u7b2c21\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092008\u5e747\u6708 \u6284\u9332P127 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c20\u5dfbSuppl. Page127(2008.07)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u6025\u6027\u5316\u81bf\u6027\u984e\u95a2\u7bc0\u708e\u306e1\u4f8b. \u7b2c21\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092008\u5e747\u6708 \u6284\u9332P144 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c20\u5dfbSuppl. Page144(2008.07)<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u5927\u5185 \u5b66, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u6b63\u4e2d\u304a\u3088\u3073\u4e21\u5074\u95a2\u7bc0\u7a81\u8d77\u9aa8\u6298\u306b\u3088\u308a\u95a2\u7bc0\u9838\u90e8\u306e\u5916\u5074\u8ee2\u4f4d\u3092\u751f\u3058\u305f\u5c0f\u5150\u9aa8\u6298\u306e1\u4f8b. \u7b2c10\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092008\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b77\u5dfb1\u53f7 Page33(2008.06)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u660e, \u9ed2\u5d8b \u4f38\u4e00\u90ce, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u7c89\u7815\u9aa8\u6298\u306e\u6cbb\u7642\u7d4c\u9a13. \u7b2c10\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092008\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b77\u5dfb1\u53f7 Page35-36(2008.06)<\/p>\n\n\n\n

\u938c\u7530 \u5353, \u912d \u6f22\u5fe0, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247\uff1a\u30b9\u30dd\u30fc\u30c4\u5916\u50b7\u306b\u3088\u308b\u984e\u9854\u9762\u9aa8\u6298\u306e\u691c\u8a0e. \u7b2c19\u56de\u65e5\u672c\u30b9\u30dd\u30fc\u30c4\u6b6f\u79d1\u533b\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092008\u5e747\u6708 \u65e5\u672c\u30b9\u30dd\u30fc\u30c4\u6b6f\u79d1\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u6284\u9332\u96c619\u56de Page113(2008.07)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u81ea\u767a\u6027\u7570\u5e38\u5473\u899a\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c23\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\uff08\u6771\u4eac\uff092008\u5e747\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c23\u5dfb1-2\u53f7 Page74(2008.12)<\/p>\n\n\n\n

Watari F, Akasaka T, Ishikawa K, Matuoka M, Hirata E, Terada M, Yokoyama A, Uo M, Itoh S, Yawaka Y, Suzuki M, Takashi N, Totsuka Y, Kitagawa Y, Abe S, Rosca ID, Kuboki Y and Bando Y : Various nanotube scaffolds for cell proliferation. The 10TH International Symposium on Multiscale, Multifunctional and Functionally Graded Materials (Sendai), 2008.9<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a\u7fa9\u6b6f\u306b\u5b9a\u7740\u3057\u305f\u30ab\u30f3\u30b8\u30c0\u83cc\u306b\u5bfe\u3059\u308b\u30aa\u30be\u30f3\u6c34\u306e\u9664\u83cc\u52b9\u679c. \u7b2c18\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092008\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c14\u5dfb2\u53f7 Page63(2008.12)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f, \u6751\u7530 \u7ffc, \u4e0a\u5742 \u514b\u5f66, \u5927\u7530 \u6d0b\u4e8c\u90ce\uff1a\u81b5\u982d\u5341\u4e8c\u6307\u8178\u5207\u9664\u5f8c\u3001\u5473\u899a\u969c\u5bb3\u3092\u4f34\u3046\u8457\u3057\u3044\u4e9c\u925b\u6b20\u4e4f\u75c7\u306e1\u4f8b. \u7b2c18\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092008\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c14\u5dfb2\u53f7 Page82(2008.12)<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u591a\u5c64\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3092\u30b3\u30e9\u30fc\u30b2\u30f3\u30b3\u30fc\u30c8\u30c7\u30a3\u30c3\u30b7\u30e5\u306b\u30b3\u30fc\u30c8\u3057\u305f\u7d30\u80de\u57f9\u990a\u62c5\u4f53\u306e\u958b\u767a\u3068\u91d1\u5c5e\u3078\u306e\u5fdc\u7528. \u7b2c52\u56de\u65e5\u672c\u6b6f\u79d1\u7406\u5de5\u5b66\u4f1a\u5b66\u8853\u8b1b\u6f14\u4f1a\uff08\u5927\u962a\uff092008\u5e749\u6708 \u6b6f\u79d1\u6750\u6599\u30fb\u5668\u68b027\u5dfb5\u53f7 Page430(2008.09)\u3000<\/p>\n\n\n\n

\u8fd1\u85e4 \u4fe1\u592b, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f, \u65b0\u85e4 \u6b63\u4fe1, \u4e80\u5c71 \u5eb7\u6c38, \u516b\u4ee3 \u8015\u5150, \u795e\u8c37 \u771f\u5b50\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308bSPRR1B\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u6291\u5236\u3068\u305d\u306e\u7d30\u80de\u751f\u7269\u5b66\u7684\u306a\u610f\u7fa9. \u7b2c50\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092008\u5e749\u6708 Journal of Oral Biosciences50\u5dfbSuppl. Page133(2008.09)<\/p>\n\n\n\n

\u592a\u5b50 \u82b3\u4ec1, \u9ed2\u5d8b \u4f38\u4e00\u90ce, \u571f\u9580 \u5353\u6587, \u5409\u7530 \u91cd\u5149, \u5317\u5ddd \u5584\u653f\uff1a\u30d2\u30c8\u820c\u30ea\u30f3\u30d1\u7ba1\u306b\u304a\u3051\u308bToll-like receptor 2\u304a\u3088\u30734\u306e\u767a\u73fe. \u7b2c50\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092008\u5e749\u6708 Journal of Oral Biosciences50\u5dfbSuppl. Page197(2008.09)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u6749\u6d66 \u5343\u5c0b, \u5317\u68ee \u6b63\u543e, \u4f50\u85e4 \u660e, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u8edf\u53e3\u84cb\u539f\u767a\u795e\u7d4c\u5185\u5206\u6ccc\u578b\u5c0f\u7d30\u80de\u764c\u306e1\u4f8b. \u7b2c53\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5fb3\u5cf6\uff092008\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c54\u5dfbSuppl. Page78(2008.09)<\/p>\n\n\n\n

\u5927\u4e45\u4fdd \u76f4\u767b, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30e9\u30c3\u30c8\u6b6f\u5468\u9771\u5e2f\u7531\u6765\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u304c\u6709\u3059\u308b\u8840\u7ba1\u69cb\u7bc9\u80fd\u529b\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066. \u7b2c53\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5fb3\u5cf6\uff092008\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c54\u5dfbSuppl. Page94(2008.09)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u79cb\u5c71 \u771f\u5fd7, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u63a5\u5408\u90e8\u578b\u5148\u5929\u6027\u8868\u76ae\u6c34\u75b1\u75c7\u306b\u304a\u3051\u308b\u30a8\u30ca\u30e1\u30eb\u8cea\u5f62\u6210\u4e0d\u5168\u306e\u767a\u75c7\u6a5f\u5e8f\u306e\u89e3\u6790. \u7b2c53\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5fb3\u5cf6\uff092008\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c54\u5dfbSuppl. Page119(2008.09)<\/p>\n\n\n\n

\u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u91ce\u8c37 \u5065\u4e00, \u5c71\u5d0e \u88d5, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0a\u984e\u524d\u6b6f\u90e8\u306b\u751f\u3058\u305f\u6b6f\u539f\u6027\u7dda\u7dad\u816b\u306e\u4e00\u4f8b. \u7b2c53\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\uff08\u5fb3\u5cf6\uff092008\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c54\u5dfbSuppl. Page190(2008.09)<\/p>\n\n\n\n

Watari F, Akasaka T, Terada M, Uo M, Ishikawa K, Matuoka M, Kuboki Y, Hirata E, Yokoyama A, Itoh S, Yawaka Y, Totsuka Y, Kitagawa Y, Abe S and Suzuki M : Cell Culture on Nanotube Scaffolds for Implant application. 4th Max Bergmann Symposium (Dresden)\uff0c2008.11<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u4e45\u4fdd\u6728 \u82b3\u5fb3\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u306e\u30c8\u30ea\u30d7\u30eb\u3078\u30ea\u30c3\u30af\u30b9\u69cb\u9020\u3068\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3068\u306e\u53cd\u5fdc. \u5317\u5927\u82e5\u624b\u7814\u7a76\u8005\u306e\u4f1a \u7b2c\uff11\u56de\u7814\u7a76\u4ea4\u6d41\u4f1a\uff08\u672d\u5e4c\uff092008\u5e7411\u6708<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u306e\u7d30\u80de\u57f9\u990a\u62c5\u4f53\u304a\u3088\u3073\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u6750\u6599\u8868\u9762\u6539\u8cea\u3078\u306e\u5fdc\u7528. \u5e73\u621020\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5927\u4f1a\uff08\u672d\u5e4c\uff092008\u5e7412\u6708<\/p>\n\n\n\n

\u592a\u5b50 \u82b3\u4ec1\uff1a\u30d2\u30c8\u820c\u30ea\u30f3\u30d1\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u304a\u3051\u308bCCL21, TLR2\u306a\u3089\u3073\u306bTLR4\u306e\u767a\u73fe. \u5e73\u621020\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5927\u4f1a\uff08\u672d\u5e4c\uff092008\u5e7412\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c29\u5dfb2\u53f7 Page271(2008.12)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9\uff1a\u63a5\u5408\u90e8\u578b\u5148\u5929\u6027\u8868\u76ae\u6c34\u75b1\u75c7\u306b\u304a\u3051\u308b\u30a8\u30ca\u30e1\u30eb\u8cea\u5f62\u6210\u4e0d\u5168\u306e\u767a\u75c7\u6a5f\u5e8f\u306e\u89e3\u6790. \u5e73\u621020\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5927\u4f1a\uff08\u672d\u5e4c\uff092008\u5e7412\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c29\u5dfb2\u53f7 Page272(2008.12)<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba\uff1a\u512a\u6027\u963b\u5bb3\u6027p53\u5909\u7570\u4f53R248Q\u306fH1299\u7d30\u80de\u306e\u6d78\u6f64\u80fd\u3092\u5897\u5927\u3055\u305b\u308b. \u5e73\u621020\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5927\u4f1a\uff08\u672d\u5e4c\uff092008\u5e7412\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c29\u5dfb2\u53f7 Page272(2008.12)<\/p>\n\n\n\n

\u6c38\u4e95 \u5eb7\u4e00, \u6b66\u7530 \u5b8f\u53f8, \u4e2d\u5ddd \u5b8f\u6cbb, \u6d45\u9999 \u6b63\u535a, \u5317\u5ddd \u5584\u653f: HSC-2\u7d30\u80de\u306e\u708e\u75c7\u53cd\u5fdc\u306b\u304a\u3051\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u904a\u8d70\u963b\u6b62\u56e0\u5b50\u306e\u5f79\u5272\u306b\u3064\u3044\u3066. \u5e73\u621020\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5927\u4f1a\uff08\u672d\u5e4c\uff092008\u5e7412\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c \u7b2c30\u5dfb\u7b2c1\u53f7 Page69\uff082009.06\uff09<\/p>\n\n\n\n

\u5e73\u621021\u5e74\uff082009\u5e74\uff09<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u4fdd\u5b58\u7684\u9838\u90e8\u90ed\u6e05\u8853\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c27\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\uff08\u6803\u6728\uff092009\u5e741\u6708 \u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u8a8c21\u5dfb4\u53f7 Page318(2009.12)<\/p>\n\n\n\n

\u4e45\u4fdd\u6728 \u82b3\u5fb3, \u5c3e\u95a2 \u548c\u79c0, \u6edd\u7530 \u88d5\u5b50, \u5bfa\u7530 \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u963f\u90e8 \u85ab\u660e, \u5b87\u5c3e \u57fa\u5f18, \u4e98\u7406 \u6587\u592b\uff1a\u8c9d\u3068\u9aa8\u306e\u5bc6\u63a5\u306a\u95a2\u4fc2\u3000\u30a2\u30b3\u30e4\u8c9d\u6bbb\u4f53\u304b\u3089\u306e\u9aa8\u82bd\u7d30\u80de\u306e\u6210\u9577\u56e0\u5b50(SDGF)\u306e\u5206\u96e2\u7cbe\u88fd\u3068\u8c9d\u7531\u6765\u300c\u30d0\u30a4\u30aa\u30a2\u30d1\u30bf\u30a4\u30c8\u300d\u306e\u5275\u88fd. \u7b2c21\u56de\u4ee3\u7528\u81d3\u5668\u30fb\u518d\u751f\u533b\u5b66\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092009\u5e741\u6708 \u5317\u6d77\u9053\u5916\u79d1\u96d1\u8a8c54\u5dfb1\u53f7 Page75(2009.06)<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u591a\u5c64\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3092\u30b3\u30e9\u30fc\u30b2\u30f3\u30b3\u30fc\u30c8\u30c7\u30a3\u30c3\u30b7\u30e5\u306b\u30b3\u30fc\u30c8\u3057\u305f\u7d30\u80de\u57f9\u990a\u62c5\u4f53\u306e\u958b\u767a\u3068\u91d1\u5c5e\u3078\u306e\u5fdc\u7528. \u539a\u751f\u52b4\u50cd\u79d1\u5b66\u7814\u7a76\u8cbb\u88dc\u52a9\u91d1\u3000\u5316\u5b66\u7269\u8cea\u30ea\u30b9\u30af\u7814\u7a76\u4e8b\u696d \u30ca\u30ce\u5fae\u7c92\u5b50\u306e\u4f53\u5185\u52d5\u614b\u53ef\u8996\u6cd5\u306e\u958b\u767a \u5e73\u621020\u5e74\u5ea6\u51ac\u5b63 \u7b2c5\u56de\u76ee\u6a19\u7b56\u5b9a\u7814\u7a76\u767a\u8868\u4f1a\uff08\u82eb\u5c0f\u7267\uff092009\u5e742\u6708<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u77ef\u6b63\u6b6f\u79d1\u6cbb\u7642\u306b\u5fc5\u8981\u306a\u533b\u7642\u9762\u63a5\u6280\u6cd5\u3000\u60a3\u8005\u3055\u3093\u306e\u4e0d\u5b89\u306e\u898b\u3064\u3051\u65b9\u3001\u53d6\u308a\u9664\u304d\u65b9. \u5e73\u621022\u5e74\u5ea6\u65e5\u672c\u81e8\u5e8a\u77ef\u6b63\u6b6f\u79d1\u533b\u4f1a2\u6708\u4f8b\u4f1a\u2015\u5317\u6d77\u9053\u4f8b\u4f1a\u2015\uff08\u672d\u5e4c\uff092009\u5e742\u6708 \u65e5\u672c\u81e8\u5e8a\u77ef\u6b63\u6b6f\u79d1\u533b\u4f1a\u96d1\u8a8c23\u5dfb1\u53f7 Page33-34(2011.10)<\/p>\n\n\n\n

Uo M, Terada M, Akasaka T, Kitagawa Y, Watri F\uff1aCarbon nanotubes\/collagen composite for biomedical applications\uff0eHybrid Materials 2009 (Tours), 2009.3<\/p>\n\n\n\n

\u4e98\u7406 \u6587\u592b, \u8d64\u5742 \u53f8, \u5bfa\u7530 \u5178\u5b50, \u8d8a\u5ddd \u9ad8\u5149, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f\uff1a\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u4e0a\u306e\u7d30\u80de\u57f9\u990a. \u8868\u9762\u6280\u8853\u5354\u4f1a \u7b2c119\u56de\u8b1b\u6f14\u5927\u4f1a\uff08\u5c71\u68a8\uff092009\u5e743\u6708<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u660e, \u6749\u6d66 \u5343\u5c0b, \u4f50\u85e4 \u6df3, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u6885\u672c \u7d18\u5b50, \u5317\u68ee \u6b63\u543e, \u5317\u5ddd \u5584\u653f\uff1a\u96e3\u6cbb\u6027\u306e\u4e0b\u984e\u9aa8\u9aa8\u9ac4\u708e\u306b\u5bfe\u3059\u308bFDG-PET\u306e\u6709\u7528\u6027\u306e\u691c\u8a0e. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page198-199(2009.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u6cbb\u7642\u524d\u306e\u75bc\u75db\u306b\u95a2\u9023\u3059\u308b\u56e0\u5b50\u306e\u7814\u7a76(\u7b2c\u56db\u5831)\u3000\u820c\u764c\u306e\u81ea\u767a\u75db\u306b\u9650\u5b9a\u3057\u3066\u306e\u691c\u8a0e. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u6284\u9332P210<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u4e2d\u6751 \u88d5\u4ecb, \u5f8c\u85e4 \u96bc, \u5927\u5185 \u5b66, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u4e88\u9632\u306b\u304a\u3051\u308b\u7fa9\u6b6f\u3078\u306e\u5bfe\u51e6\u3000\u57f9\u990a\u691c\u67fb\u306b\u3088\u308b\u30aa\u30be\u30f3\u6c34\u306e\u7fa9\u6b6f\u6d17\u6d44\u52b9\u679c. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page217(2009.09)<\/p>\n\n\n\n

\u6885\u672c \u7d18\u5b50, \u91d1\u7530 \u6cf0\u5e78, \u6749\u6d66 \u5343\u5c0b, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0a\u984e\u9aa8\u306b\u751f\u3058\u305f\u817a\u816b\u69d8\u6b6f\u539f\u6027\u816b\u760d\u306e1\u4f8b. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page226-227(2009.09)<\/p>\n\n\n\n

\u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u660e, \u5c0f\u91ce \u8ca2\u4f38, \u6238\u585a \u9756\u5247, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u982d\u9838\u90e8\u9818\u57df\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u306e\u60aa\u6027\u5ea6\u8a55\u4fa1\u306b\u304a\u3051\u308bFDG-PET\u304a\u3088\u3073sIL-2R\u306e\u6709\u7528\u6027\u306e\u691c\u8a0e. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page264-265(2009.09)<\/p>\n\n\n\n

\u6c38\u4e95 \u5eb7\u4e00, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1aHSC-2\u7d30\u80de\u306e\u708e\u75c7\u53cd\u5fdc\u306b\u304a\u3051\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u904a\u8d70\u963b\u6b62\u56e0\u5b50\u306e\u5f79\u5272\u306b\u3064\u3044\u3066. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page267(2009.09)<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u5317\u5ddd \u5584\u653f\uff1a\u512a\u6027\u963b\u5bb3\u6027p53\u5909\u7570\u4f53R248Q\u3001R248W\u306eH1299\u7d30\u80de\u306b\u304a\u3051\u308b\u7d30\u80de\u751f\u7269\u5b66\u7684\u691c\u8a0e. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u6284\u9332P292 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page268(2009.09)<\/p>\n\n\n\n

\u592a\u5b50 \u82b3\u4ec1, \u5c71\u5d0e \u88d5, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u30d2\u30c8\u820c\u30ea\u30f3\u30d1\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u304a\u3051\u308bCCL21\u3001TLR2\u306a\u3089\u3073\u306bTLR4\u306e\u767a\u73fe. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page273-274(2009.09)<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u591a\u5c64\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3092\u30b3\u30e9\u30fc\u30b2\u30f3\u306b\u30b3\u30fc\u30c8\u3057\u305f\u7d30\u80de\u57f9\u990a\u62c5\u4f53\u306e\u958b\u767a. \u7b2c63\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6d5c\u677e\uff092009\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c58\u5dfb4\u53f7 Page275-276(2009.09)<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u4f50\u85e4 \u5065\u5f66, \u6751\u897f \u4eac\u4e00\u90ce, \u5317\u5ddd \u6804\u4e8c, \u5317\u5ddd \u5584\u653f\uff1a\u6297\u30ea\u30f3\u8102\u8cea\u6297\u4f53\u75c7\u5019\u7fa4\u60a3\u8005\u306e\u629c\u6b6f\u7d4c\u9a13. \u7b2c18\u56de\u65e5\u672c\u6709\u75c5\u8005\u6b6f\u79d1\u533b\u7642\u5b66\u4f1a\u7dcf\u4f1a\uff08\u677e\u672c\uff092009\u5e744\u6708 \u6709\u75c5\u8005\u6b6f\u79d1\u533b\u764218\u5dfb3\u53f7 Page247-248(2009.12)<\/p>\n\n\n\n

Hata H, Yamazaki Y, Takinami S, Kanegae K, Kuge Y, Tamaki N, Kitagawa Y : Usefulness of FDG-PET in diagnosis and management for refractory osteonecrosis of jaws. 2009 SNM Annual Meeting (Tronto), 2009.6<\/p>\n\n\n\n

\u677e\u6d66 \u591a\u559c\u5b50, \u4e2d\u6751 \u7f8e\u559c\u5b50, \u5317\u5ddd \u5584\u653f, \u5e73\u7530 \u8015\u5e73, \u4f50\u91ce \u548c\u751f\uff1a\u591a\u6570\u6b6f\u6b20\u640d\u3092\u4f34\u3046\u4e0b\u984e\u524d\u7a81\u75c7\u4f8b\u306b\u304a\u3051\u308b\u5916\u79d1\u7684\u77ef\u6b63\u6642\u306e\u984e\u4f4d\u6c7a\u5b9a\u306a\u3089\u3073\u306b\u5b89\u5b9a\u306b\u5bfe\u3059\u308b\u5de5\u592b. \u7b2c19\u56de\u65e5\u672c\u984e\u5909\u5f62\u75c7\u5b66\u4f1a\u7dcf\u4f1a\uff08\u4ed9\u53f0\uff092009\u5e746\u6708 \u65e5\u672c\u984e\u5909\u5f62\u75c7\u5b66\u4f1a\u96d1\u8a8c19\u5dfb2\u53f7 Page120(2009.05)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u75db\u75c7\u3068\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306e\u5408\u4f75\u75c7\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c24\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\uff08\u6771\u4eac\uff092009\u5e746\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c24\u5dfb2\u53f7 Page90(2009.12)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u75db\u75c7\u3068\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306e\u5408\u4f75\u75c7\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c1\u56de\u65e5\u672c\u5fc3\u8eab\u533b\u5b665\u5b66\u4f1a\u5408\u540c\u96c6\u4f1a\uff08\u6771\u4eac\uff092009\u5e746\u6708 \u5fc3\u8eab\u533b\u5b6649\u5dfb6\u53f7 Page600(2009.06)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u79e6 \u6d69\u4fe1, \u5317\u68ee \u6b63\u543e, \u4f50\u85e4 \u660e, \u6749\u6d66 \u5343\u5c0b, \u91ce\u8c37 \u5065\u4e00, \u7b95\u8f2a \u548c\u884c, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u982c\u30ea\u30f3\u30d1\u7bc0\u53ca\u3073\u4e0b\u984e\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3092\u304d\u305f\u3057\u305f\u982c\u7c98\u819c\u764c\u306e\u4e00\u4f8b. \u7b2c35\u56de\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u65ed\u5ddd\uff092009\u5e746\u6708<\/p>\n\n\n\n

\u6885\u672c \u7d18\u5b50, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u4f50\u85e4 \u660e, \u77f3\u5ddd \u8aa0, \u91ce\u8c37 \u5065\u4e00, \u7b95\u8f2a \u548c\u884c, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0a\u984e\u9aa8\u306b\u751f\u3058\u305fmyxofibrosarcoma\u306e1\u4f8b. \u7b2c 35 \u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u65ed\u5ddd\uff092009\u5e746\u6708<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u767e\u5408\u8349 \u5065\u572d\u5fd7, \u9038\u898b \u4ec1, \u8d64\u6839 \u5149\u5ba3, \u8305\u91ce \u4fee\u53f2, \u6c38\u677e \u5c06\u543e, \u4e0a\u689d \u670b\u4e4b, \u98ef\u7530 \u5584\u5e78, \u5177 \u82b3\u660e, \u5927\u66f2 \u8cb4\u592b, \u9b3c\u585a \u54f2\u90ce, \u4e2d\u5ddd \u96c5\u88d5, \u5927\u7530 \u6d0b\u4e8c\u90ce\uff1a\u5f53\u9662\u3067\u306e\u4e0b\u984e\u9aa8\u518d\u5efa\u75c7\u4f8b\u306b\u304a\u3051\u308b\u8853\u5f8c\u5408\u4f75\u75c7\u306b\u3064\u3044\u3066\u306e\u691c\u8a0e. \u7b2c33\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u672d\u5e4c\uff092009\u5e746\u6708<\/p>\n\n\n\n

\u6751\u4e95 \u77e5\u4f73, \u72ac\u4f0f \u6b63\u5e78, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f, \u4f50\u8cc0 \u6052\u592b\uff1a\u30d2\u30c8Na+\/I-\u5171\u8f38\u9001\u86cb\u767d(hNIS)\u907a\u4f1d\u5b50\u3092\u5229\u7528\u3057\u305f\u65b0\u3057\u3044\u764c\u306ein vivo\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u6cd5\u306e\u958b\u767a. \u7b2c33\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c30\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092009\u5e746\u6708 \u982d\u9838\u90e8\u764c35\u5dfb2\u53f7 Page182(2009.05)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u6751\u4e95 \u77e5\u4f73, \u4e2d\u6751 \u88d5\u4ecb, \u4eca\u5f85 \u8ce2\u6cbb, \u5317\u5ddd \u5584\u653f, \u672c\u9593 \u660e\u5b8f, \u7027 \u91cd\u6210, \u6298\u8218 \u4f38\u5f66, \u798f\u7530 \u8aed, \u6589\u85e4 \u4eae, \u53e4\u5ddd \u6d0b\u5fd7, \u5c71\u672c \u6709\u5e73, \u95a2\u5802 \u5145\uff1a\u982d\u9838\u90e8\u764c\u6cbb\u7642\u306b\u304a\u3051\u308b\u53e3\u8154\u30b1\u30a2\u306e\u5b9f\u969b \u982d\u9838\u90e8\u9032\u884c\u764c\u306b\u5bfe\u3059\u308b\u518d\u5efa\u624b\u8853\u306e\u5408\u4f75\u75c7\u6e1b\u5c11\u306b\u53e3\u8154\u30b1\u30a2\u306f\u5bc4\u4e0e\u3059\u308b\u304b. \u7b2c33\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c30\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092009\u5e746\u6708 \u982d\u9838\u90e8\u764c35\u5dfb2\u53f7 Page71(2009.05)<\/p>\n\n\n\n

\u6817\u6797 \u548c\u4ee3, \u5c0f\u91ce \u8ca2\u4f38, \u8db3\u5229 \u96c4\u4e00, \u5927\u5ee3 \u6d0b\u4e00, \u912d \u6f22\u5fe0, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247\uff1a\u4e0b\u984e\u6b6f\u8089\u6241\u5e73\u4e0a\u76ae\u764c\u624b\u8853\u75c7\u4f8b\u306e\u6cbb\u7642\u6210\u7e3e\u306e\u691c\u8a0e. \u7b2c33\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c30\u56de\u982d\u9838\u90e8\u624b\u8853\u624b\u6280\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092009\u5e746\u6708 \u982d\u9838\u90e8\u764c35\u5dfb2\u53f7 Page127(2009.05)<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u65e5\u672c\u306e\u6b6f\u5b66\u6559\u80b2\u306b\u304a\u3051\u308b\u53e3\u8154\u5185\u79d1\u5b66\u306e\u4f4d\u7f6e\u3065\u3051\u3000\u5317\u5927\u3067\u306e\u53d6\u308a\u7d44\u307f. \u7b2c22\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c19\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u8449\u5c71\uff092009\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page363(2009.10) \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c15\u5dfb2\u53f7 Page91(2009.12)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5f8c\u85e4 \u96bc, \u5927\u5185 \u5b66, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a20\u6b73\u4ee3\u306e\u6b6f\u5b66\u90e8\u5b66\u751f\u306b\u304a\u3051\u308b\u30ab\u30f3\u30b8\u30c0\u83cc\u306e\u4fdd\u83cc\u72b6\u6cc1\u306b\u3064\u3044\u3066. \u7b2c19\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u8449\u5c71\uff092009\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c15\u5dfb2\u53f7 Page119(2009.12)<\/p>\n\n\n\n

\u4e45\u4fdd\u6728 \u82b3\u5fb3, \u5bfa\u7530 \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u6edd\u7530 \u88d5\u5b50, \u658e\u85e4 \u5f70, \u9ad8\u5c71 \u6e80\u5229\u5b50, \u8cc0\u6765 \u4ea8\uff1a\u4eba\u5de5ECM\u306e\u5e7e\u4f55\u5b66\u3000\u9aa8\u30fb\u8840\u7ba1\u3092\u8a98\u5c0e\u3059\u308b\u300c\u30c8\u30f3\u30cd\u30eb\u69cb\u9020\u300d\u3068\u6700\u9069\u9aa8\u5f62\u6210\u7a7a\u9593\u306e\u8ffd\u7a76. \u7b2c27\u56de\u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092009\u5e747\u6708 \u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u6284\u9332\u96c627\u56de Page202(2009.07)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u8840\u884c\u6027\u611f\u67d3\u306e\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u305f\u6025\u6027\u5316\u81bf\u6027\u984e\u95a2\u7bc0\u5468\u56f2\u708e\u306e1\u4f8b. \u7b2c22\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092009\u5e747\u6708 \u6284\u9332P132 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c21\u5dfbSuppl. Page132(2009.07)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5317\u68ee \u6b63\u543e, \u4f50\u85e4 \u660e, \u6749\u6d66 \u5343\u5c0b, \u79e6 \u6d69\u4fe1, \u963f\u90e8 \u8cb4\u6d0b, \u7af9\u5185 \u5eb7\u4eba, \u539f \u535a\u5fd7, \u91d1\u7530 \u6cf0\u5e78, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u524d\u5ead\u306b\u6b6f\u7259\u8ff7\u5165\u3092\u8a8d\u3081\u305f\u53e3\u8154\u5916\u50b7\u306e1\u4f8b. \u7b2c11\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b78\u5dfb1\u53f7 Page31(2009.06)<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u5317\u7530 \u79c0\u662d, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u4e09\u4e0a \u7d17\u5b63, \u5c71\u53e3 \u6cf0\u5f66\uff1a\u8840\u7ba1\u67c4\u4ed8\u304d\u8153\u9aa8\u76ae\u5f01\u306b\u3088\u308b\u5168\u4e0b\u984e\u9aa8\u306e\u518d\u5efa\u3092\u884c\u3063\u305f\u984e\u9854\u9762\u640d\u50b7\u75c7\u4f8b\u306b\u304a\u3051\u308b\u8853\u5f8c\u7d4c\u904e. \u7b2c11\u56de\u65e5\u672c\u53e3\u8154\u5b66\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b78\u5dfb1\u53f7 Page30(2009.06)<\/p>\n\n\n\n

\u5c0f\u5800 \u5584\u5247, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1a\u30b9\u30dd\u30fc\u30c4\u5916\u50b7\u306b\u3088\u308b\u984e\u9854\u9762\u9aa8\u6298\u306e\u691c\u8a0e. \u7b2c11\u56de\u65e5\u672c\u53e3\u8154\u5b66\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b78\u5dfb1\u53f7 Page33(2009.06)<\/p>\n\n\n\n

\u698a\u539f \u5178\u5e78, \u6c34\u91ce \u8cb4\u884c, \u7554\u7530 \u8ca2, \u4e2d\u6751 \u7950\u4ecb, \u7b95\u8f2a \u548c\u884c\uff1a\u30ac\u30e9\u30b9\u7247\u306b\u3088\u308b\u5916\u56fd\u4eba\u65c5\u884c\u8005\u306e\u981a\u90e8\u30fb\u5589\u982d\u30fb\u54bd\u982d\u5916\u50b7\u306e1\u4f8b. \u7b2c11\u56de\u65e5\u672c\u53e3\u8154\u5b66\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e747\u6708<\/p>\n\n\n\n

\u5927\u4e45\u4fdd \u76f4\u767b, \u7530\u6751 \u6b63\u4eba, \u98ef\u585a \u6b63, \u52a0\u8302 \u653f\u6674, \u5ba2\u672c \u6589\u5b50, \u5e16\u4f50 \u76f4\u5e78, \u9ad8\u6a4b \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u77f3\u5d0e \u660e\uff1a\u6b6f\u6839\u819c\u7531\u6765\u5e79\u7d30\u80de\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u30de\u30fc\u30ab\u30fc\u967d\u6027\u8840\u7ba1\u69cb\u9020\u306e\u5f62\u6210. \u7b2c18\u56de\u786c\u7d44\u7e54\u518d\u751f\u751f\u7269\u5b66\u4f1a\uff08\u672d\u5e4c\uff092009\u5e749\u6708 Journal of Oral Biosciences51\u5dfbSuppl. Page68(2009.08)<\/p>\n\n\n\n

\u5927\u4e45\u4fdd \u76f4\u767b, \u7530\u6751 \u6b63\u4eba, \u98ef\u585a \u6b63, \u52a0\u8302 \u653f\u6674, \u5ba2\u672c \u6589\u5b50, \u5e16\u4f50 \u76f4\u5e78, \u9ad8\u6a4b \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u77f3\u5d0e \u660e\uff1a\u6b6f\u6839\u819c\u7531\u6765\u5e79\u7d30\u80de\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u30de\u30fc\u30ab\u30fc\u967d\u6027\u8840\u7ba1\u69cb\u9020\u306e\u5f62\u6210. \u7b2c51\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u65b0\u6f5f\uff092009\u5e749\u6708 Journal of Oral Biosciences51\u5dfbSuppl. Page103(2009.08)<\/p>\n\n\n\n

\u5f8c\u85e4 \u96bc, \u9053\u5ff5 \u6b63\u6a39, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f, \u67f4\u7530 \u5065\u4e00\u90ce\uff1a\u53e3\u8154\u75be\u60a3\u3092\u6709\u3059\u308b\u60a3\u8005\u306e\u672b\u68a2\u8840\u5358\u6838\u7403\u306b\u304a\u3051\u308bToll\u69d8\u53d7\u5bb9\u4f53\u306e\u767a\u73fe. \u7b2c51\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u65b0\u6f5f\uff092009\u5e749\u6708 Journal of Oral Biosciences51\u5dfbSuppl. Page87(2009.08)<\/p>\n\n\n\n

Sato J, Goto J, Harahashi A, Yamazaki Y, Satoh A, Notani K, Kitagawa Y : Oral health care reduces the risk of postoperative wound infection in patients with oral squamous cell carcinoma. 91th Annual Meeting, Scientific Sessions and Exhibition in conjunction with the Canadian Association of Oral and Maxillofacial Surgeons (Toronto), 2009.10 Abstract P69<\/p>\n\n\n\n

Inubushi M, Jin Y, Hata H, Murai C, Kitagawa Y, Tamaki N : Assessment of Hypoxia-Responsive Transcription Factors for Hypoxia-Targeting Imaging and Therapy. Annual Congress of the European Association of Nuclear Medicine (Barcelona), 2009.10<\/p>\n\n\n\n

Murai C, Inubushi M, Hata H, Jin Y, Shidahara M, Sogawa C, Tsuji A, Koizumi M, Kitagawa Y and Saga T : Radionuclide reporter gene imaging of mouse xenograft model of human colon cancer cell lines stably expressing human sodium-iodide Symporter (hNIS). 2009 Annual Congress of the European Association of Nuclear Medicine (Barcelona), 2009.10<\/p>\n\n\n\n

\u9ed2\u9808 \u62d3\u90ce, \u5927\u8cc0 \u5247\u5b5d, \u6771\u91ce \u53f2\u88d5, \u6a0b\u7530 \u6cf0\u6d69, \u683c\u53e3 \u6e09, \u9ed2\u5d8b \u96c4\u5fd7, \u79cb\u91ce \u6587\u81e3, \u77f3\u5ddd \u4fee\u5e73, \u79cb\u5c71 \u5ee3\u8f14, \u6238\u585a \u9756\u5247, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u304a\u3051\u308bHuR\u3092\u4ecb\u3057\u305fCOX-2\u53ca\u3073VEGFA mRNA\u306e\u767a\u73fe\u4ea2\u9032. \u7b2c68\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092009\u5e7410\u6708<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u6d5c\u7530 \u6df3\u4e00, \u4e80\u5c71 \u6b66\u5fd7, \u9234\u6728 \u53cb\u5e0c\u5b50, \u4f0a\u5ddd \u771f\u5f13, \u591a\u7530 \u5149\u5b8f, \u4e2d\u5ddd \u5b8f\u6cbb, \u5317\u5ddd \u5584\u653f, \u5b88\u5185 \u54f2\u4e5f\uff1aR248Q\u5909\u7570p53\u306b\u3088\u308bH1299\u7d30\u80de\u306e\u6d78\u6f64\u80fd\u5897\u5f37(p53 dominant-negative mutant R248Q promotes invasion of H1299 cells). \u7b2c68\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092009\u5e7410\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b68\u56de Page143(2009.08)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u963f\u90e8 \u8cb4\u6d0b, \u5317\u5ddd \u6804\u4e8c\uff1a\u5de8\u5927\u306a\u820c\u52d5\u9759\u8108\u5947\u5f62\u306e1\u4f8b. \u3000 \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708\u3000\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page110(2009.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u6749\u6d66 \u5343\u5c0b, \u5317\u5ddd \u5584\u653f, \u524d\u7530 \u61b2\u662d\uff1aHIV\/AIDS\u60a3\u8005\u306e\u6b6f\u79d1\u533b\u7642\u4f53\u5236\u306b\u95a2\u3059\u308b\u610f\u8b58\u8abf\u67fb\u306b\u3064\u3044\u3066. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u6284\u9332P86<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5317\u68ee \u6b63\u543e, \u5f8c\u85e4 \u96bc, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u553e\u6db2\u4e2d\u306eIL-6\u767a\u73fe\u306b\u3064\u3044\u3066\u306e\u691c\u8a0e(\u7b2c\u4e09\u5831)\u3000\u77ed\u671f\u7684\u4e88\u5f8c\u3068\u306e\u95a2\u9023. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u6284\u9332P118<\/p>\n\n\n\n

\u9ed2\u9808 \u62d3\u90ce, \u5927\u8cc0 \u5247\u5b5d, \u683c\u53e3 \u6e09, \u9ed2\u5d8b \u96c4\u5fd7, \u6238\u585a \u9756\u5247, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u304a\u3051\u308bHuR\u3092\u4ecb\u3057\u305fCOX2\u304a\u3088\u3073VEGF-A\u306emRNA\u306e\u767a\u73fe\u4ea2\u9032. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708<\/p>\n\n\n\n

\u683c\u53e3 \u6e09, \u9ed2\u5d8b \u96c4\u5fd7, \u9577\u8c37\u5ddd \u535a\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u6238\u585a \u9756\u5247\uff1aRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30afHuR\u306e\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u304c\u53e3\u8154\u304c\u3093\u306b\u53ca\u307c\u3059\u5f71\u97ff. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u4f50\u85e4 \u660e, \u79e6 \u6d69\u4fe1, \u963f\u90e8 \u8cb4\u6d0b, \u9ed2\u5d8b \u96c4\u5fd7, \u91ce\u8c37 \u5065\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u9aa8\u4e2d\u5fc3\u6027\u6b6f\u539f\u6027\u7dda\u7dad\u816b\u306e1\u4f8b. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page200(2009.09)<\/p>\n\n\n\n

\u592a\u5b50 \u82b3\u4ec1, \u4f50\u85e4 \u5343\u6674, \u5bfa\u7530 \u5178\u5b50, \u4f50\u85e4 \u6df3, \u5c71\u5d0e \u88d5, \u9032\u85e4 \u6b63\u4fe1, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u984e\u95a2\u7bc0\u6ed1\u819c\u6027\u9aa8\u8edf\u9aa8\u816b\u75c7\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page228(2009.09)<\/p>\n\n\n\n

\u5b87\u5c3e \u57fa\u5f18, \u5bfa\u7530 \u5178\u5b50, \u5317\u5ddd \u5584\u653f, \u99ac\u6e15 \u4e9c\u5e0c\u5b50, \u6238\u585a \u9756\u5247\uff1a\u91d1\u5c5e\u30a2\u30ec\u30eb\u30ae\u30fc\u60a3\u8005\u306e\u53e3\u8154\u5185\u91d1\u5c5e\u4fee\u5fa9\u7269\u306e\u8fc5\u901f\u6210\u5206\u5206\u6790. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page246(2009.09)<\/p>\n\n\n\n

\u5bfa\u7530 \u5178\u5b50, \u5b87\u5c3e \u57fa\u5f18, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u591a\u5c64\u30ab\u30fc\u30dc\u30f3\u30ca\u30ce\u30c1\u30e5\u30fc\u30d6\u3092\u7528\u3044\u305f\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u6750\u6599\u306e\u8868\u9762\u6539\u8cea\u3078\u306e\u5fdc\u7528. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page278(2009.09)<\/p>\n\n\n\n

\u5bae\u7530 \u52dd, \u5c71\u4e0b \u5fb9\u90ce, \u5c71\u7530 \u7950\u656c, \u5317\u5ddd \u5584\u653f, \u4eca\u4e95 \u88d5, \u4e0b\u90f7 \u548c\u96c4, \u5927\u5ca9 \u4f0a\u77e5\u90ce, \u7530\u4e2d \u7fa9\u5f18, \u4f0a\u6771 \u9686\u5229, \u798f\u7530 \u4ec1\u4e00, \u702c\u6238 \u304b\u3093\u4e00\uff1a\u75c5\u9662\u6b6f\u79d1\u53e3\u8154\u5916\u79d1\u306e\u8ab2\u984c\u3068\u5c55\u671b \u5168\u56fd\u75c5\u9662\u6b6f\u79d1\u53e3\u8154\u5916\u79d1\u3078\u306e\u30a2\u30f3\u30b1\u30fc\u30c8\u8abf\u67fb\u306e\u7d50\u679c. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page32(2009.09)<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u6d45\u9999 \u62d3\u54c9, \u5317\u5ddd \u6804\u4e8c, \u698a\u539f \u5178\u5e78, \u5317\u7530 \u79c0\u662d, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247\uff1a\u904a\u96e2\u76ae\u5f01\u306b\u3088\u308b\u984e\u53e3\u8154\u518d\u5efa\u75c7\u4f8b\u306e\u691c\u8a0e\u3000\u8907\u6570\u56de\u306e\u904a\u96e2\u7d44\u7e54\u79fb\u690d\u3092\u884c\u3063\u305f\u75c7\u4f8b\u306e\u554f\u984c\u70b9. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page58(2009.09)<\/p>\n\n\n\n

\u6d66\u51fa \u96c5\u88d5, \u7530\u4e2d \u5fb3\u662d, \u5d8b\u7530 \u6df3, \u67f4\u7530 \u8003\u5178, \u53e4\u6fa4 \u6e05\u6587, \u6850\u7530 \u5fe0\u662d, \u5c71\u672c \u54f2\u4e5f, \u6c60\u908a \u54f2\u90ce, \u5317\u5ddd \u5584\u653f, \u5009\u79d1 \u61b2\u6cbb, \u702c\u6238 \u304b\u3093\u4e00, \u798f\u7530 \u4ec1\u4e00\uff1a\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u306e\u5168\u56fd\u8abf\u67fb\u5831\u544a. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page65(2009.09)<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6075, \u67cf\u5d0e \u6674\u5f66, \u576a\u4e95 \u5bff\u5178, \u7b20\u5e2b \u4e45\u7f8e\u5b50, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f, \u4e95\u4e0a \u8fb2\u592b\u7537\uff1a\u540c\u7a2e\u9aa8\u9ac4\u79fb\u690d\u306b\u304a\u3051\u308b\u91cd\u75c7\u53e3\u5185\u708e\u767a\u75c7\u95a2\u9023\u56e0\u5b50\u306e\u691c\u8a0e. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page71(2009.09)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u6751\u7530 \u7ffc, \u5927\u5185 \u5b66, \u5f8c\u85e4 \u96bc, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306b\u304a\u3051\u308b\u518d\u767a\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5b66\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page85(2009.09)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u5c71\u5d0e \u88d5, \u6751\u4e95 \u77e5\u4f73, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u9aa8\u5185\u306b\u767a\u751f\u3057\u305f\u591a\u5f62\u817a\u816b\u306e1\u4f8b. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page134(2009.09)<\/p>\n\n\n\n

\u5c0f\u8fbb \u7d20\u5b50, \u4e2d\u6751 \u7f8e\u559c\u5b50, \u52dd\u7530 \u79c0\u884c, \u65b0\u7530 \u54f2\u4e5f, \u690d\u91ce \u9ad8\u7ae0, \u5317\u5ddd \u5584\u653f, \u4f50\u91ce \u548c\u751f\uff1a15\u5e74\u9593\u306b\u308f\u305f\u308bOral florid papillomatosis\u306e\u7d4c\u904e\u5831\u544a. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092009\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c55\u5dfbSuppl. Page197(2009.09)<\/p>\n\n\n\n

\u6751\u4e95 \u77e5\u4f73, \u72ac\u4f0f \u6b63\u5e78, \u5fd7\u7530\u539f \u7f8e\u4fdd, \u8fbb \u539a\u81f3, \u5c0f\u6cc9 \u6e80, \u5317\u5ddd \u5584\u653f, \u4f50\u8cc0 \u6052\u592b\uff1a\u30d2\u30c8Na+\/I-\u5171\u8f38\u9001\u86cb\u767d(hNIS)\u907a\u4f1d\u5b50\u5b89\u5b9a\u767a\u73fe\u5927\u8178\u764c\u7d30\u80de\u682a\u30de\u30a6\u30b9\u62c5\u764c\u30e2\u30c7\u30eb\u306e\u30ec\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0. \u7b2c49\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u65ed\u5ddd\uff092009\u5e7410\u6708 \u6838\u533b\u5b6646\u5dfb3\u53f7 Page279(2009.09)<\/p>\n\n\n\n

\u524d\u7530 \u61b2\u662d, \u7684\u91ce \u6176, \u5317\u5ddd \u5584\u653f, \u4f50\u85e4 \u6df3, \u5c71\u53e3 \u6cf0, \u6c60\u7530 \u6b63\u4e00, \u67ff\u6fa4 \u5353, \u7530\u4e0a \u6b63, \u9ad8\u6728 \u5f8b\u7537, \u6c60\u91ce \u826f, \u6fa4\u6728 \u4f73\u5f18, \u5bae\u7530 \u52dd, \u9023 \u5229\u9686, \u5409\u91ce \u5b8f, \u5409\u5ddd \u535a\u653f, \u6e9d\u90e8 \u6f64\u5b50, \u4e2d\u5ddd \u88d5\u7f8e\u5b50\uff1aHIV\u611f\u67d3\u60a3\u8005\u306e\u6b6f\u79d1\u8a3a\u7642\u5b9f\u614b\u8abf\u67fb. \u7b2c23\u56de\u65e5\u672c\u30a8\u30a4\u30ba\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7dcf\u4f1a\uff08\u540d\u53e4\u5c4b\uff092009\u5e7411\u6708 \u65e5\u672c\u30a8\u30a4\u30ba\u5b66\u4f1a\u8a8c11\u5dfb4\u53f7 Page557(2009.11)<\/p>\n\n\n\n

\u5e73\u621022\u5e74\uff082010\u5e74\uff09<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u6771\u91ce \u53f2\u88d5, \u9032\u85e4 \u6b63\u4fe1, \u5317\u6751 \u54f2\u4e5f\uff1aARE-mRNA\u306e\u6838\u5916\u8f38\u9001\u3068\u53e3\u8154\u304c\u3093\u3068\u306e\u95a2\u9023. \u7b2c99\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\uff08\u6771\u4eac\uff092010\u5e744\u6708 \u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u4f1a\u8a8c99\u5dfb1\u53f7 Page308(2010.03)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9\uff1a\u63a5\u5408\u90e8\u578b\u5148\u5929\u6027\u8868\u76ae\u6c34\u75b1\u75c7\u306b\u304a\u3051\u308b\u30a8\u30ca\u30e1\u30eb\u8cea\u5f62\u6210\u4e0d\u5168\u306e\u767a\u75c7\u6a5f\u5e8f\u306e\u89e3\u6790. \u5e73\u621022\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6b6f\u5b66\u4f1a\u8cde\u53d7\u8cde\u8b1b\u6f14\uff09\uff08\u672d\u5e4c\uff092010\u5e745\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c31\u5dfb1\u53f7 Page17-18(2010.06)<\/p>\n\n\n\n

\u576a\u4e95 \u5bff\u5178, \u67cf\u5d0e \u6674\u5f66, \u963f\u90e8 \u8cb4\u6075, \u7b20\u5e2b \u4e45\u7f8e\u5b50, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f, \u4e95\u4e0a \u8fb2\u592b\u7537\uff1a\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u60a3\u8005\u306b\u304a\u3051\u308b\u91cd\u75c7\u53e3\u8154\u7c98\u819c\u708e\u767a\u75c7\u3068\u6804\u990a\u72b6\u614b\u3068\u306e\u95a2\u9023\u6027. \u7b2c48\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u90e8\u4f1a\uff08\u4ed9\u53f0\uff092010\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page26(2011.01)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u660e, \u6749\u6d66 \u5343\u5c0b, \u79e6 \u6d69\u4fe1, \u963f\u90e8 \u8cb4\u6d0b, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u80cc\u90e8\u306e\u6241\u5e73\u82d4\u766c\u304b\u3089\u767a\u751f\u3057\u305f\u3068\u8003\u3048\u3089\u308c\u308b\u6241\u5e73\u4e0a\u76ae\u764c\u306e1\u4f8b\uff0e\u7b2c48\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c36\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u4ed9\u53f0\uff092010\u5e745\u6708<\/p>\n\n\n\n

\u6885\u672c \u7d18\u5b50, \u4e2d\u6751 \u88d5\u4ecb, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aFDG-PET\u304c\u6709\u7528\u3067\u3042\u3063\u305f\u53e3\u84cb\u90e8Marginal zone B-cell lymphoma\u306e1\u4f8b. \u7b2c 36 \u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u4ed9\u53f0\uff092010\u5e745\u6708<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3092\u6765\u3057\u3066\u3044\u305f\u7d05\u677f\u75c7\u69d8\u75c5\u5909\u306e2\u4f8b. \u7b2c36\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u4ed9\u53f0\uff092010\u5e745\u6708<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u4f50\u85e4 \u6df3, \u5bfa\u7530 \u5178\u5b50, \u4f50\u85e4 \u5065\u5f66, \u79e6 \u6d69\u4fe1, \u6749\u6d66 \u5343\u5c0b, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u958b\u53e3\u969c\u5bb3\u306e\u7cbe\u67fb\u4f9d\u983c\u3067\u53d7\u8a3a\u3057\u305f\u7834\u50b7\u98a8\u306e1\u4f8b. \u7b2c48\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c36\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u4ed9\u53f0\uff092010\u5e74 5\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page28(2011.01)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u7af9\u5185 \u5eb7\u4eba, \u5bfa\u7530 \u5178\u5b50, \u5c71\u5d0e \u88d5, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f\uff1a\u91d1\u5c5e\u30a2\u30ec\u30eb\u30ae\u30fc\u60a3\u8005\u306b\u5bfe\u3059\u308b\u5f53\u79d1\u306e\u53d6\u308a\u7d44\u307f. \u7b2c48\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c36\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u4ed9\u53f0\uff092010\u5e745\u6708<\/p>\n\n\n\n

\u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u91ce\u8c37 \u5065\u4e00, \u4f50\u85e4 \u5343\u6674, \u5317\u68ee \u6b63\u543e, \u592a\u5b50 \u82b3\u4eba, \u7b95\u8f2a \u548c\u884c, \u6c34\u8d8a \u5b5d\u5178, \u5317\u5ddd \u5584\u653f\uff1a\u8033\u4e0b\u817a\u5185\u306b\u553e\u6db2\u8caf\u7559\u3092\u7591\u3046\u5927\u304d\u306a\u56a2\u80de\u6027\u75c5\u5909\u3092\u4f34\u3063\u305f\u82e5\u5e74\u578bSjoegren\u75c7\u5019\u7fa4\u306e1\u4f8b. \u7b2c23\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u7dcf\u4f1a\uff08\u677e\u6238\uff092010\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c23\u5dfb2\u53f7 Page374(2010.10)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u6751\u7530 \u7ffc, \u5f8c\u85e4 \u96bc, \u5927\u5185 \u5b66, \u5b88\u5c4b \u4fe1\u543e, \u5317\u5ddd \u5584\u653f\uff1a\u5728\u5b85\u5065\u5eb7\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u83cc\u306e\u4fdd\u83cc\u72b6\u614b\u306b\u95a2\u3059\u308b\u8abf\u67fb. \u7b2c64\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092010\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page85-86(2011.01)<\/p>\n\n\n\n

\u7af9\u5185 \u5eb7\u4eba, \u4f50\u85e4 \u5343\u6674, \u6751\u7530 \u7ffc, \u4f50\u85e4 \u6df3, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u81b5\u764c\u306e\u982d\u84cb\u5185\u8ee2\u79fb\u306b\u3088\u308b\u820c\u4e0b\u795e\u7d4c\u9ebb\u75fa\u3092\u8a8d\u3081\u305f1\u4f8b. \u7b2c64\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092010\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page64(2011.01)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u5f8c\u85e4 \u96bc, \u5927\u5185 \u5b66, \u5b88\u5c4b \u4fe1\u543e, \u5317\u5ddd \u5584\u653f\uff1a\u5728\u5b85\u5065\u5eb7\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b\u5473\u899a\u969c\u5bb3\u3068\u8840\u6e05\u4e2d\u5fae\u91cf\u91d1\u5c5e\u5143\u7d20\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c64\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092010\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page97(2011.01)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u764c\u306b\u304a\u3051\u308b, HuR\u3092\u4ecb\u3057\u305fARE-mRNA\u306e\u6838\u5916\u8f38\u9001\u3068\u5b89\u5b9a\u5316. \u7b2c64\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092010\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page160-161(2011.01)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u6cbb\u7642\u524d\u306e\u75bc\u75db\u306b\u95a2\u9023\u3059\u308b\u56e0\u5b50\u306e\u7814\u7a76(\u7b2c\u56db\u5831)\u3000\u75bc\u75db\u306f\u764c\u306e\u5185\u5411\u6027\u5897\u6b96\u306b\u95a2\u9023\u3057\u3066\u4e88\u5f8c\u3092\u5de6\u53f3\u3059\u308b. \u7b2c64\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092010\u5e746\u6708 \u6284\u9332P145 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb1\u53f7 Page148(2011.01)<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u5317\u7530 \u79c0\u662d, \u698a\u539f \u5178\u5e78, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247, \u95a2\u5802 \u5145\uff1asecond free flap\u306b\u3088\u308b\u984e\u53e3\u8154\u518d\u5efa\u4f8b\u306e\u691c\u8a0e. \u7b2c34\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u6771\u4eac\uff092010\u5e746\u6708 \u982d\u9838\u90e8\u764c36\u5dfb2\u53f7 Page159(2010.05)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u6751\u7530 \u7ffc, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u9ed2\u5d8b \u4f38\u4e00\u90ce, \u5c0f\u91ce\u6728 \u5b8f\u4ef2, \u91ce\u8c37 \u5065\u6cbb, \u6797 \u5229\u5f66, \u53e4\u5ddd \u6d0b\u5fd7, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u53e3\u8154\u764c\u306e\u4e0b\u984e\u5e83\u7bc4\u5207\u9664\u4f8b\u306b\u5bfe\u3059\u308b\u984e\u5824\u5f62\u6210\u8853. \u7b2c34\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u540d\u53e4\u5c4b\uff092010\u5e746\u6708 \u982d\u9838\u90e8\u764c36\u5dfb2\u53f7 Page226(2010.05)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u6751\u7530 \u7ffc, \u4f50\u85e4 \u6df3, \u5c71\u5d0e \u88d5, \u5927\u5185 \u5b66, \u677e\u4e0b \u8cb4\u6075, \u67cf\u5d0e \u6674\u5f66, \u5317\u5ddd \u5584\u653f\uff1a\u30c1\u30fc\u30e0\u3067\u3081\u3056\u3059\u53e3\u8154\u30b1\u30a2 \u5317\u6d77\u9053\u5927\u5b66\u75c5\u9662\u306b\u304a\u3051\u308b\u53e3\u8154\u30b1\u30a2. \u7b2c12\u56de\u65e5\u672c\u533b\u7642\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\u5b66\u4f1a\uff08\u672d\u5e4c\uff092010\u5e746\u6708 \u65e5\u672c\u533b\u7642\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\u5b66\u4f1a\u96d1\u8a8c11\u5dfbSuppl. Page151(2010.06)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u6751\u7530 \u7ffc, \u5317\u5ddd \u5584\u653f\uff1a\u3046\u3064\u75c5\u6027\u969c\u5bb3\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c8\u3067\u3042\u308bPHQ-9\u306e\u53e3\u8154\u5fc3\u8eab\u75c7\u306b\u5bfe\u3059\u308b\u4f7f\u7528\u7d4c\u9a13. \u7b2c25\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\uff08\u5e83\u5cf6\uff092010\u5e747\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c25\u5dfb2\u53f7 Page82(2010.12)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5317\u68ee \u6b63\u543e, \u5c0f\u91ce\u5bfa \u9ebb\u7d00\u5b50, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u65e9\u671f\u306b\u6b6f\u6839\u5185\u90e8\u5438\u53ce\u3092\u751f\u3058\u305f\u4e0a\u984e\u524d\u6b6f\u90e8\u6b6f\u69fd\u9aa8\u9aa8\u6298\u3092\u4f34\u3063\u305f\u6b6f\u7259\u8131\u81fc\u306e1\u4f8b. \u7b2c12\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e83\u5cf6\u5e02\uff092010\u5e747\u6708 \u6284\u9332P45 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b79\u5dfb1\u53f7 Page37-38(2010.06)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c0f\u7b20\u539f \u5229\u884c, \u4f50\u91ce \u548c\u751f, \u5317\u5ddd \u5584\u653f\uff1a\u6210\u9577\u671f\u306esoft diet\u304c\u30a6\u30b5\u30ae\u306e\u54ac\u7b4b\u304a\u3088\u3073\u5185\u30fb\u5916\u5074\u7ffc\u7a81\u7b4b\u306b\u304a\u3088\u307c\u3059\u5f71\u97ff\u306b\u3064\u3044\u3066. \u7b2c23\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092010\u5e747\u6708 \u6284\u9332P78 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c22\u5dfbSuppl. Page78(2010.07)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u5065\u5f66, \u5f8c\u85e4 \u96bc, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5185\u75c5\u5909\u3092\u521d\u767a\u75c7\u72b6\u3068\u3057\u305f\u6c34\u75b1\u6027\u6241\u5e73\u82d4\u766c\u306e1\u4f8b. \u7b2c20\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u30fb\u7b2c21\u56de\u65e5\u672c\u81e8\u5e8a\u53e3\u8154\u75c5\u7406\u5b66\u4f1a\uff08\u5927\u962a\uff092010\u5e747\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5c71\u5d0e \u88d5, \u6751\u7530 \u7ffc, \u963f\u90e8 \u8cb4\u6d0b, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u6241\u5e73\u82d4\u766c\u306b\u5bfe\u30577\u304b\u6708\u9593\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u8edf\u818f\u4f7f\u7528\u3057\u305f\u5f8c\u6241\u5e73\u4e0a\u76ae\u764c\u304c\u767a\u75c7\u3057\u305f\u4e00\u4f8b. \u7b2c20\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092010\u5e747\u6708<\/p>\n\n\n\n

Sato J, Yamazaki Y, Satoh A, Notani K and Kitagawa Y : Pain is a prognostic factor in association with cancer growth pattern and clinical stage in patients with oral squamous cell carcinoma. 20th\u3000Congress of the European Association for Cranio-Maxillo-Facial Surgery (Bruges), 2010.9 Abstract P95<\/p>\n\n\n\n

Abe T, Hata H, Yamazaki Y, Satoh A, Notani K, Tamaki N, Kitagawa Y : Prognostic significance of FDG-PET in patients with oral squamous cell carcinoma. European Association for Cranio-Maxillo-Facial Surgery (Bruges), 2010.9<\/p>\n\n\n\n

Umemoto H, Akiyama M, Yanagi T, Sakai K, Aoyama Y, Oizumi A, Suga Y, Kitagawa Y, Shimizu H : New insight into genotype\/phenotype correlation in ABCA12 mutations in harlequin ichthyosis. 40th annual European Society for Dermatological Research meeting (Helsinki), 2010.9 Journal of Investigative Dermatology 130(S2):79 (2011.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3\uff1a\u53e3\u8154\u8a3a\u65ad\u5185\u79d1\u5b66\u6559\u5ba4\u306e\u53d6\u308a\u7d44\u307f. \u5e73\u621022\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a9\u6708\u4f8b\u4f1a\uff08\u672d\u5e4c\uff092010\u5e749\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c31\u5dfb2\u53f7 Page133-134(2010.12)<\/p>\n\n\n\n

\u77f3\u5ddd \u8aa0\uff1a\u5927\u5b66\u306b\u304a\u3051\u308b\u300c\u53e3\u8154\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u79d1\u300d\u306e\u3042\u308a\u65b9. \u5e73\u621022\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a9\u6708\u4f8b\u4f1a\uff08\u672d\u5e4c\uff092010\u5e749\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c31\u5dfb2\u53f7 Page130-131(2010.12)<\/p>\n\n\n\n

\u798f\u7530 \u6b66\u5fd7, \u5e73\u4e95 \u559c\u5e78, \u524d\u6fa4 \u4ec1\u5fd7, \u65b0\u4fdd \u572d\u4eae, \u77f3\u5c3e \u77e5\u4eae, \u5317\u5ddd \u5584\u653f, \u8229\u6a4b \u8aa0\uff1a\u30e9\u30c3\u30c8\u5ef6\u9ac4\u6700\u5f8c\u91ce\u306b\u304a\u3051\u308b\u30a2\u30df\u30ea\u30f3\u5fdc\u7b54\u6027\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u95a2\u3059\u308b\u96fb\u6c17\u751f\u7406\u5b66\u7684\u89e3\u6790. \u7b2c53\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5c90\u961c\uff092010\u5e749\u6708 Journal of Oral Biosciences52\u5dfbSuppl Page131(2010.09)<\/p>\n\n\n\n

\u5317\u68ee \u6b63\u543e, \u539f\u6a4b \u7dbe\u5b50, \u5c71\u5d0e \u88d5, \u912d \u6f22\u5fe0, \u5317\u5ddd \u5584\u653f\uff1a\u54ac\u5408\u6319\u4e0a\u304c\u54bd\u982d\u671f\u56a5\u4e0b\u904b\u52d5\u306b\u304a\u3088\u307c\u3059\u5f71\u97ff\u306b\u3064\u3044\u3066. \u7b2c16\u56de\u65e5\u672c\u6442\u98df\u56a5\u4e0b\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u65b0\u6f5f\uff092010\u5e749\u6708 \u65e5\u672c\u6442\u98df\u30fb\u56a5\u4e0b\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u5b66\u4f1a\u96d1\u8a8c14\u5dfb3\u53f7 Page577(2010.12)<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u308f\u304c\u56fd\u306b\u304a\u3051\u308bOral Medicine(\u53e3\u8154\u5185\u79d1)\u306e\u73fe\u72b6\u3068\u53e3\u8154\u5916\u79d1 \u5317\u5927\u306b\u304a\u3051\u308bOral Medicine(\u53e3\u8154\u5185\u79d1)\u306e\u73fe\u72b6\u3068\u8ab2\u984c. \u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092010\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c56\u5dfbSuppl. Page26(2010.09)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u6751\u7530 \u7ffc, \u5927\u5185 \u5b66, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306f\u5473\u899a\u7570\u5e38\u306e\u539f\u56e0\u306b\u306a\u308b. \u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092010\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c56\u5dfbSuppl. Page118(2010.09)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u963f\u90e8 \u8cb4\u6d0b, \u5317\u5ddd \u6804\u4e8c, \u5b89\u5f66 \u5584\u88d5\uff1a\u8153\u9aa8\u306b\u3088\u308b\u4e0b\u984e\u518d\u5efa\u3092\u884c\u3063\u305f\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u95a2\u9023\u4e0b\u984e\u9aa8\u9aa8\u9ac4\u708e\u306e1\u4f8b. \u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092010\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c56\u5dfbSuppl. Page307(2010.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5c71\u5d0e \u88d5, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u79e6 \u6d69\u4fe1, \u5e73\u5ddd \u76f4, \u8db3\u5229 \u96c4\u4e00, \u912d \u6f22\u5fe0, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u5927\u75c5\u9662\u6b6f\u79d1\u8a3a\u7642\u30bb\u30f3\u30bf\u30fc\u306b\u304a\u3051\u308bBP\u88fd\u5264\u4f7f\u7528\u8005\u306e\u53e3\u8154\u5916\u79d1\u51e6\u7f6e\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u7684\u691c\u8a0e\uff0e\u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092010\u5e7410\u6708<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7\uff1a\u30a2\u30c7\u30ce\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u3088\u308bRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30afHuR\u306e\u5236\u5fa1. \u5e73\u621022\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092010\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c31\u5dfb2\u53f7 Page137(2010.12)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u5b89\u7530 \u5143\u662d, \u5317\u6751 \u54f2\u4e5f, \u77f3\u5ddd \u8aa0, \u5317\u5ddd \u5584\u653f, \u9032\u85e4 \u6b63\u4fe1, \u6771\u91ce \u53f2\u88d5\uff1a\u30a2\u30c7\u30ce\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306f\u5bbf\u4e3b\u7d30\u80de\u306eStress granules\u3068P-Bodies\u306b\u7279\u7570\u7684\u306a\u5909\u5316\u3092\u3082\u305f\u3089\u3059. \u7b2c83\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a\u30fb\u7b2c33\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u5408\u540c\u5927\u4f1a\uff08\u795e\u6238\uff092010\u5e7412\u6708 \u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a\u30fb\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\u5408\u540c\u5927\u4f1a\u8b1b\u6f14\u8981\u65e8\u96c683\u56de\u30fb33\u56de Page2P-0664(2010.12)<\/p>\n\n\n\n

\u6885\u672c \u7d18\u5b50, \u79cb\u5c71 \u771f\u5fd7, \u67f3 \u8f1d\u5e0c, \u5742\u4e95 \u9999\u7e54, \u9752\u5c71 \u88d5\u7f8e, \u5927\u6cc9 \u4e9c\u7f8e, \u9808\u8cc0 \u5eb7, \u5317\u5ddd \u5584\u653f, \u6e05\u6c34 \u5b8f\uff1aTwo independent cases with harlequin ichthyosis give us a clue to clarify genotype\/phenotype correlation in ABCA12 mutations.\u3000\u7b2c35\u56de\u65e5\u672c\u7814\u7a76\u76ae\u819a\u79d1\u5b66\u4f1a\uff08\u548c\u6b4c\u5c71\uff092010\u5e7412\u6708<\/p>\n\n\n\n

\u5e73\u621023\u5e74\uff082011\u5e74\uff09<\/p>\n\n\n\n

Sato J, Yamazaki Y, Satoh A, Notani K, Kitagawa Y : Pain can predict poor prognosis in patients with oral SCC. 65th Annual Meeting The American Academy of Oral Medicine. (Puerto Rico), 2011.4 Abstract P19<\/p>\n\n\n\n

Hata H, Yamazaki Y, Sato J, Takeuchi Y, Murata T, Oouchi M, Kitagawa Y : A clinical study of patients with psychosomatic taste disorders. 65th Annual Meeting of the American Academy of Oral Medicine (Puerto Rico), 2011.4<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u67f3\u5ddd \u5f69, \u9032\u85e4 \u6b63\u4fe1\uff1aARE-mRNA\u306e\u5b89\u5b9a\u5316\u306f\u7d30\u80de\u304c\u3093\u5316\u3092\u8a98\u5c0e\u3059\u308b. \u7b2c100\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\uff08\u6a2a\u6d5c\uff092011\u5e744\u6708 \u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u4f1a\u8a8c100\u5dfb1\u53f7 Page342(2011.03)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u79e6 \u6d69\u4fe1, \u963f\u90e8 \u8cb4\u6d0b, \u5e73\u5ddd \u76f4, \u8db3\u5229 \u96c4\u4e00, \u912d \u6f22\u5fe0, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1a\u7d4c\u53e3\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u88fd\u5264\u670d\u7528\u60a3\u8005\u306e\u629c\u6b6f\u5f8c\u6cbb\u7652\u7d4c\u904e\u306b\u95a2\u3059\u308b\u5f8c\u308d\u5411\u304d\u8abf\u67fb\uff0e\u7b2c3\u56de\u5317\u6d77\u9053\u53e3\u8154\u5185\u79d1\u7814\u7a76\u4f1a 2011\u5e744\u6708<\/p>\n\n\n\n

\u798f\u7530 \u6b66\u5fd7, \u5317\u5ddd \u5584\u653f, \u8229\u6a4b \u8aa0\uff1a\u30e9\u30c3\u30c8\u5ef6\u9ac4\u6700\u5f8c\u91ce\u306b\u304a\u3051\u308b\u30a2\u30df\u30ea\u30f3\u306b\u3088\u308b\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u306e\u4fee\u98fe. \u7b2c65\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092011\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page176(2012.01)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u79e6 \u6d69\u4fe1, \u963f\u90e8 \u8cb4\u6d0b, \u5e73\u5ddd \u76f4, \u8db3\u5229 \u96c4\u4e00, \u912d \u6f22\u5fe0, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u5927\u75c5\u9662\u6b6f\u79d1\u8a3a\u7642\u30bb\u30f3\u30bf\u30fc\u306b\u304a\u3051\u308b\u7d4c\u53e3BP\u88fd\u5264\u4f7f\u7528\u8005\u306e\u629c\u6b6f\u8853\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u7684\u691c\u8a0e\uff0e\u7b2c65\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092011\u5e744\u6708<\/p>\n\n\n\n

\u6c34\u8c37 \u7be4\u53f2, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u5065\u5f66, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u7ba1\u306e\u62e1\u5927\u3092\u4f34\u3063\u305f\u3001\u4e0b\u6b6f\u69fd\u795e\u7d4c\u7531\u6765\u795e\u7d4c\u5468\u819c\u816b\u306e1\u4f8b. \u7b2c65\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092011\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page210(2012.01)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u6cbb\u7642\u524d\u306e\u75db\u307f\u306f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u4e88\u5f8c\u4e0d\u826f\u3092\u4e88\u6e2c\u3059\u308b\u56e0\u5b50\u3068\u306a\u308a\u3048\u308b\u304b? \u7b2c65\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092011\u5e744\u6708 \u6284\u9332P252 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page102(2012.01)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c\uff1a\u9577\u671f\u306b\u308f\u305f\u308a\u5897\u5927\u30fb\u7e2e\u5c0f\u3092\u7e70\u308a\u8fd4\u3057\u305f\u53e3\u5e95\u90e8\u30ea\u30f3\u30d1\u7ba1\u816b\u306e\uff11\u4f8b. \u7b2c37\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u65b0\u6f5f\uff092011\u5e745\u6708<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u52a0\u5cf6 \u88d5\u57fa, \u5317\u5ddd \u5584\u653f\uff1a\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u304b\u3089\u60f9\u8d77\u3055\u308c\u305f\u3068\u601d\u308f\u308c\u308b\u53e3\u8154\u7c98\u819c\u6f70\u760d\u306e\uff11\u4f8b. \u7b2c37\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u65b0\u6f5f\uff092011\u5e745\u6708<\/p>\n\n\n\n

\u6c34\u8c37 \u7be4\u53f2, \u5c71\u5d0e \u88d5, \u5f8c\u85e4 \u6e96, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u5927\u75c5\u9662\u53e3\u8154\u5185\u79d1\u306b\u304a\u3051\u308b\u5473\u899a\u7570\u5e38\u75c7\u4f8b\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c49\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u90e8\u4f1a\u30fb\u7b2c37\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u65b0\u6f5f\uff092011\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c60\u5dfb4\u53f7 Page358(2011.09)<\/p>\n\n\n\n

\u52a0\u5cf6 \u88d5\u57fa, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a BRONJ\u306b\u304a\u3051\u308b\u9ad8\u5727\u9178\u7d20\u7642\u6cd5\u306e\u8a55\u4fa1\u306bFDG-PET\u304c\u6709\u7528\u3067\u3042\u3063\u305f\u4e00\u4f8b. \u7b2c37\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u65b0\u6f5f\uff092011\u5e745\u6708<\/p>\n\n\n\n

\u5927\u4e45\u4fdd \u76f4\u767b\uff1a\u6b6f\u6839\u819c\u7531\u6765\u5e79\u7d30\u80de\u306b\u3088\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u30de\u30fc\u30ab\u30fc\u967d\u6027\u8840\u7ba1\u69cb\u9020\u306e\u69cb\u7bc9. \u5e73\u621023\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6b6f\u5b66\u4f1a\u8cde\u53d7\u8cde\u8b1b\u6f14\uff09\uff08\u672d\u5e4c\uff092011\u5e745\u6708<\/p>\n\n\n\n

\u6751\u4e95 \u77e5\u4f73, \u72ac\u4f0f \u6b63\u5e78, \u91d1 \u6c38\u7537, \u79e6 \u6d69\u4fe1, \u53e4\u5ddd \u9ad8\u5b50, \u5c0f\u6cc9 \u6e80, \u4f50\u8cc0 \u6052\u592b, \u5317\u5ddd \u5584\u653f\uff1a\u4f4e\u9178\u7d20\u5fdc\u7b54\u6027\u30ec\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\u5b89\u5b9a\u767a\u73fe\u30d2\u30c8\u30b0\u30ea\u30aa\u30fc\u30de\u7d30\u80de\u682a\u306e\u6a39\u7acb. \u7b2c24\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092011\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c24\u5dfb3\u53f7 Page471-472(2011.10)<\/p>\n\n\n\n

Kuroshima T, Kitamura T, Yanagawa-Matsuda A, Shindoh M and Higashino F : Modulation of P bodies and stress granules in adenovirus infected cells. RNA 2011 (Sixteenth Annual Meeting of the RNA Society) (Kyoto), 2011.6<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Abe T, Hattori N, Takei T, Shiga T, Shindoh M, Tamaki N : FMISO PET reflects the pathological characteristics of oral squamous cell carcinoma. 2011 SNMI annual meeting (San Antonio), 2011.6 Abstract P418<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u6751\u7530 \u7ffc, \u6751\u4e95 \u77e5\u4f73, \u4eca\u5f85 \u8ce2\u6cbb, \u672c\u9593 \u660e\u5b8f, \u5317\u5ddd \u5584\u653f\uff1a\u982d\u9838\u90e8\u764c\u60a3\u8005\u3092\u652f\u3048\u308b\u30c1\u30fc\u30e0\u533b\u7642 \u5927\u5b66\u75c5\u9662\u3067\u306e\u982d\u9838\u90e8\u304c\u3093\u6cbb\u7642\u306b\u304a\u3051\u308b\u53e3\u8154\u30b1\u30a2\u306e\u53d6\u308a\u7d44\u307f\u306b\u3064\u3044\u3066. \u7b2c35\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u540d\u53e4\u5c4b\uff092011\u5e746\u6708 \u982d\u9838\u90e8\u764c37\u5dfb2\u53f7 Page181(2011.05)<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u79e6 \u6d69\u4fe1, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u518d\u767a\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c35\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u540d\u53e4\u5c4b\uff092011\u5e746\u6708 \u982d\u9838\u90e8\u764c37\u5dfb2\u53f7 Page238(2011.05)<\/p>\n\n\n\n

Sato J, Satoh C, Kitagawa Y : A case of tetanus appropriately managed by early diagnosis in oral medicine clinic. Joint Meeting of 2nd Asian Academic Congress for Temporomandibular Joint and 24th Annual Meeting of Japanese Society for Temporomandibular Joint (Hiroshima), 2011.7 Abstract P159<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u6751\u4e95 \u77e5\u4f73, \u6751\u7530 \u7ffc, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u5185\u306b\u306f\u4f55\u3082\u306a\u3044\u306e\u306b\u5473\u899a\u7570\u5e38\u3092\u8a34\u3048\u308b\u81ea\u767a\u6027\u7570\u5e38\u5473\u899a\u306b\u304a\u3051\u308b\u5fc3\u7406\u7684\u56e0\u5b50\u306e\u691c\u8a0e. \u7b2c26\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092011\u5e747\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1-2\u53f7 Page73(2012.12)<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u4f50\u85e4 \u5065\u5f66, \u5bae\u8170 \u660c\u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u6551\u6025\u79d1\u7d39\u4ecb\u60a3\u8005\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c13\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5bae\u5d0e\uff092011\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b710\u5dfb1\u53f7 Page35-36(2011.06)<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u4f50\u85e4 \u660e, \u4f50\u85e4 \u5065\u5f66, \u9ed2\u5d8b \u96c4\u5fd7, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3044\u3066\u4fdd\u5b58\u7642\u6cd5\u3092\u65bd\u884c\u3057\u305f\u4e0b\u984e\u9aa8\u9aa8\u6298\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c13\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5bae\u5d0e\uff092011\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b710\u5dfb1\u53f7 Page35(2011.06)<\/p>\n\n\n\n

Kuroshima T, Yasuda M, Kitamura T, Yanagawa-Matsuda A, Shindoh M and Higashino F : Stabilization of AU-rich element containing mRNA mediated by adenovirus gene product contributes to cell transformation. International Union of Microbiological Societies 2011 Congress (Sapporo), 2011.9<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306e\u3044\u307e(Oral candidiasis update) \u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3068\u5473\u899a\u7570\u5e38. \u7b2c21\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\uff08\u9e7f\u5150\u5cf6\uff092011\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c17\u5dfb2\u53f7 Page64(2011.12)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u6c34\u8c37 \u7be4\u53f2, \u5317\u5ddd \u5584\u653f\uff1a\u8840\u6e05\u4e9c\u925b\u5024\u306f\u5473\u899a\u7570\u5e38\u60a3\u8005\u306b\u304a\u3044\u3066\u91cd\u8981\u304b. \u7b2c21\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\uff08\u9e7f\u5150\u5cf6\uff092011\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c17\u5dfb2\u53f7 Page68(2011.12)<\/p>\n\n\n\n

\u6749\u5c71 \u6b63\u535a, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u5f8c\u85e4 \u96bc, \u5927\u5185 \u5b66, \u5317\u5ddd \u5584\u653f\uff1a\u52a0\u9f62\u306b\u4f34\u3046\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u83cc\u53e2\u306e\u5909\u5316\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c21\u56de\u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u7dcf\u4f1a\uff08\u9e7f\u5150\u5cf6\uff092011\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u7c98\u819c\u5b66\u4f1a\u96d1\u8a8c17\u5dfb2\u53f7 Page70(2011.12)<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u984e\u9854\u9762\u9818\u57df\u306b\u304a\u3051\u308bPET\u8a3a\u65ad\u306e\u6709\u7528\u6027\u3068\u8ab2\u984c. \u7b2c51\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u3064\u304f\u3070\uff092011\u5e7410\u6708 \u6838\u533b\u5b6648\u5dfb3\u53f7 Page np1(2011.09)<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u6751\u4e95 \u77e5\u4f73, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f, \u5fd7\u8cc0 \u54f2, \u7af9\u4e95 \u4fca\u6a39\uff1a11C-Methionine PET\u3092\u7528\u3044\u305f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u8a55\u4fa1\u30fb\u691c\u8a0e. \u7b2c51\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u3064\u304f\u3070\uff092011\u5e7410\u6708 \u6838\u533b\u5b6648\u5dfb3\u53f7 Page S226(2011.09)<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u6df3, \u6749\u6d66 \u5343\u5c0b, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u5c0f\u91ce \u8ca2\u4f38, \u6238\u585a \u9756\u5247\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306b\u304a\u3051\u308b11C-Methionine PET\u306e\u6709\u7528\u6027. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page321(2011.09)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u79e6 \u6d69\u4fe1, \u6c34\u8c37 \u7be4\u53f2, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306b\u5bfe\u3059\u308b\u6297\u771f\u83cc\u7642\u6cd5\u306b\u3088\u308a\u53e3\u8154\u4e7e\u71e5\u75c7\u72b6\u306f\u6539\u5584\u3059\u308b. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5927\u5742\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page91(2011.09)<\/p>\n\n\n\n

\u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u8db3\u5229 \u96c4\u4e00, \u5927\u5ee3 \u6d0b\u4e00, \u677e\u6ca2 \u7950\u4ecb, \u5c0f\u91ce \u8ca2\u4f38, \u6238\u585a \u9756\u5247, \u7b95\u8f2a \u548c\u884c, \u6edd\u6ce2 \u4fee\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u65bd\u8a2d\u306b\u304a\u3051\u308b\u3073\u307e\u3093\u6027\u786c\u5316\u6027\u4e0b\u984e\u9aa8\u9aa8\u9ac4\u708e\u306e\u81e8\u5e8a\u7684\u691c\u8a0e\u3000\u81e8\u5e8a\u75c5\u614b\u306b\u3064\u3044\u3066. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page137(2011.09)<\/p>\n\n\n\n

\u8db3\u5229 \u96c4\u4e00, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f, \u677e\u6ca2 \u7950\u4ecb, \u5927\u5ee3 \u6d0b\u4e00, \u5c0f\u91ce \u8ca2\u4f38, \u7b95\u8f2a \u548c\u884c, \u6edd\u6ce2 \u4fee\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u6238\u585a \u9756\u5247\uff1a\u5f53\u65bd\u8a2d\u306b\u304a\u3051\u308b\u3073\u307e\u3093\u6027\u786c\u5316\u6027\u4e0b\u984e\u9aa8\u9aa8\u9ac4\u708e\u306e\u81e8\u5e8a\u7684\u691c\u8a0e\u3000\u6cbb\u7642\u52b9\u679c\u306b\u3064\u3044\u3066. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page137(2011.09)<\/p>\n\n\n\n

\u6c34\u8c37 \u7be4\u53f2, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u5473\u899a\u969c\u5bb3\u60a3\u8005\u306b\u304a\u3051\u308b\u8840\u6e05\u4e9c\u925b\u5024\u3068\u6ffe\u7d19\u30c7\u30a3\u30b9\u30af\u6cd5\u306b\u3088\u308b\u5473\u899a\u6a5f\u80fd\u691c\u67fb\u3068\u306e\u95a2\u9023. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page175(2011.09)<\/p>\n\n\n\n

\u91d1\u5b50 \u771f\u68a8, \u912d \u6f22\u5fe0, \u6ff1\u7530 \u6d69\u7f8e, \u5c0f\u91ce \u8ca2\u4f38, \u5c71\u5d0e \u88d5, \u5317\u68ee \u6b63\u543e, \u5317\u5ddd \u5584\u653f, \u6238\u585a \u9756\u5247\uff1a\u80c3\u308d\u3046\u3092\u9020\u8a2d\u3057\u305f\u53e3\u8154\u304c\u3093\u60a3\u8005\u306e\u8853\u5f8c\u306e\u7d4c\u904e\u3068\u6804\u990a\u72b6\u614b\u306b\u3064\u3044\u3066. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page195(2011.09)<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u79e6 \u6d69\u4fe1, \u963f\u90e8 \u8cb4\u6d0b, \u4f50\u85e4 \u5065\u5f66, \u6749\u6d66 \u5343\u5c0b, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u65b0\u305f\u306a\u53e3\u8154\u5185\u76ae\u819a\u79fb\u690d\u8853\u306e\u8a66\u307f. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page215(2011.09)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u963f\u90e8 \u8cb4\u6d0b, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u5343\u6674, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u57cb\u5165\u3092\u5951\u6a5f\u3068\u3057\u305f\u6162\u6027\u75bc\u75db\u304b\u30898\u5e74\u5f8c\u306bSAPHO\u75c7\u5019\u7fa4\u3068\u8a3a\u65ad\u3055\u308c\u305f1\u4f8b. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page287(2011.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u6751\u4e95 \u77e5\u4f73, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u553e\u6db2\u4e2dIL-6\u6fc3\u5ea6\u306f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u539f\u767a\u90e8\u518d\u767a\u30fb\u9838\u90e8\u5f8c\u767a\u8ee2\u79fb\u306b\u95a2\u9023\u3059\u308b. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u6284\u9332P304 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page304(2011.09)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c\uff1a\u5480\u56bc\u969c\u5bb3\u3092\u5951\u6a5f\u306b\u767a\u898b\u3055\u308c\u305f\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u306e1\u4f8b. \u7b2c56\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092011\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c57\u5dfbSuppl. Page157(2011.09)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u77f3\u5ddd \u4fee\u5e73, \u6a0b\u7530 \u6cf0\u6d69, \u79cb\u5c71 \u5e83\u8f14, \u9593\u77f3 \u5948\u6e56, \u8fd1\u85e4 \u7f8e\u5f25\u5b50, \u5ddd\u672c \u6cf0\u8f14, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u8ee2\u79fb\u80fd\u306e\u7570\u306a\u308b\u816b\u760d\u304b\u3089\u5206\u96e2\u3055\u308c\u305f\u816b\u760d\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u6bd4\u8f03\u89e3\u6790(Comparative characterization of tumor endothelial cells isolated from highly and low metastatic tumors). \u7b2c70\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u540d\u53e4\u5c4b\uff092011\u5e7410\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b70\u56de Page430(2011.09)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u5317\u6751 \u54f2\u4e5f, \u67f3\u5ddd\uff0d\u677e\u7530 \u5f69, \u9032\u85e4 \u6b63\u4fe1, \u6771\u91ce \u53f2\u88d5\uff1app32\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u3088\u308bRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30afHuR\u306e\u5236\u5fa1. \u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\uff08\u6a2a\u6d5c\uff092011\u5e7412\u6708<\/p>\n\n\n\n

\u6885\u672c \u7d18\u5b50, \u79cb\u5c71 \u771f\u5fd7, \u571f\u9580 \u5353\u6587, \u4e43\u6751 \u4fca\u53f2, \u65b0\u718a \u609f, \u4f0a\u85e4 \u572d, \u6d45\u9999 \u5353\u54c9, \u6fa4\u6751 \u5927\u8f14, Jouni Uitto, \u5b87\u5c3e \u57fa\u5f18, \u5317\u5ddd \u5584\u653f, \u6e05\u6c34 \u5b8f\uff1aType VII collagen deficiency causes defective tooth enamel formation due to poor differentiation of ameloblasts. \u7b2c36\u56de\u65e5\u672c\u7814\u7a76\u76ae\u819a\u79d1\u5b66\u4f1a\uff08\u4eac\u90fd\uff092011\u5e7412\u6708<\/p>\n\n\n\n

\u5e73\u621024\u5e74\uff082012\u5e74\uff09<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u4f50\u85e4 \u660e, \u9ed2\u5d8b \u96c4\u5fd7, \u6749\u6d66 \u5343\u5c0b, \u963f\u90e8 \u8cb4\u6d0b, \u79e6 \u6d69\u4fe1, \u91ce\u8c37 \u5065\u4e00, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u982c\u7c98\u819c\u6241\u5e73\u4e0a\u76ae\u304c\u3093\u3068\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u7d50\u6838\u306e\u5408\u4f75\u3057\u305f1\u4f8b. \u7b2c30\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u57fc\u7389\uff092012\u5e741\u6708<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u5065\u5f66, \u4f50\u85e4 \u660e, \u6749\u6d66 \u5343\u5c0b, \u963f\u90e8 \u8cb4\u6d0b, \u79e6 \u6d69\u4fe1, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\uff08MTX\uff09\u4e2d\u6b62\u5f8c\u306b\u518d\u71c3\u304c\u8a8d\u3081\u3089\u308c\u305f\u9838\u90e8MTX\u95a2\u9023\u30ea\u30f3\u30d1\u816b\u306e1\u4f8b. \u7b2c30\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\uff08\u57fc\u7389\uff092012\u5e741\u6708<\/p>\n\n\n\n

Oouchi M, Segawa T, Hasebe A, Shibata K : Relationships between oral candidiasis and expression and functions of TLRs or NK activity. \u7b2c85\u56de\u65e5\u672c\u7d30\u83cc\u5b66\u4f1a\u7dcf\u4f1a\uff08\u9577\u5d0e\uff092012\u5e743\u6708 \u65e5\u672c\u7d30\u83cc\u5b66\u96d1\u8a8c67\u5dfb1\u53f7 Page154(2012.02)<\/p>\n\n\n\n

\u67f3\u5ddd \u5f69[\u677e\u7530], \u9ed2\u5d8b \u96c4\u5fd7, \u5317\u6751 \u54f2\u4e5f, \u6771\u91ce \u53f2\u88d5, \u9032\u85e4 \u6b63\u4fe1\uff1a\u30a2\u30c7\u30ce\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u304c\u3082\u305f\u3089\u3059\u5bbf\u4e3b\u7d30\u80deP-body\u306e\u5909\u5316. \u7b2c101\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\uff08\u6771\u4eac\uff092012\u5e744\u6708<\/p>\n\n\n\n

\u53e4\u6a4b \u4e00\u61b2, \u8d64\u5742 \u53f8, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u30ca\u30ce\u30a2\u30d1\u30bf\u30a4\u30c8\u8907\u5408\u5316\u6750\u6599\u4e0a\u3067\u306e\u7d30\u80de\u6319\u52d5. \u7b2c59\u56de\u65e5\u672c\u6b6f\u79d1\u7406\u5de5\u5b66\u4f1a\u5b66\u8853\u8b1b\u6f14\u4f1a\uff08\u5fb3\u5cf6\uff092012\u5e744\u6708 \u65e5\u672c\u6b6f\u79d1\u7406\u5de5\u5b66\u4f1a\u8a8c31\u5dfb2\u53f7 Page136(2012.03)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u5742\u7530 \u5065\u4e00\u90ce, \u5927\u5185 \u5b66, \u5f8c\u85e4 \u96bc, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u3067\u5206\u96e2\u3055\u308c\u305fCandida glabrata\u306e\u85ac\u5264\u611f\u53d7\u6027\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u7dcf\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page52(2013.01)<\/p>\n\n\n\n

\u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u9ed2\u5d8b \u96c4\u5fd7, \u6751\u4e95 \u77e5\u4f73, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u6ce8\u5c04\u7528\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u88fd\u5264\u6295\u4e0e\u524d\u306b\u304a\u3051\u308b\u6b6f\u79d1\u53d7\u8a3a\u306e\u91cd\u8981\u6027. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page51(2013.01)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u6c34\u8c37 \u7be4\u53f2, \u5317\u5ddd \u5584\u653f\uff1a\u3059\u3079\u3066\u306e\u5473\u899a\u969c\u5bb3\u60a3\u8005\u306b\u5bfe\u3057\u4e9c\u925b\u88fd\u5264\u306e\u88dc\u5145\u306f\u6709\u52b9\u304b? \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page55(2013.01)<\/p>\n\n\n\n

\u798f\u7530 \u6b66\u5fd7, \u8229\u6a4b \u8aa0, \u5317\u5ddd \u5584\u653f\uff1a\u524d\u30b7\u30ca\u30d7\u30b9\u90e8\u30a2\u30df\u30ea\u30f3\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u305f\u6700\u5f8c\u91ce\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u6d3b\u52d5\u5236\u5fa1. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page78-79(2013.01)<\/p>\n\n\n\n

\u6885\u672c \u7d18\u5b50, \u6d45\u9999 \u5353\u54c9, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u52a3\u6027\u6804\u990a\u969c\u5bb3\u578b\u8868\u76ae\u6c34\u75b1\u75c7\u306b\u304a\u3051\u308b\u30a8\u30ca\u30e1\u30eb\u8cea\u5f62\u6210\u969c\u5bb3\u767a\u75c7\u6a5f\u5e8f\u306e\u89e3\u6790. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page82(2013.01)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u963f\u90e8 \u8cb4\u6d0b, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aFMISO PET\u306f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u306e\u6709\u7121\u3092\u53cd\u6620\u3059\u308b. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u6284\u9332P207 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page136(2013.01)<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u6751\u4e95 \u77e5\u4f73, \u963f\u90e8 \u8cb4\u6d0b, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1aFDG-PET\/CT\u3092\u7528\u3044\u305f\u53e3\u8154\u764c\u8853\u524d\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u691c\u51fa\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page136(2013.01)<\/p>\n\n\n\n

\u963f\u90e8 \u572d\u543e, \u698a\u539f \u5178\u5e78, \u9234\u6728 \u90a6\u660e, \u5317\u5ddd \u5584\u653f\uff1aRAW264.7\u7d30\u80de\u3092\u7528\u3044\u305f\u7834\u9aa8\u7d30\u80de\u5206\u5316\u8a98\u5c0e\u7cfb\u306b\u5bfe\u3059\u308b\u5404\u7a2e\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u88fd\u5264\u306e\u5f71\u97ff. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb1\u53f7 Page160(2013.01)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u677e\u7530 \u5f69, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aARE-mRNA\u3092\u5b89\u5b9a\u5316\u3055\u305b\u308b\u3053\u3068\u306f\u7d30\u80de\u306e\u304c\u3093\u5316\u306b\u5bc4\u4e0e\u3059\u308b. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page105(2012.01)<\/p>\n\n\n\n

\u5317\u68ee \u6b63\u543e, \u912d \u6f22\u5fe0, \u539f\u6a4b \u7dbe\u5b50, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u54ac\u5408\u6319\u4e0a\u526f\u5b50\u3092\u7528\u3044\u305f\u54ac\u5408\u6319\u4e0a\u304c\u54bd\u982d\u671f\u56a5\u4e0b\u904b\u52d5\u306b\u53ca\u307c\u3059\u5f71\u97ff. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page114(2012.01)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u79e6 \u6d69\u4fe1, \u5e73\u5ddd \u76f4, \u8db3\u5229 \u96c4\u4e00, \u912d \u6f22\u5fe0, \u6238\u585a \u9756\u5247, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u5927\u75c5\u9662\u6b6f\u79d1\u8a3a\u7642\u30bb\u30f3\u30bf\u30fc\u306b\u304a\u3051\u308b\u7d4c\u53e3BP\u88fd\u5264\u4f7f\u7528\u8005\u306e\u629c\u6b6f\u8853\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page130(2012.01)<\/p>\n\n\n\n

\u6c34\u8c37 \u7be4\u53f2, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u5065\u5f66, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u7ba1\u306e\u62e1\u5927\u3092\u4f34\u3063\u305f\u3001\u4e0b\u6b6f\u69fd\u795e\u7d4c\u7531\u6765\u795e\u7d4c\u5468\u819c\u816b\u306e1\u4f8b. \u7b2c66\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5e83\u5cf6\uff092012\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c61\u5dfb1\u53f7 Page210(2012.01)<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Abe T, Kitamura T, Hattori N, Shiga T, Shindoh M, Tamaki N : FMISO PET reflects the pathological findings with cervical lymph node metastasis in oral squamous cell carcinoma. 2012 SNMI annual meeting (Miami Beach), 2012.6 Abstract P197<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Abe T, Kitamura T, Hattori N, Shiga T, Shindoh M, Tamaki N : FMISO PET correlates with the expression of HIF-1\u03b1 in oral squamous cell carcinoma. 2012 SNMI annual meeting (Miami Beach), 2012.6 Abstract P196<\/p>\n\n\n\n

Miyakoshi M, Murai C, Abe T, Hata H, Sato A, Yamazaki Y, Yoshimasa K, Shiga T, Tamaki N : Value and limitation of preoperative lymph node staging using FDG PET\/CT in patients with oral cancer: Comparison with histological findings. 2012 SNM annual Meeting (Miami Beach), 2012.6<\/p>\n\n\n\n

Hata H, Yamazaki Y, Murata T, Yoshikawa K, Uesaka K, Ota Y, Kitagawa Y : A case of dysgeusia caused by zinc deficiency after Pancreaticoduodenectomy. MASCC Annual meeting (New York), 2012.6<\/p>\n\n\n\n

\u91d1\u5c71 \u7d14\u4e00, \u963f\u90e8 \u8cb4\u6d0b, \u4f50\u85e4 \u660e, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u8853\u524d\u306b\u884c\u3063\u305fPET-CT\u691c\u67fb\u3067\u8179\u90e8\u5927\u52d5\u8108\u7624\u3092\u767a\u898b\u3067\u304d\u305f1\u4f8b. \u7b2c50\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c38\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092012\u5e746\u6708<\/p>\n\n\n\n

\u6c34\u8c37 \u7be4\u53f2, \u4f50\u85e4 \u6df3, \u5742\u7530 \u5065\u4e00\u90ce, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30d1\u30c3\u30c1\u30c6\u30b9\u30c8\u304c\u6709\u52b9\u3067\u3042\u3063\u305f\u6b6f\u79d1\u5408\u7740\u30bb\u30e1\u30f3\u30c8\u30a2\u30ec\u30eb\u30ae\u30fc\u304c\u7591\u308f\u308c\u305f1\u4f8b. \u7b2c38\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092012\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u79d1\u5b66\u4f1a\u96d1\u8a8cVol.59 P56<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053\u304c\u3093\u30bb\u30f3\u30bf\u30fc\u6b6f\u79d1\u65b0\u898f\u958b\u8a2d\u306b\u5411\u3051\u3066\u306e\u53d6\u308a\u7d44\u307f. \u7b2c38\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\u5e02\uff092012\u5e746\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u660e, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u5916\u79d1\u7642\u6cd5\u3092\u884c\u3063\u305f\u653e\u5c04\u7dda\u6027\u984e\u9aa8\u9aa8\u9ac4\u708e\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c36\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5cf6\u6839\uff092012\u5e746\u6708 \u982d\u9838\u90e8\u764c38\u5dfb2\u53f7 Page154(2012.05)<\/p>\n\n\n\n

\u6c38\u4e95 \u5eb7\u4e00, \u8349\u6df1 \u516c\u79c0, \u4e2d\u5cf6 \u5b5d, \u671d\u5009 \u5f18\u90c1, \u98ef\u7530 \u5584\u5e78, \u798f\u5bb6 \u667a\u4ec1, \u9b3c\u585a \u54f2\u90ce, \u4e2d\u5ddd \u96c5\u88d5, \u4e95\u4e0a \u5553\u592a, \u4e94\u6765 \u514b\u4e5f, \u5c71\u672c \u88d5\u4ecb, \u9577\u8c37\u5ddd \u6676\u5b50, \u5409\u5ddd \u548c\u4eba, \u767e\u5408\u8349 \u5065\u572d\u5fd7, \u5927\u7530 \u6d0b\u4e8c\u90ce\uff1a\u591a\u5f69\u306a\u7d44\u7e54\u50cf\u3092\u5448\u3057\u8a3a\u65ad\u306b\u82e6\u616e\u3057\u305f\u820c\u4e0b\u817a\u764c\u306e\uff11\u624b\u8853\u4f8b. \u7b2c36\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5cf6\u6839\uff092012\u5e746\u6708 \u982d\u9838\u90e8\u764c \u7b2c38\u5dfb\u30fb\u7b2c2\u53f7 \u7dcf\u4f1a\u53f7Page267 (2012.05)<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u767e\u5408\u8349 \u5065\u572d\u5fd7, \u6c38\u4e95 \u5eb7\u4e00, \u7247\u5ca1 \u667a\u5b50, \u53e4\u5ddd \u5eb7\u5e73, \u5927\u7530 \u6d0b\u4e8c\u90ce, \u4e0a\u689d \u670b\u4e4b, \u98ef\u7530 \u5584\u5e78, \u6dfa\u91ce \u7406\u6075, \u798f\u5bb6 \u667a\u4ec1, \u9b3c\u585a \u54f2\u90ce\uff1a\u982d\u9838\u90e8\u304c\u3093\u60a3\u8005\u6cbb\u7642\u6642\u306e\u53e3\u8154\u5185\u72b6\u6cc1\u3068\u6b6f\u79d1\u51e6\u7f6e\u306b\u95a2\u3059\u308b\u5b9f\u614b\u8abf\u67fb\u3000\u75c5\u9662\u3068\u5730\u57df\u6b6f\u79d1\u533b\u7642\u6a5f\u95a2\u3068\u306e\u9023\u643a\u306e\u53ef\u80fd\u6027. \u7b2c36\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5cf6\u6839\uff092012\u5e746\u6708 \u6284\u9332P256 \u982d\u9838\u90e8\u764c38\u5dfb2\u53f7 Page256(2012.05)<\/p>\n\n\n\n

\u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u9ad8\u9f62\u8005\u8853\u524d\u691c\u67fb\u306b\u304a\u3051\u308b\u5fc3\u30a8\u30b3\u30fc\u306e\u7d50\u679c\u306b\u3064\u3044\u3066. \u7b2c27\u56de\u5317\u6d77\u9053\u81e8\u5e8a\u6b6f\u79d1\u9ebb\u9154\u5b66\u4f1a\uff08\u51fd\u9928\uff092012\u5e746\u6708<\/p>\n\n\n\n

\u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u9ad8\u9f62\u8005\u8853\u524d\u691c\u67fb\u306b\u304a\u3051\u308b\u5fc3\u30a8\u30b3\u30fc\u306e\u7d50\u679c\uff0c\u6709\u52b9\u6027\u306b\u3064\u3044\u3066. \u7b2c23\u56de\u65e5\u672c\u8001\u5e74\u6b6f\u79d1\u533b\u5b66\u4f1a\uff08\u7b51\u6ce2\uff092012\u5e746\u6708<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u5742\u7530 \u5065\u4e00\u90ce, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5916\u304b\u3089\u518d\u5efa\u7528\u30d7\u30ec\u30fc\u30c8\u56fa\u5b9a\u3092\u884c\u3063\u305f\u7121\u6b6f\u984e\u306e\u4e21\u5074\u4e0b\u984e\u9aa8\u4f53\u90e8\u9aa8\u6298\u306e1\u4f8b. \u7b2c14\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u65b0\u6f5f\uff092012\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b711\u5dfb1\u53f7 Page34(2012.06)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u77f3\u5ddd \u4fee\u5e73, \u6a0b\u7530 \u6cf0\u6d69, \u79cb\u5c71 \u5ee3\u8f14, \u9593\u77f3 \u5948\u6e56, \u5ddd\u672c \u6cf0\u8f14, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u8ee2\u79fb\u80fd\u306e\u7570\u306a\u308b\u816b\u760d\u7531\u6765\u306e\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u7279\u6027\u89e3\u6790. \u7b2c28\u56de\u65e5\u672cDDS\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092012\u5e747\u6708 \u65e5\u672cDDS\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u4e88\u7a3f\u96c628\u56de Page173(2012.06)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u67f3\u5ddd\uff0d\u677e\u7530 \u5f69, \u9032\u85e4 \u6b63\u4fe1\uff1a\u767a\u304c\u3093\u6d3b\u6027\u3092\u6301\u3064pp32r1\u306fRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30afHuR\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b. \u7b2c23\u56de\u65e5\u672c\u81e8\u5e8a\u53e3\u8154\u75c5\u7406\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092012\u5e748\u6708<\/p>\n\n\n\n

\u5927\u5185 \u5b66, \u702c\u5ddd \u5353, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u9577\u8c37\u90e8 \u6643, \u5317\u5ddd \u5584\u653f, \u67f4\u7530 \u5065\u4e00\u90ce\uff1aToll-like receptor\u306e\u767a\u73fe\u30fb\u6a5f\u80fd\u306a\u3089\u3073\u306bNK\u6d3b\u6027\u306e\u52a0\u9f62\u5909\u5316\u3068\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3068\u306e\u95a2\u9023\u6027. \u7b2c79\u56de\u65e5\u672c\u7d30\u83cc\u5b66\u4f1a\u5317\u6d77\u9053\u652f\u90e8\u5b66\u8853\u7dcf\u4f1a\uff08\u5e2f\u5e83\uff092012\u5e748\u6708 \u8981\u65e8\u96c6 P30<\/p>\n\n\n\n

\u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u9aa8\u524a\u3092\u8981\u3059\u308b\u4e0b\u984e\u57cb\u4f0f\u667a\u629c\u6b6f\u5f8c\u306e\u75bc\u75db\u306e\u63a8\u79fb\u3068\u93ae\u75db\u5264\u670d\u7528\u72b6\u6cc1\uff5e\u7b2c1\u5831\uff5e. \u7b2c65\u56de\u5317\u6d77\u9053\u6b6f\u79d1\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092012\u5e748\u6708<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u6839\u6cbb\u56f0\u96e3\u306a\u9032\u884c\u984e\u53e3\u8154\u764c \u3069\u3053\u307e\u3067\u6cbb\u7642\u3059\u308b\u306e\u304b. \u7b2c64\u56de\u5317\u6d77\u9053\u6b6f\u79d1\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092012\u5e748\u6708<\/p>\n\n\n\n

\u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u53e3\u8154\u30b1\u30a2\u306b\u96e3\u6e0b\u3057\u305f\u30af\u30ed\u30a4\u30c4\u30d5\u30a7\u30eb\u30c8\u30fb\u30e4\u30b3\u30d6\u75c5\u306e\u4e00\u75c7\u4f8b. \u7b2c17\u56de\u30fb18\u56de\u65e5\u672c\u6442\u98df\u56a5\u4e0b\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u5b66\u4f1a\uff08\u672d\u5e4c\uff092012\u5e748\u6708<\/p>\n\n\n\n

\u64ad\u78e8 \u7f8e\u6a39, \u6ff1\u7530 \u6d69\u7f8e, \u9ce5\u5c45 \u3061\u3055\u307b, \u91d1\u5b50 \u771f\u68a8, \u4f50\u85e4 \u5065\u5f66, \u5c0f\u91ce \u8ca2\u4f38, \u6797 \u5229\u5f66, \u5c71\u5d0e \u88d5, \u912d \u6f22\u5fe0\uff1a\u4e0b\u984e\u533a\u57df\u5207\u9664\u75c7\u4f8b\u306e\u9aa8\u518d\u5efa\u5f8c\u306e\u7fa9\u6b6f\u88c5\u7740\u306b\u3088\u308b\u5480\u56bc\u30fb\u56a5\u4e0b\u6a5f\u80fd\u306e\u6539\u5584\u306b\u3064\u3044\u3066. \u7b2c17\u56de\u30fb18\u56de\u5171\u50ac\u65e5\u672c\u6442\u98df\u56a5\u4e0b\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092012\u5e748\u6708 \u6284\u9332\u96c6P.S348<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u5c71\u672c \u548c\u5e78, \u6a0b\u7530 \u6cf0\u6d69, \u79cb\u5c71 \u5ee3\u8f14, \u9593\u77f3 \u5948\u6e56, \u5ddd\u672c \u6cf0\u8f14, \u5317\u5c71 \u548c\u5b50, \u5927\u6fa4 \u5d07\u5b8f, \u5e73\u91ce \u8061, \u7be0\u539f \u4fe1\u96c4, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306b\u304a\u3051\u308bBiglycan\u306e\u6a5f\u80fd\u89e3\u6790(Biglycan is a specific marker and an autocrine angiogenic factor of tumor endothelial cells). \u7b2c71\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092012\u5e749\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b71\u56de Page86(2012.08)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u5317\u6751 \u54f2\u4e5f, \u67f3\u5ddd \u5f69, \u9032\u85e4 \u6b63\u4fe1, \u6771\u91ce \u53f2\u88d5\uff1app32r1\u306fRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30afHuR\u3068\u7d50\u5408\u3057\u305d\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b(pp32r1 binds to RNA binding protein HuR to prevent its cleavage). \u7b2c71\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092012\u5e749\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b71\u56de Page442(2012.08)<\/p>\n\n\n\n

\u795e\u90e8 \u82b3\u5247, \u5ddd\u8fba \u826f\u4e00, \u4f0a\u6771 \u5927\u5178, \u5317\u5ddd \u5584\u653f, \u524d\u7530 \u521d\u5f66, \u5c71\u672c \u54f2\u4e5f, \u53c8\u8cc0 \u6cc9, \u8349\u9593 \u5e79\u592b, \u85e4\u6797 \u5b5d\u53f8, \u5c71\u6839 \u6e90\u4e4b, \u4e2d\u6751 \u8aa0\u53f8, \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u7528\u8a9e\u30fb\u5206\u985e\u691c\u8a0e\u59d4\u54e1\u4f1a\uff1a\u81ea\u5df1\u514d\u75ab\u6027\u6c34\u75b1\u75c7\u306e\u5206\u985e\u6848. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c22\u56de\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092012\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c18\u5dfb2\u53f7 Page89(2012.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c26\u5dfb1\u53f7 Page106(2013.02)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u982c\u90e8\u306e\u76ae\u4e0b\u7d44\u7e54\u306b\u767a\u75c7\u3057\u305f\u8102\u80aa\u7d44\u7e54\u708e\u69d8T\u7d30\u80de\u30ea\u30f3\u30d1\u816b\u306e1\u4f8b. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c22\u56de\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092012\u5e749\u6708 \u6284\u9332 P19 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c18\u5dfb2\u53f7 Page93(2012.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c26\u5dfb1\u53f7 Page110(2013.02)<\/p>\n\n\n\n

\u64ad\u78e8 \u7f8e\u6a39, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u9577\u671f\u670d\u7528\u9ad8\u9f62\u8005\u306b\u751f\u3058\u305f\u91cd\u75c7\u7c98\u819c\u708e\u306e1\u4f8b. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c22\u56de\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092012\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c18\u5dfb2\u53f7 Page105(2012.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c26\u5dfb1\u53f7 Page122(2013.02)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u5742\u7530 \u5065\u4e00\u90ce, \u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u79e6 \u6d69\u4fe1, \u6c34\u8c37 \u7be4\u53f2, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053\u5927\u5b66\u75c5\u9662\u53e3\u8154\u5185\u79d1\u306b\u304a\u3051\u308b\u5473\u899a\u7570\u5e38\u60a3\u8005210\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c22\u56de\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092012\u5e749\u6708 \u6284\u9332 P23 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c18\u5dfb2\u53f7 Page108(2012.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c26\u5dfb1\u53f7 Page125(2013.02)<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5185\u79d1\u3068\u6b6f\u79d1\u5fc3\u8eab\u533b\u7642 \u5317\u5927\u306b\u304a\u3051\u308bOral Medicine(\u53e3\u8154\u5185\u79d1)\u3068\u6b6f\u79d1\u5fc3\u8eab\u75c7\u306e\u73fe\u72b6\u3068\u8ab2\u984c. \u7b2c27\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5ddd\u8d8a\uff092012\u5e749\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1-2\u53f7 Page71(2012.12)<\/p>\n\n\n\n

\u5c71\u5d0e \u88d5, \u6751\u4e95 \u77e5\u4f73, \u6751\u7530 \u7ffc, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u5185\u306b\u306f\u4f55\u3082\u306a\u3044\u306e\u306b\u5473\u899a\u7570\u5e38\u3092\u8a34\u3048\u308b\u81ea\u767a\u6027\u7570\u5e38\u5473\u899a\u306b\u304a\u3051\u308b\u5fc3\u7406\u7684\u56e0\u5b50\u306e\u691c\u8a0e. \u7b2c27\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5ddd\u8d8a\uff092012\u5e749\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1-2\u53f7 Page73(2012.12)<\/p>\n\n\n\n

\u6751\u4e95 \u77e5\u4f73, \u5c71\u5d0e \u88d5, \u6751\u7530 \u7ffc, \u5317\u5ddd \u5584\u653f\uff1aSSRI\u304c\u594f\u52b9\u3057\u305f\u767a\u75c7\u65e9\u671f\u306e\u975e\u5b9a\u578b\u6b6f\u75db\u306e2\u4f8b. \u7b2c27\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5ddd\u8d8a\uff092012\u5e749\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1-2\u53f7 Page83(2012.12)<\/p>\n\n\n\n

\u963f\u90e8 \u572d\u543e, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5742\u7530 \u5065\u4e00\u90ce, \u6751\u7530 \u7ffc, \u5317\u5ddd \u5584\u653f\uff1a\u975e\u5b9a\u578b\u6b6f\u75db\u306b\u5bfe\u3059\u308bSSRI\u3068\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u7cfb\u6297\u4e0d\u5b89\u85ac\u306e\u4f75\u7528\u7642\u6cd5. \u7b2c27\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5ddd\u8d8a\uff092012\u5e749\u6708 \u6284\u9332 P39 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1-2\u53f7 Page94(2012.12)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4e2d\u6751 \u88d5\u4ecb, \u6751\u4e95 \u77e5\u4f73, \u5317\u5ddd \u5584\u653f\uff1a\u5473\u899a\u969c\u5bb3\u60a3\u8005\u306b\u5bfe\u3059\u308b\u30ed\u30d5\u30e9\u30bc\u30d6\u9178\u30a8\u30c1\u30eb\u306e\u52b9\u679c. \u7b2c27\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5ddd\u8d8a\uff092012\u5e749\u6708 \u6284\u9332 P61 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1-2\u53f7 Page103(2012.12)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u67f3\u5ddd\uff0d\u677e\u7530 \u5f69, \u9032\u85e4 \u6b63\u4fe1\uff1a\u767a\u304c\u3093\u6d3b\u6027\u3092\u6301\u3064pp32r1\u306fHuR\u3068\u7d50\u5408\u3057\u305d\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b. \u7b2c92\u56de\u5317\u6d77\u9053\u533b\u5b66\u5927\u4f1a\u816b\u760d\u7cfb\u5206\u79d1\u4f1a\uff08\u7b2c106\u56de\u5317\u6d77\u9053\u764c\u8ac7\u8a71\u4f1a\u4f8b\u4f1a\uff09\uff08\u672d\u5e4c\uff092012\u5e749\u6708<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ed2\u5d8b \u96c4\u5fd7, \u5317\u5ddd \u6804\u4e8c\uff1a\u4e0b\u984e\u533a\u57df\u5207\u9664\u306b\u304a\u3051\u308b\u9aa8\u7247\u4f4d\u518d\u73fe\u306e\u5de5\u592b.\u5e73\u621024\u5e74\u7b2c3\u56de\u4f8b\u4f1a\u3000\u5317\u6d77\u9053\u75c5\u9662\u6b6f\u79d1\u533b\u4f1a\uff08\u5317\u6d77\u9053\uff092012\u5e749\u6708<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u91ce\u8c37 \u5065\u4e00, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u5409\u5ddd \u548c\u4eba, \u5317\u5ddd \u5584\u653f\uff1a\u82e5\u5e74\u8005\u306e\u6162\u6027\u4e0b\u984e\u9aa8\u9aa8\u9ac4\u708e(Garre\u2019s\u9aa8\u9ac4\u708e)\u306e1\u4f8b. \u7b2c57\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6a2a\u6d5c\uff092012\u5e749\u6708<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u5c71\u5d0e \u88d5, \u6751\u4e95 \u77e5\u4f73, \u4e2d\u6751 \u88d5\u4ecb, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u6700\u8fd1\u5f53\u79d1\u3067\u7d4c\u9a13\u3057\u305f\u975e\u5b9a\u578b\u6b6f\u75db\u75c7\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c57\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6a2a\u6d5c\uff092012\u5e7410\u6708<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u8d85\u97f3\u6ce2\u9aa8\u30e1\u30b9\u3092\u4f7f\u7528\u3057\u4e0b\u6b6f\u69fd\u795e\u7d4c\u8840\u7ba1\u675f\u3078\u306e\u4fb5\u8972\u3092\u6e1b\u3058\u305f\u4e0b\u984e\u679d\u77e2\u72b6\u5206\u5272\u8853\u306e\u75c7\u4f8b. \u7b2c57\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092012\u5e7410\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5317\u6751 \u54f2\u4e5f, \u5ca1\u672c \u7965\u4e09, \u5fd7\u8cc0 \u54f2, \u670d\u90e8 \u76f4\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u7389\u6728 \u9577\u826f, \u5317\u5ddd \u5584\u653f\uff1aFMISO PET\u306f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u7d44\u7e54\u5185\u306eHIF-1\u03b1\u306e\u767a\u73fe\u3092\u53cd\u6620\u3059\u308b. \u7b2c52\u56de\u65e5\u672c\u6838\u533b\u5b66\u56de\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\u5e02\uff092012\u5e7410\u6708 \u6838\u533b\u5b6649\u5dfb3\u53f7 Page S175(2012.08)<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u984e\u9aa8\u75c5\u5909\u306e\u6838\u533b\u5b66 \u984e\u9aa8\u75be\u60a3\u306b\u304a\u3051\u308b\u6838\u533b\u5b66\u5fdc\u7528\u306e\u53ef\u80fd\u6027. \u7b2c52\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7410\u6708 \u6838\u533b\u5b6649\u5dfb3\u53f7 Page S179(2012.08)<\/p>\n\n\n\n

\u7af9\u5185 \u5eb7\u4eba, \u72ac\u4f0f \u6b63\u5e78, \u6751\u4e95 \u77e5\u4f73, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f, \u4f50\u8cc0 \u6052\u592b\uff1aNa+\/I-\u5171\u8f38\u9001\u30bf\u30f3\u30d1\u30af\u3092\u7528\u3044\u305f\u4f4e\u9178\u7d20\u5fdc\u7b54\u306e\u5206\u5b50\u907a\u4f1d\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0. \u7b2c52\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7410\u6708 \u6838\u533b\u5b6649\u5dfb3\u53f7 Page S196(2012.08)<\/p>\n\n\n\n

\u72ac\u4f0f \u6b63\u5e78, \u7af9\u5185 \u5eb7\u4eba, \u6751\u4e95 \u77e5\u4f73, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f, \u4f50\u8cc0 \u6052\u592b\uff1a\u30de\u30a6\u30b9\u81ea\u7136\u767a\u751f\u809d\u8ee2\u79fb\u30e2\u30c7\u30eb\u306eSPECT\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0. \u7b2c52\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7410\u6708 \u6838\u533b\u5b6649\u5dfb3\u53f7 Page S265(2012.08)<\/p>\n\n\n\n

\u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u9ad8\u9f62\u8005\u8853\u524d\u691c\u67fb\u306b\u304a\u3051\u308b\u5fc3\u30a8\u30b3\u30fc\u306e\u7d50\u679c\u306b\u3064\u3044\u3066. \u7b2c40\u56de\u65e5\u672c\u6b6f\u79d1\u9ebb\u9154\u5b66\u4f1a\uff08\u535a\u591a\uff092012\u5e7410\u6708<\/p>\n\n\n\n

\u53e4\u6a4b \u4e00\u61b2, \u8d64\u5742 \u53f8, \u5317\u5ddd \u5584\u653f, \u4e98\u7406 \u6587\u592b\uff1a\u30d2\u30c83D\u76ae\u819a\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u751f\u4f53\u6750\u6599\u3000\u4e0a\u76ae\u9593\u306e\u5c01\u9396\u6027\u8a55\u4fa1. \u7b2c60\u56de\u65e5\u672c\u6b6f\u79d1\u7406\u5de5\u5b66\u4f1a\u5b66\u8853\u8b1b\u6f14\u4f1a\uff08\u535a\u591a\uff092012\u5e7410\u6708 \u65e5\u672c\u6b6f\u79d1\u7406\u5de5\u5b66\u4f1a\u8a8c31\u5dfb5\u53f7 Page392(2012.09)<\/p>\n\n\n\n

Satoh A, Sugiura C, Hata H, Sato J, Notani K, Kitagawa Y : Usefulness of free vascularized bone reconstruction for advanced mandibular osteoradionecrosis. ACOMS 2012 (Bali), 2012.11<\/p>\n\n\n\n

Sato J, Satoh T, Abe T, Satoh A, Imamachi K, Kitagawa Y : Difficulty in diagnosis of tetanus in Japan; Review of the literature. 10th Asian Congress on Oral and Maxillofacial Surgeons (Bali), 2012.11 Abstract P180<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5916\u79d1\u9818\u57df\u306b\u304a\u3051\u308bHBO\u306e\u9069\u5fdc\u3068\u6709\u7528\u6027. \u7b2c47\u56de\u65e5\u672c\u9ad8\u6c17\u5727\u74b0\u5883\u30fb\u6f5c\u6c34\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7411\u6708 \u65e5\u672c\u9ad8\u6c17\u5727\u74b0\u5883\u30fb\u6f5c\u6c34\u533b\u5b66\u4f1a\u96d1\u8a8c47\u5dfbSuppl. Page26(2012.09)<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7, \u5317\u5ddd \u6804\u4e8c\uff1a\u9aa8\u7c97\u9b06\u75c7\u3092\u5bfe\u8c61\u3068\u3057\u305fBRONJ\u75c7\u4f8b\u306e\u5448\u793a. \u5e73\u621024\u5e74\u7b2c4\u56de\u4f8b\u4f1a\u3000\u5317\u6d77\u9053\u75c5\u9662\u6b6f\u79d1\u533b\u4f1a\u5b66\u8853\u8b1b\u6f14\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7411\u6708<\/p>\n\n\n\n

\u5927\u5185 \u5b66\uff1aToll-like receptors\u306e\u767a\u73fe\u30fb\u6a5f\u80fd\u306a\u3089\u3073\u306bNK\u6d3b\u6027\u306e\u52a0\u9f62\u5909\u5316\u3068\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3068\u306e\u95a2\u9023\u6027. \u5e73\u621024\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c (0914-7063)33\u5dfb2\u53f7 Page201(2013.03)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb\uff1a\u767a\u304c\u3093\u6d3b\u6027\u3092\u6301\u3064pp32r1\u306fHuR\u3068\u7d50\u5408\u3057\u305d\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b. \u5e73\u621024\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092012\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c33\u5dfb2\u53f7 Page203(2013.03)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u67f3\u5ddd\uff0d\u677e\u7530 \u5f69, \u9032\u85e4 \u6b63\u4fe1\uff1a\u767a\u304c\u3093\u6d3b\u6027\u3092\u6301\u3064pp32r1\u306fHuR\u3068\u7d50\u5408\u3057\u305d\u306e\u5206\u89e3\u3092\u6291\u5236\u3059\u308b. \u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\uff08\u798f\u5ca1\uff092012\u5e7412\u6708<\/p>\n\n\n\n

\u5e73\u621025\u5e74\uff082013\u5e74\uff09<\/p>\n\n\n\n

\u53e4\u6a4b \u4e00\u61b2, \u5317\u5ddd \u5584\u653f, \u8d64\u5742 \u53f8, \u4e98\u7406 \u6587\u592b, \u9752\u6cbc \u4ec1\u5fd7\uff1a\u30d2\u30c8\u4e0a\u76ae3\u6b21\u5143\u57f9\u990a\u7d44\u7e54\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u751f\u4f53\u6750\u6599-\u8edf\u7d44\u7e54\u9593\u306e\u5c01\u9396\u6027\u8a55\u4fa1. \u7b2c25\u56de\u4ee3\u7528\u81d3\u5668\u30fb\u518d\u751f\u533b\u5b66\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092013\u5e742\u6708 \u5317\u6d77\u9053\u5916\u79d1\u96d1\u8a8c58\u5dfb1\u53f7 Page87-88(2013.06)<\/p>\n\n\n\n

\u5927\u5185 \u5b66, \u4f50\u4f2f \u6b69, \u67f4\u7530 \u5065\u4e00\u90ce\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3068\u52a0\u9f62\u306b\u304a\u3051\u308bToll\u69d8\u53d7\u5bb9\u4f53\u3068NK\u6d3b\u6027\u306e\u767a\u73fe\u3068\u6a5f\u80fd(Expression and function of Toll-like receptors and NK activity in oral candidiasis and aging). \u7b2c86\u56de\u65e5\u672c\u7d30\u83cc\u5b66\u4f1a\u7dcf\u4f1a\uff08\u5343\u8449\uff092013\u5e743\u6708 \u65e5\u672c\u7d30\u83cc\u5b66\u96d1\u8a8c 68\u5dfb1\u53f7 Page223(2013.02)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u5927\u5185 \u5b66, \u5317\u5ddd \u5584\u653f\uff1a\u7fa9\u6b6f\u306b\u5b9a\u7740\u3057\u305f\u30ab\u30f3\u30b8\u30c0\u83cc\u306b\u5bfe\u3059\u308b3\u5ba4\u578b\u96fb\u89e3\u6a5f\u80fd\u6c34(\u9ad8\u9178\u6027\u6c34\u3001\u9ad8\u9084\u5143\u6c34)\u306e\u9664\u83cc\u52b9\u679c. \u7b2c24\u56de\u65e5\u672c\u53e3\u8154\u6a5f\u80fd\u6c34\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092013\u5e743\u6708 \u6284\u9332 P50-51 \u65e5\u672c\u53e3\u8154\u6a5f\u80fd\u6c34\u5b66\u4f1a\u8a8c14\u5dfb1\u53f7 Page50-51(2013.03)<\/p>\n\n\n\n

Fatema CN, \u8d99 \u677e\u5409, \u8d99 \u82ab, \u6751\u4e0a \u6b63\u7d18, \u4e8e \u805e\u6587, \u897f\u5d8b \u5263\u4e00, \u7389\u6728 \u9577\u826f, \u5317\u5ddd \u5584\u653f, \u4e45\u4e0b \u88d5\u53f8\uff1a\u653e\u5c04\u7dda\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u816b\u760d\u5897\u6b96\u53cd\u5fdc\u306e18F-FLT\u306b\u3088\u308b\u8a55\u4fa1\u3000\u30d2\u30c8\u982d\u9838\u90e8\u764c\u79fb\u690d\u30e2\u30c7\u30eb\u52d5\u7269\u306b\u304a\u3051\u308bKi-67\u3068\u306e\u6bd4\u8f03\u691c\u8a0e. \u65e5\u672c\u85ac\u5b66\u4f1a\u7b2c133\u5e74\u4f1a\uff08\u6a2a\u6d5c\uff092013\u5e743\u6708 \u65e5\u672c\u85ac\u5b66\u4f1a\u5e74\u4f1a\u8981\u65e8\u96c6133\u5e74\u4f1a2\u53f7 Page273(2013.03)<\/p>\n\n\n\n

\u5927\u5185 \u5b66, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aToll-like receptors\u306e\u767a\u73fe\u30fb\u6a5f\u80fd\u306a\u3089\u3073\u306bNK\u6d3b\u6027\u3068\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3068\u306e\u95a2\u9023\u6027. \u7b2c67\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6803\u6728\uff092013\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb1\u53f7 Page73-74(2014.01)<\/p>\n\n\n\n

\u53e4\u6a4b \u4e00\u61b2, \u5317\u5ddd \u5584\u653f\uff1a\u30d2\u30c83\u6b21\u5143\u4e0a\u76ae\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u6750\u6599\u4e0a\u76ae\u7d44\u7e54\u9593\u306e\u5c01\u9396\u6027\u8a55\u4fa1. \u7b2c67\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6803\u6728\uff092013\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb1\u53f7 Page74(2014.01)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u6771\u91ce \u53f2\u88d5, \u5317\u6751 \u54f2\u4e5f, \u677e\u7530 \u5f69, \u5317\u5ddd \u5584\u653f, \u9032\u85e4 \u6b63\u4fe1\uff1app32r1\u306fHuR\u3068\u7d50\u5408\u3057\u30af\u30ea\u30d9\u30fc\u30b8\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u7d30\u80de\u304c\u3093\u5316\u8a98\u5c0e\u306b\u306f\u305f\u3089\u304f. \u7b2c67\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6803\u6728\uff092013\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb1\u53f7 Page121(2014.01)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u6c34\u8c37 \u7be4\u53f2, \u5317\u5ddd \u5584\u653f\uff1a\u8840\u6e05\u4e9c\u925b\u5024\u306f\u5fc5\u305a\u3057\u3082\u5473\u899a\u969c\u5bb3\u3092\u53cd\u6620\u3057\u306a\u3044. \u7b2c67\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6803\u6728\uff092013\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb1\u53f7 Page132(2014.01)<\/p>\n\n\n\n

Fatema CN, \u8d99 \u677e\u5409, \u8d99 \u82ab, \u6751\u4e0a \u6b63\u7d18, \u4e8e \u805e\u6587, \u897f\u5d8b \u5263\u4e00, \u7389\u6728 \u9577\u826f, \u5317\u5ddd \u5584\u653f, \u4e45\u4e0b \u7950\u53f8\uff1a\u982d\u9838\u90e8\u764c\u7570\u7a2e\u79fb\u690d\u7247\u306b\u304a\u3051\u308bFLT\u3092\u7528\u3044\u305f\u653e\u5c04\u7dda\u7642\u6cd5\u5f8c\u306eKi67\u306b\u3088\u308b\u816b\u760d\u5897\u6b96\u6d3b\u6027\u306e\u6bd4\u8f03(Monitoring tumor proliferative activity after radiotherapy by FLT in head and neck cancer xenograft comparison with Ki67). \u7b2c67\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6803\u6728\uff092013\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb1\u53f7 Page138(2014.01)<\/p>\n\n\n\n

\u52a0\u85e4 \u5353\u5df1, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u5927\u5185 \u5b66, \u5b88\u5c4b \u4fe1\u543e, \u698a\u539f \u5178\u5e78, \u5317\u5ddd \u5584\u653f\uff1a\u5728\u5b85\u81ea\u7acb\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u83cc\u306e\u4fdd\u83cc\u72b6\u614b\u306b\u95a2\u3059\u308b\u7e26\u65ad\u8abf\u67fb. \u7b2c67\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6803\u6728\uff092013\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb1\u53f7 Page166(2014.01)<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Asaka T, Hattori N, Okamoto S, Shiga T, Shindoh M, Tamaki N : FMISO-PET predicts the pre-operative chemotherapy response in patients with oral squamous cell carcinoma. 2013 SNMI annual meeting (Vancouver), 2013.6<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u75db\u75c7\u306b\u5bfe\u3059\u308b\u7acb\u52b9\u6563\u306e\u6709\u7528\u6027\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c39\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u76db\u5ca1\uff092013\u5e746\u6708 \u6284\u9332 P39<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5065\u5f66, \u6749\u6d66 \u5343\u5c0b, \u4ef2\u76db \u5efa\u6cbb, \u7af9\u5ddd \u653f\u7bc4, \u9ce5\u8c37\u90e8 \u7d14\u884c, \u524d\u7530 \u61b2\u662d, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053HIV\/AIDS\u6b6f\u79d1\u533b\u7642\u30cd\u30c3\u30c8\u30ef\uff0d\u30af\u69cb\u7bc9\u4e8b\u696d\u306e\u6982\u8981. \u7b2c51\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u90e8\u4f1a\uff08\u76db\u5ca1\uff092013\u5e746\u6708 \u6284\u9332P41<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30ea\u30c9\u30ab\u30a4\u30f3\u30a2\u30ec\u30eb\u30ae\u30fc\u304c\u7591\u308f\u308c\u305f\u60a3\u8005\u306e\u667a\u6b6f\u629c\u6b6f\u306e1\u4f8b. \u7b2c51\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u90e8\u4f1a\uff08\u76db\u5ca1\uff092013\u5e746\u6708<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u4f7f\u7528\u60a3\u8005\u306b\u304a\u3051\u308b\u4e0b\u984e\u518d\u5efa\u306e\u75c7\u4f8b. \u7b2c39\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u76db\u5ca1\uff092013\u5e746\u6708<\/p>\n\n\n\n

\u9234\u6728 \u5cfb\u4e00, \u79e6 \u6d69\u4fe1, \u64ad\u78e8 \u7f8e\u6a39, \u4f50\u85e4 \u660e, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a6\u6b73\u7537\u5150\u306e\u53f3\u4e0b\u984e\u5927\u81fc\u6b6f\u306b\u751f\u3058\u305f\u30a8\u30ca\u30e1\u30eb\u4e0a\u76ae\u7dda\u7dad\u6b6f\u7259\u816b\u306e1\u4f8b. \u7b2c39\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u76db\u5ca1\uff092013\u5e746\u6708<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u5c71\u5d0e \u88d5, \u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u30be\u30ec\u30c9\u30ed\u30f3\u9178\u306b\u3088\u308bBRONJ\u306b\u5bfe\u3059\u308b\u9ad8\u6c17\u5727\u9178\u7d20\u7642\u6cd5\u3068\u8150\u9aa8\u9664\u53bb\u8853\u306e\u4f75\u7528\u7642\u6cd5. \u7b2c\uff15\uff11\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u4f1a\u30fb\u7b2c\uff13\uff19\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u76db\u5ca1\uff092013\u5e746\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u6284\u9332\u96c6\uff15\uff15\u9801 (2013.06)<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u5317\u7530 \u79c0\u662d, \u5c71\u4e0b \u77e5\u5df3, \u698a\u539f \u5178\u5e78, \u5317\u5ddd \u5584\u653f, \u912d \u6f22\u5fe0, \u95a2\u5802 \u5145\uff1a\u8840\u7ba1\u67c4\u4ed8\u304d\u9aa8\u79fb\u690d\u306b\u3088\u308b\u4e0b\u984e\u518d\u5efa. \u7b2c37\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u6771\u4eac\uff092013\u5e746\u6708 \u982d\u90e8\u764c39\u5dfb2\u53f7 Page164(2013.05)<\/p>\n\n\n\n

\u4e09\u6cb3 \u6d0b\u5e73, \u4f50\u85e4 \u660e, \u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u91ce\u8c37 \u5065\u4e00, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u9aa8\u306b\u751f\u3058\u305f\u7d21\u9318\u7d30\u80de\u764c\u306e1\u4f8b. \u7b2c37\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u6771\u4eac\uff092013\u5e746\u6708 \u982d\u9838\u90e8\u764c39\u5dfb2\u53f7 Page227(2013.05)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u4e2d\u6751 \u88d5\u4ecb, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u4e80\u5d0e \u826f\u52a9, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u75db\u75c7\u306b\u5bfe\u3059\u308b\u5869\u9178\u30d1\u30ed\u30ad\u30bb\u30c1\u30f3\u9320\u306e\u52b9\u679c\u3068\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76. \u7b2c28\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092013\u5e747\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c28\u5dfb1-2\u53f7 Page43(2013.12)<\/p>\n\n\n\n

\u4e80\u5d0e \u826f\u52a9, \u5c71\u5d0e \u88d5, \u5742\u7530 \u5065\u4e00\u90ce, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30bb\u30cd\u30b9\u30c8\u30d1\u30c1\u30fc\u306e1\u4f8b. \u7b2c28\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092013\u5e747\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c28\u5dfb1-2\u53f7 Page46-47(2013.12)<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u4f50\u85e4 \u660e, \u6d45\u9999 \u5353\u54c9, \u9234\u6728 \u5cfb\u4e00, \u64ad\u78e8 \u7f8e\u6a39, \u5317\u5ddd \u5584\u653f\uff1aTransmasseteric antero-parotid approach(TMAP)\u3067\u884c\u3063\u305f\u95a2\u7bc0\u7a81\u8d77\u9aa8\u6298\u306e1\u4f8b. \u7b2c15\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u718a\u672c\uff092013\u5e747\u6708 \u6284\u9332 P71 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b712\u5dfb1\u53f7 Page68(2013.06)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u95a2\u7bc0\u7d50\u7bc0\u524a\u9664\u8853\u3092\u9069\u5fdc\u3057\u305f\u591a\u6570\u306e\u57fa\u790e\u75be\u60a3\u3092\u6709\u3059\u308b\u4e21\u5074\u7fd2\u6163\u6027\u984e\u95a2\u7bc0\u8131\u81fc\u306e1\u4f8b. \u7b2c26\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092013\u5e747\u6708 \u6284\u9332 P80 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c25\u5dfbSuppl. Page80(2013.07)<\/p>\n\n\n\n

\u5c71\u4e0b \u6620\u7f8e, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u6b6f\u78e8\u5264\u306b\u3088\u308b\u53e3\u5507\u306e\u63a5\u89e6\u76ae\u819a\u708e\u3068\u8003\u3048\u3089\u308c\u305f1\u4f8b. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c23\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092013\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c19\u5dfb2\u53f7 Page83(2013.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1\u53f7 Page84(2014.02)<\/p>\n\n\n\n

\u4e80\u5d0e \u826f\u52a9, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u553e\u6db2\u3068\u95a2\u9023\u3059\u308b\u75c7\u72b6\u3092\u8a34\u3048\u305f\u53e3\u8154\u5185\u30bb\u30cd\u30b9\u30c8\u30d1\u30c1\u30fc\u306e2\u4f8b. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c23\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092013\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c19\u5dfb2\u53f7 Page88(2013.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1\u53f7 Page89(2014.02)<\/p>\n\n\n\n

\u67f3\u8c37 \u7f8e\u6c99, \u5bae\u8170 \u660c\u660e, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u6cbb\u7642\u7d4c\u904e\u4e2d\u306b\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u95a2\u9023\u30ea\u30f3\u30d1\u5897\u6b96\u6027\u75be\u60a3\u3068\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u95a2\u9023\u984e\u9aa8\u9aa8\u58ca\u6b7b\u3092\u4f75\u767a\u3057\u305f1\u4f8b. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u30fb\u7b2c23\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092013\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c19\u5dfb2\u53f7 Page101(2013.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c27\u5dfb1\u53f7 Page102(2014.02)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u9577\u8c37\u5ddd \u667a\u9999, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1abisphosphonate\u6295\u4e0e\u4e2d\u6b62\u5f8c\u306e\u9aa8\u306e\u7d30\u80de\u7fa4\u306b\u304a\u3051\u308b\u7d44\u7e54\u5316\u5b66\u7684\u691c\u7d22. \u7b2c55\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30fb\u7dcf\u4f1a\uff08\u5ca1\u5c71\uff092013\u5e749\u6708 Journal of Oral Biosciences Supplement2013\u5dfb Page134(2013.09)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u9577\u8c37\u5ddd \u667a\u9999, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1abisphosphonate\u6295\u4e0e\u4e2d\u6b62\u5f8c\u306e\u9aa8\u306e\u7d30\u80de\u7fa4\u306b\u304a\u3051\u308b\u7d44\u7e54\u5316\u5b66\u7684\u691c\u7d22. \u7b2c55\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30fb\u7dcf\u4f1a\uff08\u5ca1\u5c71\uff092013\u5e749\u6708 Journal of Oral Biosciences Supplement2013\u5dfb Page140(2013.09)<\/p>\n\n\n\n

\u7551\u702c \u6b63\u5c1a, \u5357 \u662d\u5b50, \u85e4\u6fa4 \u771f\u4e00, \u6f81\u8c37 \u6589, \u6e05\u6c34 \u529b, \u5317\u5ddd \u5584\u653f\uff1a\u91d1\u5c5e\u6210\u5206\u5206\u6790\u88c5\u7f6eNITON XL3t-800\u306e\u5c0e\u5165\u3068\u4f7f\u7528\u7d4c\u9a13. \u7b2c88\u56de\u5317\u6d77\u9053\u533b\u5b66\u691c\u67fb\u5b66\u4f1a\uff08\u5317\u898b\uff092013\u5e749\u6708 \u5317\u81e8\u6280\u4f1a\u8a8c11\u5dfb2\u53f7 Page35(2013.08)<\/p>\n\n\n\n

Sato J, Yamazaki Y, Satoh A, Notani K, Kitagawa Y : Continued monitoring of salivary interleukin-6 levels may predict early and late locoregional recurrence in patients with oral squamous cell carcinoma. 21st International Conference on Oral and Maxillofacila Surgery (Barcelona), 2013.10 Abstract P104<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u4f4e\u30bf\u30f3\u30d1\u30af\u8840\u75c7\u3092\u4f34\u3063\u305f\u30a8\u30ca\u30e1\u30eb\u4e0a\u76ae\u816b\u306e\u4e00\u4f8b. \u7b2c58\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\uff08\u535a\u591a\uff092013\u5e7410\u6708<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u6751\u4e95 \u77e5\u4f73, \u963f\u90e8 \u8cb4\u6d0b, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1aFDG-PET\/CT\u3092\u7528\u3044\u305f\u53e3\u8154\u764c\u8853\u524d\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u691c\u51fa\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c58\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\uff08\u535a\u591a\uff092013\u5e7410\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u963f\u90e8 \u8cb4\u6d0b, \u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u5c71\u5d0e \u88d5, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aFDG-PET\u306f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u8853\u524d\u5316\u5b66\u7642\u6cd5\u306e\u7d44\u7e54\u5b66\u7684\u52b9\u679c\u3092\u53cd\u6620\u3059\u308b. \u7b2c58\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092013\u5e7410\u6708 \u6284\u9332 P245<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u75c7\u72b6\u3092\u5448\u3057\u305f\u6297BP180\u578b\u7c98\u819c\u985e\u5929\u75b1\u7621\u306e2\u4f8b. \u7b2c58\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092013\u5e7410\u6708<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u6d45\u9999 \u5353\u54c9, \u5bae\u8170 \u660c\u660e, \u5c71\u5d0e \u88d5, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u3067\u7d4c\u9a13\u3057\u305f\u653e\u5c04\u7dda\u6027\u984e\u9aa8\u58ca\u6b7b\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c58\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092013\u5e7410\u6708 \u6284\u9332 P320<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u5c71\u5d0e \u88d5, \u5c0f\u91ce\u5bfa \u9ebb\u8a18\u5b50, \u5409\u5ddd \u548c\u4eba, \u5bae\u8170 \u660c\u660e, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u60aa\u6027\u816b\u760d\u60a3\u8005\u306b\u304a\u3051\u308b\u6ce8\u5c04\u7528BMA\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u306e\u4e88\u9632\u3068\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u5f53\u79d1\u306e\u53d6\u308a\u7d44\u307f. \u7b2c58\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092013\u5e7410\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6 P63<\/p>\n\n\n\n

\u9234\u6728 \u5cfb\u4e00, \u7af9\u5185 \u591a\u7f8e\u4ee3, \u6709\u99ac \u592a\u90ce\uff1a\u54ac\u5408\u9762\u9593\u8ddd\u96e2\u304c\u6700\u5927\u4e0b\u54ac\u5408\u529b\u767a\u63ee\u4e2d\u306e\u5480\u56bc\u7b4b\u96fb\u6c17\u7684\u6d3b\u52d5\u91cf\u306b\u4e0e\u3048\u308b\u5f71\u97ff. \u65e5\u672c\u88dc\u7db4\u6b6f\u79d1\u5b66\u4f1a\u5e73\u621025\u5e74\u5ea6\u6771\u4eac\u652f\u90e8\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092013\u5e7410\u6708<\/p>\n\n\n\n

\u7af9\u5185 \u5eb7\u4eba, \u72ac\u4f0f \u6b63\u5e78, \u6751\u4e95 \u77e5\u4f73, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f, \u4f50\u8cc0 \u6052\u592b\uff1a\u816b\u760d\u5185\u306e\u4f4e\u9178\u7d20\u907a\u4f1d\u5b50\u5fdc\u7b54\u3068\u4f4e\u9178\u7d20PET\u30c8\u30ec\u30fc\u30b5\u96c6\u7a4d\u306e\u95a2\u4fc2. \u7b2c53\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u535a\u591a\uff092013\u5e7411\u6708 \u6838\u533b\u5b6650\u5dfb3\u53f7 Page S210(2013.09)<\/p>\n\n\n\n

\u4e8e \u805e\u6587, \u8d99 \u677e\u5409, \u6751\u4e0a \u6b63\u7d18, \u8d99 \u82ab, Fatema CN, \u897f\u5d8b \u5263\u4e00, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f, \u4e45\u4e0b \u88d5\u53f8\uff1a\u6297\u8840\u7ba1\u65b0\u751f\u5264(sorafenib)\u306e\u6297\u816b\u760d\u52b9\u679c\u306e\u6a5f\u5e8f\u3000\u80ba\u764c\u7d30\u80de\u79fb\u690d\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308bFMISO\u306b\u3088\u308b\u816b\u760d\u5185\u9178\u7d20\u72b6\u614b\u306e\u8a55\u4fa1. \u7b2c53\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u535a\u591a\uff092013\u5e7411\u6708 \u6838\u533b\u5b6650\u5dfb3\u53f7 Page S212(2013.09)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u5c71\u5d0e \u88d5, \u5ca1\u672c \u7965\u4e09, \u5fd7\u8cc0 \u54f2, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f\uff1aFDG-PET\u3092\u7528\u3044\u305f\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u306b\u5bfe\u3059\u308b\u9ad8\u5727\u9178\u7d20\u7642\u6cd5\u306e\u6709\u52b9\u6027\u306e\u8a55\u4fa1. \u7b2c53\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u535a\u591a\uff092013\u5e7411\u6708 \u6838\u533b\u5b6650\u5dfb3\u53f7 Page S240(2013.09)<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5ca1\u672c \u7965\u4e09, \u5fd7\u8cc0 \u54f2, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f\uff1aFDG-PET\/CT\u3092\u7528\u3044\u305f\u53e3\u8154\u764c\u8853\u524d\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u691c\u51fa\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c53\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u535a\u591a\uff092013\u5e7411\u6708 \u6838\u533b\u5b6650\u5dfb3\u53f7 Page S240(2013.09)<\/p>\n\n\n\n

\u5e73\u621026\u5e74\uff082014\u5e74\uff09<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ed2\u5d8b \u96c4\u5fd7, \u9032\u85e4 \u6b63\u4fe1\uff1a\u82e5\u5e74\u8005\u306b\u767a\u751f\u3057\u305f\u4e0a\u984e\u9aa8\u4e2d\u5fc3\u6027\u7c98\u8868\u76ae\u764c\u306e1\u4f8b. \u7b2c32\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\uff08\u672d\u5e4c\uff092014\u5e741\u6708<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u6d45\u9999 \u5353\u54c9, \u5409\u5ddd \u548c\u4eba, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1aFDG-PET\/CT\u3092\u7528\u3044\u305f\u53e3\u8154\u764c\u8853\u524d\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u691c\u51fa\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c32\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\uff08\u672d\u5e4c\uff092014\u5e741\u6708<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ed2\u5d8b \u96c4\u5fd7, \u677f\u6771 \u4f38\u5e78, \u5bae\u672c \u9855\u5f66, \u6b66\u5185 \u5468\u5e73, \u897f\u539f \u5e83\u53f2, \u8d64\u7fbd \u4fca\u7ae0\uff1aG-CSF\u7523\u751f\u816b\u760d\u304c\u7591\u308f\u308c\u305f\u820c\u764c\u306e1\u4f8b. \u7b2c40\u56de\u5317\u6d77\u9053\u982d\u9838\u90e8\u816b\u760d\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092014\u5e743\u6708<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u6295\u4e0e\u4e2d\u6b62\u5f8c\u306b\u304a\u3051\u308b\u9aa8\u306e\u7d30\u80de\u7fa4\u306e\u7d44\u7e54\u5316\u5b66\u7684\u691c\u7d22. \u7b2c119\u56de\u65e5\u672c\u89e3\u5256\u5b66\u4f1a\u7dcf\u4f1a\u5168\u56fd\u5b66\u8853\u5927\u4f1a\uff08\u6803\u6728\uff092014\u5e743\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6P109<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u9ed2\u5d8b \u96c4\u5fd7, \u5317\u5ddd \u6804\u4e8c\uff1a\u53e3\u8154\u518d\u5efa\u624b\u8853\u306b\u304a\u3051\u308b\u6297\u83cc\u85ac\u4f7f\u7528\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u5e73\u621026\u5e74\u5ea6\u5317\u6d77\u9053\u75c5\u9662\u6b6f\u79d1\u533b\u4f1a\u7b2c\uff11\u56de\u4f8b\u4f1a\u81e8\u5e8a\u691c\u8a0e\u4f1a\uff08\u672d\u5e4c\uff092014\u5e743\u6708<\/p>\n\n\n\n

Miyakoshi M, Yanagiya M, Sato J, Hata H, Sato C, Yamazaki Y, Kitagawa Y : Concurrence of MTX-LPD and BRONJ in patient with rheumatoid arthritis. American Academy of Oral Medicine Annual Meeting ( Orlando), 2014.4<\/p>\n\n\n\n

Miyakoshi M, Murai C, Abe T, Hata H, Satoh A, Yamazaki Y, Kitagawa Y, Shiga T, Tamaki N : Value and limitation of preoperative lymph node staging using FDG PET\/CT in patients with oral cancer: Comparison with histological findings. American Academy of Oral Medicine Annual Meeting ( Orlando), 2014.4<\/p>\n\n\n\n

Sakata K, Yamazaki Y, Ohga N, Sato J, Ohuchi M, Kitagawa Y : Clinical efficacy of Japanese traditional medicine for patients with glossodynia. American Academy of Oral Medicine Annual Meeting ( Orlando), 2014.4<\/p>\n\n\n\n

Oouchi M, Hata H, Yamazaki Y, Hasebe A, Shibata K, Kitagawa Y : Function of Toll-like receptors and natural killer activity in candidiasis. American Academy of Oral Medicine Annual Meeting ( Orlando), 2014.4<\/p>\n\n\n\n

\u7af9\u5185 \u5eb7\u4eba, \u72ac\u4f0f \u6b63\u5e78, \u6751\u4e95 \u77e5\u4f73, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f, \u4f50\u8cc0 \u6052\u592b\uff1a\u816b\u760d\u5185\u306e\u4f4e\u9178\u7d20\u907a\u4f1d\u5b50\u5fdc\u7b54\u3068\u4f4e\u9178\u7d20PET\u30c8\u30ec\u30fc\u30b5\u30fc\u96c6\u7a4d\u306e\u95a2\u4fc2. \u7b2c9\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092014\u5e745\u6708 JSMI Report7\u5dfb2\u53f7 Page68(2014.05)<\/p>\n\n\n\n

\u5927\u5185 \u5b66, \u5c71\u5d0e \u88d5, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aToll-like receptors\u306e\u767a\u73fe\u30fb\u6a5f\u80fd\u306a\u3089\u3073\u306bNK\u6d3b\u6027\u3068\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3068\u306e\u95a2\u9023\u6027. \u7b2c68\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092014\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c (0029-0297)63\u5dfb1\u53f7 Page73-74(2014.01)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u8fd1\u85e4 \u7f8e\u5f25\u5b50, \u79cb\u5c71 \u5ee3\u8f14, \u9593\u77f3 \u5948\u6e56, \u5317\u5ddd \u5584\u653f, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u816b\u760d\u5185\u4f4e\u9178\u7d20\u74b0\u5883\u3068\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306e\u7570\u5e38\u6027\u306e\u95a2\u9023. \u7b2c68\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092014\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb4\u53f7 Page347(2014.09)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u9ad8\u91ce \u660c\u58eb, \u5317\u5ddd \u6804\u4e8c, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308bmRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30afSam68\u306e\u767a\u73fe\u69d8\u5f0f\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u691c\u8a0e. \u7b2c68\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092014\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb4\u53f7 Page385(2014.09)<\/p>\n\n\n\n

\u6749\u5c71 \u6b63\u535a, \u4f50\u4f2f \u6b69, \u9577\u8c37\u90e8 \u6643, \u5317\u5ddd \u5584\u653f, \u67f4\u7530 \u5065\u4e00\u90ce\uff1a\u53e3\u8154\u30de\u30a4\u30b3\u30d7\u30e9\u30ba\u30de\u306eIL-1\u03b2\u7523\u751f\u8a98\u5c0e\u6d3b\u6027. \u7b2c68\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092014\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb4\u53f7 Page405(2014.09)<\/p>\n\n\n\n

\u7af9\u5185 \u5eb7\u4eba, \u72ac\u4f0f \u6b63\u5e78, \u6751\u4e95 \u77e5\u4f73, \u79e6 \u6d69\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u3055\u307e\u3056\u307e\u306a\u4f4e\u9178\u7d20\u6761\u4ef6\u306b\u304a\u3051\u308b\u4f4e\u9178\u7d20\u5fdc\u7b54\u9818\u57df\u306b\u3088\u308b\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u8a55\u4fa1. \u7b2c68\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092014\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb4\u53f7 Page420(2014.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5409\u5ddd \u548c\u4eba, \u5927\u8cc0 \u5247\u5b5d, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306e\u6cbb\u7642\u5f8c\u306e\u553e\u6db2\u4e2d\u306eIL-6\u6fc3\u5ea6\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306f\u5c40\u6240\u518d\u767a\u306e\u4e88\u6e2c\u306b\u6709\u7528\u3067\u3042\u308b. \u7b2c68\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092014\u5e745\u6708 \u6284\u9332 P332 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c63\u5dfb4\u53f7 Page448(2014.09)<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Miyakoshi M, Asaka T, Hattori N, Okamoto S, Shiga T, Shindoh M, Tamaki N : FMISO-PET reflects the ability of cell proliferation in oral squamous cell carcinoma. 2014 SNM annual meeting 2014 (St. Louis), 2014.6 Abstract P171<\/p>\n\n\n\n

Takeuchi Y, Inubushi M, Jin YN, Nagatsu K, Tsuji AB, Murai C, Hata H, Kitagawa Y, Saga T : Simultaneous PET\/SPECT imaging to compare tumor uptake level of 18F-FMISO with 64Cu-ATSM on the basis of the genetic activation level responding to tumor hypoxia. 2014 SNM annual meeting (St. Louis), 2014.6<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u7e54\u7530 \u516c\u5149, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u9023\u65e5\u6295\u4e0e\u306b\u3088\u308b\u9aa8\u82bd\u7d30\u80de\u30fb\u9aa8\u7d30\u80de\u3078\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066. \u7b2c34\u56de \u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\uff08\u672d\u5e4c\uff092014\u5e746\u6708 \u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\u96d1\u8a8c24\u5dfb2\u53f7 Page S114(2014.05)<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u7279\u767a\u6027\u553e\u6db2\u817a\u578b\u9ad8\u30a2\u30df\u30e9\u30fc\u30bc\u8840\u75c7\u306e1\u4f8b. \u7b2c40\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u79cb\u7530\uff092014\u5e746\u6708<\/p>\n\n\n\n

\u6e05\u6c34 \u516d\u82b1, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u5927\u8cc0 \u5247\u5b5d, \u571f\u5c4b \u6075\u674e\u4f73, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd\u3000\u5584\u653f\uff1a\u5c0f\u5150\u306b\u307f\u3089\u308c\u305f\u6025\u6027\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u306e\uff11\u4f8b. \u7b2c40\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u79cb\u7530\uff092014\u5e746\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u6b6f\u79d1\u306b\u304a\u3051\u308b\u5c40\u6240\u9ebb\u9154\u85ac\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u983b\u5ea6\u30fb\u539f\u56e0\u306a\u3069\u306b\u95a2\u3059\u308b\u691c\u8a0e\u3000Review. \u7b2c40\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u79cb\u7530\uff092014\u5e746\u6708 \u6284\u9332 P47 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c65\u5dfb2\u53f7 Page166(2016.07)<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u5065\u5f66\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u30a8\u30ca\u30e1\u30eb\u4e0a\u76ae\u816b\u306e\u6cbb\u7642\u6cd5.\u7b2c40\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff0c\u7b2c52\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u90e8\u4f1a\uff08\u79cb\u7530\uff092014\u5e746\u6708<\/p>\n\n\n\n

Asaka T, Fatema CN, Hata H, Sato J, Kitagawa Y : The effect of Hyperbaric oxygen therapy for bisphosphonate-related osteonecrosis of jaws (BRONJ). 9th Scientific Meeting of the Asian Academy of Osseointegration (Sapporo), 2014.7<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u7e54\u7530 \u516c\u5149, \u7db2\u585a \u61b2\u751f\uff1a\u9aa8\u82bd\u7d30\u80de\u304a\u3088\u3073\u9aa8\u7d30\u80de\u306b\u5bfe\u3059\u308b\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u9023\u65e5\u6295\u4e0e\u306e\u7d44\u7e54\u5316\u5b66\u7684\u4f5c\u7528. \u7b2c32\u56de\u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092014\u5e747\u6708 \u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u6284\u9332\u96c632\u56de Page293(2014.07)<\/p>\n\n\n\n

\u5c71\u4e0b \u6620\u7f8e, \u4f50\u85e4 \u5343\u6674, \u5927\u8cc0 \u5247\u5b5d, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u9818\u57df\u306b\u304a\u3051\u308b\u7570\u7269\u8ff7\u5165\u306e3\u4f8b. \u7b2c16\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u7c73\u5b50\uff092014\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b713\u5dfb1\u53f7 Page44(2014.11)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c0f\u7b20\u539f \u5229\u884c, \u4f50\u91ce \u548c\u751f, \u5317\u5ddd \u5584\u653f\uff1a\u4ea4\u611f\u795e\u7d4c\u5207\u9664\u304c\u6210\u9577\u671f\u306e\u30a6\u30b5\u30ae\u306e\u54ac\u7b4b\u306b\u304a\u3088\u307c\u3059\u5f71\u97ff\u306b\u3064\u3044\u3066. \u7b2c27\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092014\u5e747\u6708 \u6284\u9332 P119 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c26\u5dfbSuppl. Page111(2014.07)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u7279\u767a\u6027\u306a\u3089\u3073\u306b\u5fc3\u56e0\u6027\u5473\u899a\u969c\u5bb3\u60a3\u8005\u306b\u5bfe\u3059\u308b\u30ed\u30d5\u30e9\u30bc\u30d6\u9178\u30a8\u30c1\u30eb\u306e\u52b9\u679c\u3000\u5473\u899a\u969c\u5bb3\u60a3\u8005\u306b\u5bfe\u3059\u308b\u30ed\u30d5\u30e9\u30bc\u30d6\u9178\u30a8\u30c1\u30eb\u306e\u52b9\u679c. \u7b2c29\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a(\u6a2a\u6d5c)2014\u5e747\u6708 \u6284\u9332P52 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c29\u5dfb2\u53f7 Page95-96(2014.12)<\/p>\n\n\n\n

Satoh A, Hata H, Miyakoshi M, Yoshikawa K, Sato J, Kitagawa Y : Clinicopathological investigation of selective neck dissection( Level I~IV). AAOMS 2014 (Honolulu), 2014.9<\/p>\n\n\n\n

Asaka T, Hata H, Sato J, Satoh A, Miyakoshi M, Kitagawa Y : The Usefulness of FDG-PET for Monitoring Hyperbaric Oxygen Therapy in Treatment of Bisphosphonate-Related Osteonecrosis of Jaws (BRONJ). AAOMS 96th Annual Meeting (Honolulu), 2014.9<\/p>\n\n\n\n

Miyakoshi M, Yoshikawa K, Asaka T, Hata, H, Sato J, Satoh A, Kitagawa Y : Methotrexate associated Oral diseases. Lymphoproliferative disorder and severe stomatitis. AAOMS 96th Annual Meeting (Honolulu), 2014.9<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Asaka T, Miyakoshi M, Shindoh M : Advantage of FMISO-PET over FDG-PET for predicting histological response to preoperative chemotherapy in patients with oral squamous cell carcinoma. AAOMS 96th Annual Meeting 2014 (Honolulu), 2014.9<\/p>\n\n\n\n

Sato J, Kitagawa Y, Yamazaki Y, Hata H, Miyakoshi M, Asaka T, Ohga N, Hattori N, Okamoto S, Shiga T, Shindoh M, Tamaki N : FMISO-PET reflects the ability of cell proliferation in oral squamous cell carcinoma. The 12th international symposium for future drug discovery and medical care (Sapporo), 2014.9<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5185\u79d1\u6559\u80b2\u30fb\u8a3a\u7642\u306e\u73fe\u72b6\u3068\u8ab2\u984c \u53e3\u8154\u5185\u79d1\u3092\u62c5\u5f53\u3057\u306610\u5e74\u306e\u7d4c\u9a13\u304b\u3089. \u7b2c27\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u7b2c24\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5408\u540c\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092014\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c20\u5dfb2\u53f7 Page60(2014.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c28\u5dfb1\u53f7 Page51(2015.02)<\/p>\n\n\n\n

\u5c71\u4e0b \u6620\u7f8e, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u77f3\u5ddd \u8aa0, \u5c71\u5d0e \u88d5, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1aLaugier-Hunziker-Baran\u75c7\u5019\u7fa4\u3068\u8003\u3048\u3089\u308c\u305f5\u4f8b. \u7b2c27\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u7b2c24\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5408\u540c\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092014\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c20\u5dfb2\u53f7 Page84(2014.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c28\u5dfb1\u53f7 Page75(2015.02)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5409\u5ddd \u548c\u4eba, \u5927\u8cc0 \u5247\u5b5d, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u660e, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u982c\u7c98\u819c\u306b\u751f\u3058\u305f\u7d30\u83cc\u306b\u95a2\u9023\u3057\u305f\u3068\u601d\u308f\u308c\u308b\u767d\u8272\u75c5\u5909\u306e1\u4f8b. \u7b2c24\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c27\u56de\u533b\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092014\u5e749\u6708 \u6284\u9332P74 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c20\u5dfb2\u53f7 Page68(2014.12)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u8fd1\u85e4 \u7f8e\u5f25\u5b50, \u79cb\u5c71 \u5ee3\u8f14, \u9593\u77f3 \u5948\u6e56, \u5317\u5ddd \u5584\u653f, \u6a0b\u7530 \u6cf0\u6d69, \u9032\u85e4 \u6b63\u4fe1, \u6a0b\u7530 \u4eac\u5b50\uff1a\u816b\u760d\u5185\u4f4e\u9178\u7d20\u74b0\u5883\u3068\u816b\u760d\u8840\u7ba1\u5185\u76ae\u306e\u7570\u5e38\u6027\u306e\u95a2\u9023(Hypoxia-Induced Reactive Oxygen Species Cause Chromosomal Abnormalities in Endothelial Cells in the Tumor Microenvironment). \u7b2c73\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092014\u5e749\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b73\u56de Page J-1005(2014.09)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u524d\u7530 \u6d69\u6b21\u90ce, \u685c\u4e95 \u5e0c, \u6881 \u73ca\u73ca, \u4e2d\u6fa4 \u8aa0\u591a\u6717, \u5409\u5c71 \u88d5\u898f, \u67f3\u539f \u4e94\u5409, \u4e45\u4fdd \u8cb4\u7d00, \u5317\u5ddd \u5584\u653f, \u5ddd\u5185 \u79c0\u4e4b, \u6d5c\u7530 \u6df3\u4e00, \u98ef\u7b39 \u4e45\uff1aRNA\u7de8\u96c6\u9175\u7d20ADAR2\u306f\u60aa\u6027\u80f8\u819c\u4e2d\u76ae\u816b\u7d30\u80de\u306e\u5897\u6b96\u30fb\u904b\u52d5\u30fb\u6d78\u6f64\u6027\u3092\u5236\u5fa1\u3059\u308b(A to I RNA-editing enzyme, ADAR2, regulates cell proliferation, motility and invasion in human mesothelioma cells). \u7b2c73\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092014\u5e749\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b73\u56de Page J-2091(2014.09)<\/p>\n\n\n\n

\u4e2d\u6fa4 \u8aa0\u591a\u6717, \u98ef\u7b39 \u4e45, \u6881 \u73ca\u73ca, \u5409\u5ddd \u548c\u4eba, \u67cf\u5d0e \u6674\u5f66, \u5317\u5ddd \u5584\u653f, \u5c71\u5d0e \u88d5, \u6d5c\u7530 \u6df3\u4e00\uff1a\u5909\u7570\u578bp53R248Q\u3068R248W\u306e\u30d2\u30c8\u53e3\u8154\u304c\u3093\u7d30\u80de\u306e\u60aa\u6027\u5f62\u8cea\u306b\u304a\u3088\u307c\u3059\u5f71\u97ff(Comparison of gain-of-function effects between the p53 mutants R248Q and R248W in human oral cancer cells). \u7b2c73\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092014\u5e749\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b73\u56de Page J-2078(2014.09)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u9577\u8c37\u5ddd \u667a\u9999, \u864e\u8c37 \u5f4c, \u7e54\u7530 \u516c\u5149, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u9023\u65e5\u6295\u4e0e\u4e2d\u30fb\u6295\u4e0e\u4e2d\u6b62\u5f8c\u306b\u304a\u3051\u308b\u9aa8\u306e\u7d30\u80de\u7fa4\u306b\u304a\u3051\u308b\u7d44\u7e54\u5316\u5b66\u7684\u5909\u5316. \u7b2c56\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30fb\u7dcf\u4f1a\uff08\u535a\u591a\uff092014\u5e749\u6708 Journal of Oral Biosciences Supplement2014\u5dfb Page106(2014.09)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u3005\u6728 \u5b97\u8f1d, \u9577\u8c37\u5ddd \u667a\u9999, \u864e\u8c37 \u5f4c, \u7e54\u7530 \u516c\u5149, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u9023\u65e5\u6295\u4e0e\u4e2d\u30fb\u6295\u4e0e\u4e2d\u6b62\u5f8c\u306b\u304a\u3051\u308b\u9aa8\u306e\u7d30\u80de\u7fa4\u306b\u304a\u3051\u308b\u7d44\u7e54\u5316\u5b66\u7684\u5909\u5316. \u7b2c56\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30fb\u7dcf\u4f1a\uff08\u535a\u591a\uff092014\u5e749\u6708 Journal of Oral Biosciences Supplement2014\u5dfb Page139(2014.09)<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u9ed2\u5d8b \u96c4\u5fd7\uff1aBRONJ\u5f53\u79d1\u3067\u884c\u3063\u3066\u3044\u308b\u5bfe\u5fdc. \u5e73\u621026\u5e74\u5ea6\u5317\u6d77\u9053\u75c5\u9662\u6b6f\u79d1\u533b\u4f1a\u7b2c3\u56de\u4f8b\u4f1a\u81e8\u5e8a\u691c\u8a0e\u4f1a\uff08\u51fd\u9928\uff092014\u5e749\u6708<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u5065\u5f66, \u9ad8\u91ce \u660c\u58eb, \u9032\u85e4 \u6b63\u4fe1, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u984e\u9aa8\u4e2d\u5fc3\u6027\u764c\u3068\u8003\u3048\u3089\u308c\u305f3\u4f8b\u306b\u3064\u3044\u3066\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c59\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092014\u5e7410\u6708<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90de, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u9ed2\u5d8b \u96c4\u5fd7\uff1a\u820c\u5589\u982d\u5168\u6458\u60a3\u8005\u306b\u304a\u3051\u308b\u56a5\u4e0b\u6a5f\u80fd\u306e\u691c\u8a0e. \u7b2c59\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092014\u5e7410\u6708<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u4f50\u85e4 \u660e, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1aFDG-PET\u3092\u7528\u3044\u305f\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u306b\u5bfe\u3059\u308b\u9ad8\u5727\u9178\u7d20\u7642\u6cd5\u306e\u6709\u52b9\u6027\u306e\u8a55\u4fa1. \u7b2c59\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a(\u5e55\u5f35)2014\u5e7410\u6708<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u53e4\u5ddd \u5eb7\u5e73, \u6751\u4e95 \u77e5\u4f73, \u767e\u5408\u8349 \u5065\u572d\u5fd7\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u88fd\u5264\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b(BRONJ)35\u4f8b\u306e\u7d30\u83cc\u5b66\u7684\u691c\u8a0e. \u7b2c59\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092014\u5e7410\u6708<\/p>\n\n\n\n

\u8d99 \u677e\u5409, Fatema CN, \u8d99 \u82ab, \u4e8e \u805e\u6587, \u897f\u5d8b \u5263\u4e00, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f, \u4e45\u4e0b \u88d5\u53f8\uff1a\u982d\u9838\u90e8\u764c\u306b\u304a\u3051\u308b\u653e\u5c04\u7dda\u7167\u5c04\u5f8c\u306e\u816b\u760d\u5897\u6b96\u53cd\u5fdc\u3068\u816b\u760d\u5185\u4f4e\u9178\u7d20\u72b6\u614b\u306e\u7d4c\u6642\u7684\u5909\u5316 FMISO\u3068FLT\u306b\u3088\u308b\u8a55\u4fa1. \u7b2c54\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u5927\u962a\uff092014\u5e7411\u6708 \u6838\u533b\u5b6651\u5dfb3\u53f7 Page280(2014.09)<\/p>\n\n\n\n

\u4e8e \u805e\u6587, \u8d99 \u677e\u5409, \u8d99 \u82ab, Fatema CN, \u897f\u5d8b \u5263\u4e00, \u5317\u5ddd \u5584\u653f, \u7389\u6728 \u9577\u826f, \u4e45\u4e0b \u88d5\u53f8\uff1a\u6297\u8840\u7ba1\u65b0\u751f\u5264(sorafenib)\u306e\u6297\u816b\u760d\u52b9\u679c\u306e\u6a5f\u5e8f \u814e\u7d30\u80de\u764c\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b18F-FMISO\u306b\u3088\u308b\u816b\u760d\u5185\u9178\u7d20\u72b6\u614b\u306e\u8a55\u4fa1. \u7b2c54\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u5927\u962a\uff092014\u5e7411\u6708 \u6838\u533b\u5b6651\u5dfb3\u53f7 Page281(2014.09)<\/p>\n\n\n\n

\u67cf\u5d0e \u6674\u5f66, \u6751\u7530 \u52dd, \u5317\u5ddd \u5584\u653f, \u77f3\u5ddd \u8aa0\uff1a\u4e0a\u984e\u56a2\u80de\u6458\u51fa\u90e8\u306b\u81ea\u5bb6\u8131\u7070\u8c61\u7259\u8cea\u9846\u7c92\u304a\u3088\u3073\u6b6f\u306e\u5373\u6642\u79fb\u690d\u3092\u884c\u3063\u305f1\u4f8b. \u7b2c18\u56de\u65e5\u672c\u984e\u9854\u9762\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5cf6\u6839\uff092014\u5e7411\u6708 Japanese Journal of Maxillo Facial Implants13\u5dfb3\u53f7 Page157(2014.11)<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u897f\u6c5f \u6e09, \u6c0f\u5bb6 \u82f1\u4e4b, \u6cc9 \u5065\u592a\u90ce, \u5ca9\u7530 \u6d69\u660e, \u590f\u8cc0 \u5065, \u6e05\u6c34 \u5b8f, \u5317\u5ddd \u5584\u653f\uff1a\u6c34\u75b1\u6027\u985e\u5929\u75b1\u7621\u81ea\u5df1\u6297\u539f\u3067\u3042\u308b17\u578b\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u7570\u306a\u308b\u30a8\u30d4\u30c8\u30fc\u30d7\u306b\u5bfe\u3059\u308b\u6297\u4f53\u306e\u75c5\u539f\u6027\u89e3\u6790. \u5e73\u621026\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092014\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c35\u5dfb2\u53f7 Page188(2015.03)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u524d\u7530 \u6d69\u6b21\u90ce, \u685c\u4e95 \u5e0c, \u4e2d\u6fa4 \u8aa0\u591a\u6717, \u9805 \u6167\u6167, \u6881 \u73ca\u73ca, \u5409\u5c71 \u88d5\u898f, \u67f3\u539f \u4e94\u5409, \u4e45\u4fdd \u8cb4\u7d00, \u5ddd\u5185 \u79c0\u4e4b, \u6d5c\u7530 \u6df3\u4e00, \u98ef\u7b39 \u4e45, \u5317\u5ddd \u5584\u653f\uff1aRNA\u7de8\u96c6\u9175\u7d20ADAR2\u306e\u767a\u73fe\u6291\u5236\u306f\u60aa\u6027\u4e2d\u76ae\u816b\u7d30\u80de\u306e\u60aa\u6027\u5ea6\u3092\u4f4e\u4e0b\u3055\u305b\u308b. \u5e73\u621026\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092014\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c35\u5dfb2\u53f7 Page189(2015.03)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50\uff1a\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u9023\u65e5\u6295\u4e0e\u304a\u3088\u3073\u6295\u4e0e\u4e2d\u6b62\u304c\u9aa8\u82bd\u7d30\u80de\u30fb\u9aa8\u7d30\u80de\u306b\u4e0e\u3048\u308b\u7d44\u7e54\u5316\u5b66\u7684\u5f71\u97ff. \u5e73\u621026\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092014\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c35\u5dfb2\u53f7 Page193(2015.03)<\/p>\n\n\n\n

Wada M, Nishie W, Ujiie H, Izumi K, Iwata H, Natsuga K, Kitagawa Y, Shimizu H : Epitope-dependent pathogenicity of antibodies to collagen XVII\/BP180 for blister formation. The 39th annual Meeting of the Japanese Society for Investigative Dermatology (Osaka), 2014.12<\/p>\n\n\n\n

\u5e73\u621027\u5e74\uff082015\u5e74\uff09<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u6d45\u9999 \u5353\u54c9, \u6e05\u6c34 \u516d\u82b1, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u764c\u306e\u8840\u7ba1\u67c4\u4ed8\u904a\u96e2\u76ae\u5f01\u518d\u5efa\u8853\u5f8c\u306b\u751f\u3058\u305f\u4e2d\u5fc3\u9759\u8108\u30ab\u30c6\u30fc\u30c6\u30eb\u95a2\u9023\u6df1\u90e8\u9759\u8108\u8840\u6813\u75c7\u306e2\u4f8b. \u7b2c33\u56de\u3000\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\uff08\u5948\u826f\uff092015\u5e741\u6708<\/p>\n\n\n\n

\u6e05\u6c34 \u516d\u82b1, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u6d45\u9999 \u5353\u4e5f, \u5317\u6751 \u54f2\u4e5f, \u4f50\u85e4 \u660e, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0a\u984e\u9aa8\u306b\u767a\u75c7\u3057\u305f\u5de8\u5927\u306a\u6b6f\u539f\u6027\u7c98\u6db2\u816b\u306e1\u4f8b. \u7b2c33\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a \u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5948\u826f\uff092015\u5e741\u6708 \u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c633\u5dfbPage229 (2015)<\/p>\n\n\n\n

\u53e4\u6a4b \u4e00\u61b2, \u5317\u5ddd \u5584\u653f, \u5409\u6751 \u4ec1\u5fd7, \u4f50\u91ce \u548c\u751f\uff1a\u86cd\u5149\u30a8\u30c3\u30af\u30b9\u7dda\u5206\u6790\u3068\u8efd\u5143\u7d20\u30b5\u30f3\u30d7\u30ea\u30f3\u30b0\u30c4\u30fc\u30eb\u3092\u7528\u3044\u305f\u53e3\u8154\u5185\u6b6f\u79d1\u7528\u5408\u91d1\u306e\u9ad8\u7cbe\u5ea6\u30fb\u9ad8\u901f\u5206\u6790. \u7b2c34\u56de\u65e5\u672c\u53e3\u8154\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u5b66\u4f1a\u8fd1\u757f\u30fb\u5317\u9678\u652f\u90e8\u5b66\u8853\u5927\u4f1a\uff08\u4eac\u90fd\uff092015\u5e741\u6708 \u65e5\u672c\u53e3\u8154\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u5b66\u4f1a\u8a8c28\u5dfb4\u53f7 Page536(2015.12)<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u79e6 \u6d69\u4fe1, \u5409\u5ddd \u548c\u4eba, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u820c\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u6cbb\u7642\u6210\u7e3e. \u5317\u6d77\u9053\u982d\u9838\u90e8\u816b\u760d\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092015\u5e742\u6708<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u9aa8\u30fb\u8edf\u9aa8\u79fb\u884c\u90e8\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u306b\u5bfe\u3059\u308b\u8d85\u5fae\u7d30\u69cb\u9020\u5f62\u614b\u7684\u8a55\u4fa1. \u7b2c120\u56de\u65e5\u672c\u89e3\u5256\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5168\u56fd\u5b66\u8853\u96c6\u4f1a\u30fb\u7b2c92\u56de\u65e5\u672c\u751f\u7406\u5b66\u4f1a\u5927\u4f1a\u5408\u540c\u5927\u4f1a\uff08\u795e\u6238\uff092015\u5e743\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6\uff1aS187 (2015.03)<\/p>\n\n\n\n

\u5b87\u4f50\u7f8e \u96c4\u53f8, \u5317\u5ddd \u5584\u653f, \u9577\u5742 \u6d69, \u9ad8\u6728 \u5f8b\u7537, \u5bae\u7530 \u52dd, \u67f4 \u79c0\u6a39, \u5409\u5ddd \u535a\u653f\uff1a\u672c\u90a6\u306b\u304a\u3051\u308bHIV\u611f\u67d3\u8005\u306e\u6b6f\u79d1\u533b\u7642\u4f53\u5236\u69cb\u7bc9\u6d3b\u52d5\u306b\u3064\u3044\u3066. \u7b2c24\u56de\u65e5\u672c\u6709\u75c5\u8005\u6b6f\u79d1\u533b\u7642\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u65ed\u5ddd\uff092015\u5e743\u6708 \u6709\u75c5\u8005\u6b6f\u79d1\u533b\u764224\u5dfb4\u53f7 Page266-267(2015.12)<\/p>\n\n\n\n

Asaka T, Yamashita E, Ohga N, Ishikawa M, Shindoh M,\u3000Kitagawa Y : Five cases of Laugier-Hunziker-Baran syndrome. COLLABORATION IN DIAGNOSTIC SCIENCES San Diego 2015 Hosted by the American Academy of Oral Medicine and the American Academy of Oral & Maxillofacial Pathology (San Diego), 2015.4<\/p>\n\n\n\n

Wada M, Nishie W, Ujiie H, Izumi K, Iwata H, Natsuga K, Shimizu H, Kitagawa Y : Epitope-dependent pathogenicity of antibodies targeting a major pemphigoid autoantigen, BP180. COLLABORATION IN DIAGNOSTIC SCIENCES San Diego 2015 Hosted by the American Academy of Oral Medicine and the American Academy of Oral & Maxillofacial Pathology (San Diego), 2015.4<\/p>\n\n\n\n

\u68ee\u672c \u771f\u5f18, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u306e\u9664\u83cc\u306b\u3088\u308a\u523a\u6fc0\u6642\u553e\u6db2\u91cf\u306f\u5897\u52a0\u3059\u308b. \u5317\u6d77\u9053\u53e3\u8154\u5185\u79d1\u7814\u7a76\u4f1a\uff08\u672d\u5e4c\uff092015\u5e744\u6708<\/p>\n\n\n\n

\u677e\u7530 \u5f69, \u5317\u6751 \u54f2\u4e5f, \u6771\u91ce \u53f2\u88d5, \u9ed2\u5d8b \u96c4\u5fd7, \u912d \u6731\u8499, \u30cf\u30d3\u30d0\u30fb\u30a6\u30f3\u30de, \u9032\u85e4 \u6b63\u4fe1\uff1a\u30a2\u30c7\u30ce\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u3088\u308bHuR\u306e\u6319\u52d5\u306f\u30a6\u30a4\u30eb\u30b9\u8907\u88fd\u3068\u95a2\u9023\u3059\u308b. \u7b2c104\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e744\u6708<\/p>\n\n\n\n

\u6749\u5c71 \u6b63\u535a, \u4f50\u4f2f \u6b69, \u9577\u8c37\u90e8 \u6643, \u4e80\u5d0e \u826f\u52a9, \u5317\u5ddd \u5584\u653f, \u67f4\u7530 \u5065\u4e00\u90ce\uff1a\u6a39\u72b6\u7d30\u80de\u306a\u3089\u3073\u306b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u304a\u3051\u308bMycoplasma salivarium\u306b\u3088\u308bNLRP3\u30a4\u30f3\u30d5\u30e9\u30de\u30bd\u30fc\u30e0\u306e\u6d3b\u6027\u5316. \u7b2c42\u56de\u65e5\u672c\u30de\u30a4\u30b3\u30d7\u30e9\u30ba\u30de\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u6771\u4eac\uff092015\u5e745\u6708 \u65e5\u672c\u30de\u30a4\u30b3\u30d7\u30e9\u30ba\u30de\u5b66\u4f1a\u96d1\u8a8c42\u53f7 Page50(2016.03)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5409\u5ddd \u548c\u4eba, \u5927\u8cc0 \u5247\u5b5d, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1aFMISO-PET\u3092\u7528\u3044\u305f\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u60a3\u8005\u306b\u304a\u3051\u308b\u4f4e\u9178\u7d20\u72b6\u614b\u306e\u81e8\u5e8a\u7684\u89e3\u6790. \u7b2c69\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7b2c9\u56de\u53e3\u8154\u984e\u9854\u9762\u6838\u533b\u5b66\u30d5\u30a9\uff0d\u30e9\u30e0\u5b66\u8853\u96c6\u4f1a\uff1a\u7279\u5225\u8b1b\u6f14\uff08\u5927\u962a\uff092015\u5e745\u6708 \u6284\u9332P155 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c64\u5dfb2\u53f7 Page101(2015.07)<\/p>\n\n\n\n

\u5742\u7530 \u5065\u4e00\u90ce, \u5409\u5ddd \u548c\u4eba, \u698a\u539f \u5178\u5e78, \u5317\u5ddd \u5584\u653f\uff1aRNA\u7de8\u96c6\u9175\u7d20ADAR2\u306e\u767a\u73fe\u6291\u5236\u306f\u60aa\u6027\u4e2d\u76ae\u816b\u7d30\u80de\u306e\u60aa\u6027\u5ea6\u3092\u4f4e\u4e0b\u3055\u305b\u308b. \u7b2c69\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092015\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c64\u5dfb2\u53f7 Page150(2015.07)<\/p>\n\n\n\n

\u6749\u5c71 \u6b63\u535a, \u4f50\u4f2f \u6b69, \u9577\u8c37\u90e8 \u6643, \u5317\u5ddd \u5584\u653f, \u67f4\u7530 \u5065\u4e00\u90ce\uff1aMycoplasma salivarium\u306b\u3088\u308b\u6a39\u72b6\u7d30\u80de\u306a\u3089\u3073\u306b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u304a\u3051\u308bNLRP3\u30a4\u30f3\u30d5\u30e9\u30de\u30bd\u30fc\u30e0\u6d3b\u6027\u5316. \u7b2c69\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092015\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c64\u5dfb2\u53f7 Page145(2015.07)<\/p>\n\n\n\n

\u5927\u5185 \u5b66, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u938c\u53e3 \u771f\u7531\u7f8e, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u91cd\u75c7\u5fc3\u8eab\u969c\u5bb3\u5150\u306b\u751f\u3058\u305f\u4e21\u5074\u4e0a\u984e\u9aa8\u6b63\u89d2\u5316\u6b6f\u539f\u6027\u56a2\u80de\u306e1\u4f8b. \u7b2c69\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092015\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c64\u5dfb2\u53f7 Page180-181(2015.07)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u5bae\u8170 \u660c\u660e, \u5143\u5ddd \u8ce2\u4e00\u90ce, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u3092\u7528\u3044\u305fCBA\u6cd5\u306b\u3088\u308b\u553e\u6db2\u4e2d\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u6e2c\u5b9a\u306e\u8a66\u307f\u3000\u5065\u5e38\u8005\u306b\u304a\u3051\u308b\u553e\u6db2\u3068\u8840\u6db2\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u6fc3\u5ea6\u306e\u6e2c\u5b9a. \u7b2c69\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092015\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c64\u5dfb2\u53f7 Page206(2015.07)<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u5317\u5ddd \u5584\u653f\uff1a\u6c34\u75b1\u6027\u985e\u5929\u75b1\u7621\u81ea\u5df1\u6297\u539f\u3067\u3042\u308bBP180\u306e\u7570\u306a\u308b\u30a8\u30d4\u30c8\u30fc\u30d7\u306b\u5bfe\u3059\u308b\u6297\u4f53\u306e\u75c5\u539f\u6027\u89e3\u6790. \u7b2c69\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u5927\u962a\uff092015\u5e745\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c64\u5dfb2\u53f7 Page220(2015.07)<\/p>\n\n\n\n

Sato J, Kitagawa Y, Watanabe S, Okamoto S, Ohga N, Asaka T, Miyakoshi M, Hata H, Hirata K, Hattori N , Shiga T, Shindoh M, Tamaki N : Hypoxic volume evaluated by FMISPO-PET reflects expression of HIF 1\u03b1 and Ki-67 in oral squamous cell carcinoma. 2015 SNMI Annual meeting (Baltimore), 2015.6 Abstract P128<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u539f\u53e3 \u771f\u8863, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u8edf\u9aa8\u5185\u9aa8\u5316\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u5fae\u7d30\u69cb\u9020\u5b66\u7684\u691c\u7d22. \u7b2c35\u56de\u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\uff08\u5009\u6577\uff092015\u5e746\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6\uff1aS22 (2015.06)<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u539f\u53e3 \u771f\u8863, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u8edf\u9aa8\u5185\u9aa8\u5316\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u5fae\u7d30\u69cb\u9020\u5b66\u7684\u691c\u7d22. \u7b2c35\u56de \u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\uff08\u5009\u6577\uff092015\u5e746\u6708 \u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\u96d1\u8a8c25\u5dfb2\u53f7 Page S72(2015.05)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u8349\u6df1 \u516c\u79c0, \u9b3c\u585a \u54f2\u90ce, \u4eca\u4e95 \u7be4\u5fd7, \u4e0a\u689d \u670b\u4e4b, \u98ef\u7530 \u5584\u5e78, \u767e\u5408\u8349 \u5065\u572d\u5fd7\uff1a\u65e9\u671f\u820c\u6241\u5e73\u4e0a\u76ae\u764c\u75c7\u4f8b\u306b\u304a\u3051\u308b\u5f8c\u767a\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u7fa4\u306e\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u691c\u8a0e. \u7b2c39\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c4\u56de\u30a2\u30b8\u30a2\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u795e\u6238\uff092015\u5e746\u6708 \u982d\u9838\u90e8\u764c41\u5dfb2\u53f7 Page213(2015.05)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u820c\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c39\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\u30fb\u7b2c4\u56de\u30a2\u30b8\u30a2\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u795e\u6238\uff092015\u5e746\u6708 \u982d\u9838\u90e8\u764c41\u5dfb2\u53f7 Page243(2015.05)<\/p>\n\n\n\n

\u938c\u53e3 \u771f\u7531\u7f8e, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308bMRONJ\u5916\u79d1\u75c7\u4f8b\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c41\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u3000\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092015\u5e746\u6708<\/p>\n\n\n\n

\u68ee\u672c \u771f\u5f18, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u306e\u9664\u83cc\u306b\u3088\u308a\u523a\u6fc0\u6642\u553e\u6db2\u91cf\u306f\u5897\u52a0\u3059\u308b. \u7b2c41\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092015\u5e746\u6708<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u4e95\u4e0a \u8fb2\u592b\u7537, \u8c37\u6751 \u6676\u5e83, \u9032\u85e4 \u6b63\u4fe1, \u7b95\u8f2a \u548c\u884c, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u5507\u306b\u767a\u75c7\u3057\u305f\u75a3\u8d05\u578b\u9ec4\u8272\u816b\u306e1\u4f8b. \u7b2c41\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092015\u5e746\u6708<\/p>\n\n\n\n

\u8c37\u6751 \u6676\u5e83, \u4e95\u4e0a \u8fb2\u592b\u7537, \u963f\u90e8 \u8cb4\u6d0b, \u7b95\u8f2a \u548c\u884c, \u9032\u85e4 \u6b63\u4fe1\uff1a\u7247\u5074\u54ac\u7b4b\u80a5\u5927\u3092\u4f34\u3046\u5480\u56bc\u7b4b\u8171\u30fb\u8171\u819c\u904e\u5f62\u6210\u75c7\u306e\u4e00\u4f8b. \u7b2c41\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092015\u5e746\u6708<\/p>\n\n\n\n

\u5357\u689d \u6c99\u8036\u52a0, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u592a\u5b50 \u82b3\u4ec1, \u6c34\u8d8a \u5b5d\u5178, \u5317\u5ddd \u5584\u653f\uff1a\u629c\u6b6f\u3092\u5951\u6a5f\u306b\u767a\u75c7\u3057\u305f\u300c\u305f\u3053\u3064\u307c\u578b\u5fc3\u7b4b\u75c7\u300d\u306e1\u4f8b. \u7b2c53\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u5730\u65b9\u90e8\u4f1a\u5b66\u8853\u96c6\u4f1a\u30fb\u7b2c41\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092015\u5e746\u6708<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6d45\u9999 \u96c4\u4e00\u90ce\uff1a\u8033\u7ba1\u72ed\u7a84\u3092\u5f15\u304d\u8d77\u3053\u3057\u305f\u5316\u81bf\u6027\u984e\u95a2\u7bc0\u708e\u306e1\u4f8b. \u7b2c53\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c41\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u3000\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u672d\u5e4c\uff092015\u5e746\u6708<\/p>\n\n\n\n

\u4e2d\u6fa4 \u8aa0\u591a\u6717, \u8fd1\u85e4 \u7f8e\u5f25\u5b50, \u5742\u7530 \u5065\u4e00\u90ce, \u5317\u5ddd \u5584\u653f, \u5c71\u5d0e \u88d5\uff1a\u820c\u75db\u75c7\u306e\u88dc\u52a9\u7642\u6cd5\u3068\u3057\u3066\u306e\u7acb\u52b9\u6563\u542b\u55fd\u306e\u8a66\u307f. \u7b2c30\u56de\u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u5b66\u4f1a\u8a2d\u7acb30\u5468\u5e74\u8a18\u5ff5\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092015\u5e747\u6708 \u65e5\u672c\u6b6f\u79d1\u5fc3\u8eab\u533b\u5b66\u4f1a\u96d1\u8a8c30\u5dfb2\u53f7 Page76-77(2015.12)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u75c5\u7684\u4e0b\u984e\u9aa8\u9aa8\u6298\u306e2\u4f8b. \u7b2c17\u56de\u65e5\u672c\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\uff08\u548c\u6b4c\u5c71\uff092015\u5e747\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5c0f\u7b20\u539f \u5229\u884c, \u4f50\u91ce \u548c\u751f, \u5317\u5ddd \u5584\u653f\uff1a\u4e0a\u9838\u795e\u7d4c\u7bc0\u5207\u9664\u306e\u52d5\u7269\u30e2\u30c7\u30eb\u306e\u78ba\u7acb\u3068\u30a6\u30b5\u30ae\u306e\u54ac\u7b4b\u306e\u7d44\u7e54\u5b66\u7684\u5909\u5316. \u7b2c28\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e747\u6708 \u6284\u9332P113 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c27\u5dfbSuppl. Page113(2015.07)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u672c\u90f7 \u88d5\u7f8e, \u9577\u8c37\u5ddd \u667a\u9999, \u5c71\u672c \u77e5\u771f\u4e5f\uff1a\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u6295\u4e0e\u5f8c\u306e\u9aa8\u7d30\u80de\u30fb\u9aa8\u7d30\u7ba1\u7cfb\u306e\u753b\u50cf\u89e3\u6790. \u7b2c33\u56de\u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092015\u5e747\u6708 \u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u6284\u9332\u96c633\u56de Page212(2015.07)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u75c5\u7684\u4e0b\u984e\u9aa8\u9aa8\u6298\u306e2\u4f8b. \u7b2c17\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u548c\u6b4c\u5c71\uff092015\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b714\u5dfb1\u53f7 Page45(2015.12)<\/p>\n\n\n\n

\u6c34\u91ce \u6674\u6a39, \u4f50\u85e4 \u6df3, \u5317\u68ee \u6b63\u543e, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u5343\u6674, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u65e9\u671f\u306b\u6b6f\u6839\u5185\u90e8\u5438\u53ce\u3092\u751f\u3058\u305f\u5916\u50b7\u6027\u6b6f\u7259\u8131\u81fc\u306e1\u4f8b(\u7b2c2\u5831) 7\u5e74\u9593\u306e\u7d4c\u904e\u89b3\u5bdf. \u7b2c17\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u548c\u6b4c\u5c71\uff092015\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b714\u5dfb1\u53f7 Page50(2015.12)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u672c\u90f7 \u88d5\u7f8e, \u9577\u8c37\u5ddd \u667a\u9999, \u7db2\u585a \u61b2\u751f\uff1a\u7cd6\u5c3f\u75c5\u304c\u9aa8\u7d30\u80de\u306b\u4e0e\u3048\u308b\u7d44\u7e54\u5316\u5b66\u7684\u5f71\u97ff\u306b\u3064\u3044\u3066\u3000SDT fatty\u30e9\u30c3\u30c8\u3092\u7528\u3044\u305f\u89e3\u6790. \u7b2c57\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30fb\u7dcf\u4f1a\uff08\u65b0\u6f5f\uff092015\u5e749\u6708 Journal of Oral Biosciences Supplement2015\u5dfb Page308(2015.09)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u672c\u90f7 \u88d5\u7f8e, \u9577\u8c37\u5ddd \u667a\u9999, \u7db2\u585a \u61b2\u751f\uff1a\u7cd6\u5c3f\u75c5\u304c\u9aa8\u7d30\u80de\u306b\u4e0e\u3048\u308b\u7d44\u7e54\u5316\u5b66\u7684\u5f71\u97ff\u306b\u3064\u3044\u3066\u3000SDT fatty\u30e9\u30c3\u30c8\u3092\u7528\u3044\u305f\u89e3\u6790. \u7b2c57\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\u30fb\u7dcf\u4f1a\uff08\u65b0\u6f5f\uff092015\u5e749\u6708 Journal of Oral Biosciences Supplement2015\u5dfb Page173(2015.09)<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u7db2\u585a \u61b2\u751f\uff1a\u8edf\u9aa8\u5185\u9aa8\u5316\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u5fae\u7d30\u69cb\u9020\u5b66\u7684\u691c\u7d22. \u7b2c57\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u65b0\u6f5f\uff092015\u5e749\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6\uff1a31, 172 (2015.09)<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u6e05\u6c34 \u516d\u82b1, \u938c\u53e3 \u771f\u7531\u7f8e, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u984e\u4e0b\u30ea\u30f3\u30d1\u7bc0\u306b\u307f\u3089\u308c\u305fIgG4\u95a2\u9023\u30ea\u30f3\u30d1\u7bc0\u75c7\u306e1\u4f8b. \u7b2c28\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092015\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c29\u5dfb1\u53f7 Page51(2016.02)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u67f3\u8c37 \u7f8e\u6c99, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u306e\u4e0d\u968f\u610f\u904b\u52d5\u3067\u30d7\u30c1\u30d7\u30c1\u97f3\u3092\u767a\u3059\u308b\u30aa\u30fc\u30e9\u30eb\u30b8\u30b9\u30ad\u30cd\u30b8\u30a2\u3068\u601d\u308f\u308c\u305f1\u4f8b. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092015\u5e749\u6708 \u6284\u9332P76 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c21\u5dfb2\u53f7 Page93(2015.12)<\/p>\n\n\n\n

\u5c71\u4e0b \u6620\u7f8e, \u79e6 \u6d69\u4fe1, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u30e1\u30c1\u30eb\u30b3\u30d0\u30e9\u30df\u30f3\u4f7f\u7528\u75c7\u4f8b\u306b\u95a2\u3059\u308b\u691c\u8a0e \u4e0b\u984e\u57cb\u4f0f\u667a\u6b6f\u629c\u6b6f\u3092\u4e2d\u5fc3\u306b. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092015\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c21\u5dfb2\u53f7 Page80(2015.12)<\/p>\n\n\n\n

\u83c5\u539f \u7531\u7f8e\u5b50, \u795e\u90e8 \u82b3\u5247, \u7b39\u91ce \u9ad8\u55e3, \u8349\u9593 \u5e79\u592b, \u68ee \u826f\u4e4b, \u5317\u5ddd \u5584\u653f, \u9ad8\u6a4b \u54f2, \u6749\u5c71 \u82b3\u6a39, \u798f\u7530 \u96c5\u5e78, \u5ddd\u53c8 \u5747, \u690d\u91ce \u9ad8\u7ae0, \u67f4\u7530 \u654f\u4e4b, \u5cb8\u672c \u88d5\u5145, \u98ef\u7530 \u5f81\u4e8c, \u4e2d\u6751 \u5178\u53f2, \u6749\u6d66 \u525b\uff1a\u53e3\u8154\u6241\u5e73\u82d4\u766c\u6cbb\u7642\u306b\u304a\u3051\u308b\u30bb\u30d5\u30a1\u30e9\u30f3\u30c1\u30f3\u6295\u4e0e\u4f8b\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u52b9\u679c\u304a\u3088\u3073\u6709\u5bb3\u4e8b\u8c61\u306e\u591a\u65bd\u8a2d\u30fb\u5f8c\u65b9\u8996\u7684\u5171\u540c\u7814\u7a76. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092015\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c21\u5dfb2\u53f7 Page87-88(2015.12)<\/p>\n\n\n\n

\u68ee\u672c \u771f\u5f18, \u6d45\u9999 \u5353\u54c9, \u938c\u53e3 \u771f\u7531\u7f8e, \u5c71\u4e0b \u6620\u7f8e, \u5927\u5185 \u5b66, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053\u5927\u5b66\u53e3\u8154\u8a3a\u65ad\u5185\u79d1\u306b\u304a\u3051\u308b\u638c\u8e60\u81bf\u75b1\u75c7\u60a3\u8005\u306e\u81e8\u5e8a\u7d71\u8a08\u5b66\u7684\u691c\u8a0e. \u7b2c25\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092015\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c21\u5dfb2\u53f7 Page82(2015.12)<\/p>\n\n\n\n

Sato J, Kitagawa Y, Watanabe S, Asaka T, Ohga N, Miyakoshi M, Hata H, Okamoto S, Shiga T, Shindoh M, Tamaki N : FMISO-PET reflects not only hypoxia but also cell proliferation in oral squamous cell carcinoma. The 22th International Conference of Oral and Maxillofacial Surgery 2015 (Melbourne), 2015.10<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u4e95\u4e0a \u8fb2\u592b\u7537, \u8c37\u6751 \u6676\u5e83, \u6751\u4e95 \u77e5\u4f73, \u5317\u5ddd \u5584\u653f\uff1a\u30aa\u30db\u30fc\u30c4\u30af\u570f\u306b\u304a\u3051\u308b\u984e\u77ef\u6b63\u624b\u8853\u306e\u73fe\u72b6. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6d45\u9999 \u96c4\u4e00\u90ce\uff1a\u4e21\u5074\u306b\u767a\u751f\u3057\u305f\u9f3b\u6b6f\u69fd\u56a2\u80de\u306e1\u4f8b. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u6df3, \u6749\u6d66 \u5343\u5c0b, \u5c0f\u6797 \u6df3\u4e00, \u7af9\u5ddd \u653f\u7bc4, \u5927\u576a \u8aa0\u6cbb, \u698a\u539f \u5178\u5e78, \u9ce5\u8c37\u90e8 \u7d14\u884c, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053HIV\/AIDS\u6b6f\u79d1\u533b\u7642\u30cd\u30c3\u30c8\u30ef\uff0d\u30af\u69cb\u7bc9\u4e8b\u696d\u306e\u6982\u8981 Profile of the Hokkaido HIV\/AIDS dental medicine network. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u5143\u5ddd \u8ce2\u4e00\u6717, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u81ea\u7acb\u524d\u671f\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b\u56a5\u4e0b\u969c\u5bb3\u3068\u53e3\u8154\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u8abf\u67fb. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u660e, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u85ac\u5264\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u4e88\u9632\u306b\u5bfe\u3059\u308b\u591a\u8840\u5c0f\u677f\u30d5\u30a3\u30d6\u30ea\u30f3\uff08PRF\uff09\u306e\u52b9\u679c\u306b\u95a2\u3059\u308b\u7814\u7a76. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u7267\u91ce \u4fee\u6cbb\u90ce, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u548c\u7530 \u9ebb\u53cb\u7f8e\uff1a\u53e3\u8154\u518d\u5efa\u624b\u8853\u306b\u304a\u3051\u308b\u4e88\u9632\u7684\u6297\u83cc\u85ac\u6295\u4e0e\uff0d\u8853\u5f8c\u7d4c\u904e, \u5728\u9662\u65e5\u6570\u306b\u95a2\u3059\u308b\u691c\u8a0e\uff0d. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708 \u6284\u9332P183<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u4f50\u85e4 \u5065\u5f66\uff1a\u4e0b\u984e\u9aa8\u5468\u56f2\u81bf\u760d\u306b\u7d9a\u767a\u3057\u305f\u4eee\u6027\u52d5\u8108\u7624\u306e1\u4f8b. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708 \u6284\u9332P221<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u4f50\u85e4 \u660e, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u524d\u6b6f\u90e8\u3078\u306e\u8853\u4e2d\u64ad\u7a2e\u304c\u7591\u308f\u308c\u305f\u820c\u764c\u306e1\u4f8b. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u53e4\u5ddd \u5eb7\u5e73, \u6749\u5c71 \u6b63\u535a, \u6bd4\u5609 \u76db\u654f, \u767e\u5408\u8349 \u5065\u572d\u5fd7\uff1a\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u88fd\u5264\u6295\u4e0e\u4e2d\u306b\u304a\u3051\u308b\u629c\u6b6f\u75c7\u4f8b38\u4f8b\u306e\u691c\u8a0e. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u7db2\u585a \u61b2\u751f, \u5317\u5ddd \u7fa9\u653f\uff1a\u9aa8\u82bd\u7d30\u80de\u30fb\u9aa8\u7d30\u80de\u306b\u5bfe\u3059\u308b\u30d3\u30b9\u30d5\u30a9\u30b9\u30d5\u30a9\u30cd\u30fc\u30c8\u88fd\u5264\u306e\u5f71\u97ff. \u7b2c60\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u540d\u53e4\u5c4b\uff092015\u5e7410\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c61(supplement)\uff1a152<\/p>\n\n\n\n

Tsuboi K, Hongo H, Hasegawa T, Yamamoto T, Amizuka N : Histochemical assessment on bone tissues in type II diabetic SDT fatty rats. Australian and New Zealand bone and mineral society (ANZBMS) 2015 Joint ANZBMS, MEPSA and MBSANZ, Annual scientific meeting (Hobart), 2015.11 Program & Abstracts P70<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5bae\u8170 \u660c\u660e, \u6d45\u9999 \u5353\u54c9, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053HIV\/AIDS\u6b6f\u79d1\u533b\u7642\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u69cb\u7bc9\u4e8b\u696d\u306e\u6982\u8981. \u7b2c29\u56de\u65e5\u672c\u30a8\u30a4\u30ba\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u7dcf\u4f1a\uff08\u5927\u962a\u5e02\uff092015\u5e7411\u6708 \u65e5\u672c\u30a8\u30a4\u30ba\u5b66\u4f1a\u8a8c17\u5dfb4\u53f7 Page461(2015.11)<\/p>\n\n\n\n

\u4e09\u6cb3 \u6d0b\u5e73\uff1amRNA\u306e\u5b89\u5b9a\u5316\u30b7\u30b9\u30c6\u30e0\u3092\u5229\u7528\u3057\u305f\u816b\u760d\u6eb6\u89e3\u30a2\u30c7\u30ce\u30a6\u30a4\u30eb\u30b9\u306e\u958b\u767a. \u5e73\u621027\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092015\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c36\u5dfb2\u53f7 Page162(2016.03)<\/p>\n\n\n\n

\u64ad\u78e8 \u7f8e\u6a39\uff1a\u5b64\u675f\u6838\u304a\u3088\u3073\u6700\u5f8c\u91ce\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u6d3b\u52d5\u306b\u5bfe\u3059\u308b\u8840\u7cd6\u5024\u4e0a\u6607\u306e\u5f71\u97ff. \u5e73\u621027\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092015\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c36\u5dfb2\u53f7 Page166(2016.03)<\/p>\n\n\n\n

\u4e2d\u6751 \u88d5\u4ecb\uff1a\u6297RANKL\u4e2d\u548c\u6297\u4f53\u304c\u95a2\u4e0e\u3057\u305f\u984e\u9aa8\u58ca\u6b7b\u306f\u514d\u75ab\u5fdc\u7b54\u306e\u4e0d\u5747\u8861\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b. \u5e73\u621027\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092015\u5e7411\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c36\u5dfb2\u53f7 Page167(2016.03)<\/p>\n\n\n\n

\u5e73\u621028\u5e74\uff082016\u5e74\uff09<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u6d45\u9999 \u5353\u54c9, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u9ed2\u5d8b \u96c4\u5fd7, \u5317\u6751 \u54f2\u4e5f, \u6797 \u5229\u5f66, \u7b95\u8f2a \u548c\u884c, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u3073\u307e\u3093\u6027\u786c\u5316\u6027\u9aa8\u9ac4\u708e\u3068\u306e\u9451\u5225\u304c\u56f0\u96e3\u3067\u3042\u3063\u305f\u984e\u9aa8\u4e2d\u5fc3\u6027\u764c\u306e1\u4f8b. \u7b2c34\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092016\u5e741\u6708<\/p>\n\n\n\n

Morimoto M, Ohga N, Yamazaki Y, Sato J, Asaka T, Hata H, Satoh C, Kitagawa Y : Elimination of oral candidiasis may increase stimulated whole salivary flow rate. 2016 Annual Congress of ROC Association of Oral and Maxillofacial Surgeons (Taiwan), 2016.3<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f: \u8edf\u9aa8\u5185\u9aa8\u5316\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u5fae\u7d30\u69cb\u9020\u5b66\u7684\u691c\u7d22\uff0e \u7b2c121\u56de\u65e5\u672c\u89e3\u5256\u5b66\u4f1a\u7dcf\u4f1a\u5168\u56fd\u5b66\u8853\u96c6\u4f1a\u3000\uff08\u90e1\u5c71\uff092016\u5e743\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6\uff1a133(2016.03)<\/p>\n\n\n\n

Asaka T, Ohga N, Sato J, Satoh C, Kitagawa Y : Evaluation of platelet-rich fibrin on prevention of MRONJ. American Academy of Oral Medicine Annual Meeting (Atlanta),\u30002016.4<\/p>\n\n\n\n

Tsuboi K, Amizuka N, Kitagawa Y : Histochemical examination on the effects of alendronate on osteocytic lacunar-canalicular system. American Academy of Oral Medicine Annual Meeting (Atlanta),\u30002016.4<\/p>\n\n\n\n

\u6e05\u6c34 \u516d\u82b1, \u7530\u4e2d \u7f8e\u548c, \u5c71\u5d0e \u3086\u304b\u308a, \u672c\u76ee \u307f\u305a\u304d, \u4e2d\u6751 \u5353\u90ce\uff1a\u30e6\u30fc\u30a4\u30f3\u30b0\u8089\u816b\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305fEWS\u2010FLI1\u306e\u6a5f\u80fd\u89e3\u6790. \u7b2c105\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u7dcf\u4f1a (\u4ed9\u53f0) 2016\u5e744\u6708 \u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u4f1a\u8a8c105\u5dfb\uff11\u53f7 Page541(2016.04)<\/p>\n\n\n\n

\u5317\u5ddd \u5584\u653f\uff1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e04 \u85ac\u5264\u95a2\u9023\u6027\u984e\u9aa8\u58ca\u6b7b(MRONJ)\u306e\u6700\u65b0\u77e5\u898b\u3092\u79d1\u5b66\u3059\u308b MRONJ\u306b\u5bfe\u3059\u308b\u9ad8\u6c17\u5727\u9178\u7d20\u7642\u6cd5(HBO)\u306e\u5fdc\u7528\u3068FDG-PET\u306b\u3088\u308b\u8a55\u4fa1. \u7b2c70\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092016\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c65\u5dfb2\u53f7 Page100(2016.07)<\/p>\n\n\n\n

\u938c\u53e3 \u771f\u7531\u7f8e, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053\u5927\u5b66\u53e3\u8154\u8a3a\u65ad\u5185\u79d1\u306b\u304a\u3051\u308b\u985e\u5929\u75b1\u7621\u306e\u81e8\u5e8a\u7d71\u8a08\u5b66\u7684\u691c\u8a0e. \u7b2c70\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092016\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c65\u5dfb2\u53f7 Page192(2016.07)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u52a0\u5cf6 \u88d5\u57fa, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u68ee\u672c \u771f\u5f18, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u306b\u3088\u308b\u553e\u6db2\u4e2d\u306e\u514d\u75ab\u7d30\u80de\u89e3\u6790. \u7b2c70\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u535a\u591a\uff092016\u5e744\u6708 \u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u96d1\u8a8c65\u5dfb2\u53f7 Page193(2016.07)<\/p>\n\n\n\n

\u5927\u5185 \u5b66\uff1a\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u306b\u304a\u3051\u308bTLRs\u306e\u767a\u73fe\u30fb\u6a5f\u80fd\u306a\u3089\u3073\u306bNK\u6d3b\u6027\u306b\u3064\u3044\u3066. \u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092016\u5e745\u6708 \u5317\u6d77\u9053\u6b6f\u5b66\u96d1\u8a8c (0914-7063)37\u5dfb1\u53f7 Page54(2016.09)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6d45\u9999 \u96c4\u4e00\u90ce\uff1a\u5de6\u9854\u9762\u58ca\u6b7b\u6027\u7b4b\u819c\u708e\u306e1\u4f8b. \u7b2c54\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u5c71\u5f62\uff092016\u5e746\u6708<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u7d4c\u53e3Bisphosphonate\u304c\u594f\u529f\u3057\u305fSAPHO\u75c7\u5019\u7fa4\u306e1\u4f8b. \u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u5c71\u5f62\uff092016\u5e746\u6708 \u6284\u9332P30(2016.06)<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u75c7\u4f8b\u306e\u691c\u8a0e. \u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u5c71\u5f62\uff092016\u5e746\u6708 \u6284\u9332P41(2016.6)<\/p>\n\n\n\n

\u52a0\u85e4 \u6cf0\u53f2, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u9ed2\u5d8b \u96c4\u5fd7, \u938c\u53e3 \u771f\u7531\u7f8e, \u5317\u6751 \u54f2\u4e5f, \u7b95\u8f2a \u548c\u884c, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u4e0a\u984e\u306bMTX-LPD\u3068MRONJ\u304c\u4f75\u767a\u3057\u305f1\u4f8b. \u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u5c71\u5f62\uff092016\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c \u7b2c62\u5dfb \u7b2c10\u53f7 P545<\/p>\n\n\n\n

\u6749\u5c71 \u5b5d\u535a, \u4f50\u85e4 \u6df3, \u4e09\u6cb3 \u6d0b\u5e73, \u5927\u5185 \u5b66, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5178\u5b5d, \u4f50\u85e4 \u5343\u6674, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u820c\u306b\u751f\u3058\u305f\u9846\u7c92\u7d30\u80de\u816b\u306e\u4e00\u4f8b. \u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u5c71\u5f62\uff092016\u5e746\u6708 \u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u96d1\u8a8c62\u5dfb10\u53f7Page544-549(2016.12)<\/p>\n\n\n\n

\u6749\u5c71 \u6b63\u535a, \u53e4\u5ddd \u5eb7\u5e73, \u6bd4\u5609 \u76db\u654f, \u6728\u8c37 \u5353\u53f2, \u9577\u5ca1 \u771f\u4eba, \u98ef\u7530 \u5584\u5e78, \u4e0a\u689d \u670b\u4e4b, \u9b3c\u585a \u54f2\u90ce, \u767e\u5408\u8349 \u5065\u572d\u5fd7\uff1a\u982d\u9838\u90e8\u764c\u8853\u5f8c\u5408\u4f75\u75c7\u306b\u5bfe\u3059\u308b\u8853\u524d\u53e3\u8154\u885b\u751f\u72b6\u614b\u8a55\u4fa1\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1. \u7b2c40\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5927\u5bae\uff092016\u5e746\u6708 \u982d\u9838\u90e8\u764c\u5b66\u4f1a\u96d1\u8a8c42\u5dfb2\u53f7Page203(2016.05)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u9ed2\u5d8b \u96c4\u5fd7, \u52a0\u85e4 \u6cf0\u53f2, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u53e3\u5e95\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c40\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5927\u5bae\uff092016\u5e746\u6708 \u982d\u9838\u90e8\u764c42\u5dfb2\u53f7 Page232(2016.05)<\/p>\n\n\n\n

\u5409\u5ddd \u548c\u4eba, \u79e6 \u6d69\u4fe1, \u5bae\u8170 \u660c\u660e, \u9ed2\u5d8b \u96c4\u5fd7, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u4e0b\u984e\u6b6f\u8089\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u6cbb\u7642\u6210\u7e3e. \u7b2c40\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5927\u5bae\uff092016\u5e746\u6708 \u982d\u9838\u90e8\u764c42\u5dfb2\u53f7 Page179(2016.05)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u8349\u6df1 \u516c\u79c0, \u9b3c\u585a \u54f2\u90ce, \u4e0a\u689d \u670b\u4e4b, \u98ef\u7530 \u5584\u5e78, \u767e\u5408\u8349 \u5065\u572d\u5fd7\uff1a\u820c\u6241\u5e73\u4e0a\u76ae\u764cstage II\u75c7\u4f8b\u306b\u304a\u3051\u308b\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u691c\u8a0e. \u7b2c40\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u5927\u5bae\uff092016\u5e746\u6708 \u982d\u9838\u90e8\u764c42\u5dfb2\u53f7 Page196(2016.05)<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u8edf\u9aa8\u5185\u9aa8\u5316\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u3068perivascular cell(septoclast)\u306e\u7d44\u7e54\u5316\u5b66\u30fb\u5fae\u7d30\u69cb\u9020\u5b66\u7684\u691c\u7d22. \u7b2c36\u56de \u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\uff08\u65b0\u6f5f\uff092016\u5e746\u6708 \u65e5\u672c\u9aa8\u5f62\u614b\u8a08\u6e2c\u5b66\u4f1a\u96d1\u8a8c26\u5dfb1\u53f7 Page S123 (2016.06)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u672c\u90f7 \u88d5\u7f8e, \u9577\u8c37\u5ddd \u667a\u9999, \u5317\u5ddd \u5584\u653f, \u7db2\u585a \u61b2\u751f\uff1a\u80a5\u6e802\u578b\u7cd6\u5c3f\u75c5\u30e2\u30c7\u30ebSDTfatty\u30e9\u30c3\u30c8\u306b\u304a\u3051\u308b\u9aa8\u306e\u5fae\u7d30\u69cb\u9020\u5b66\u7684\u89e3\u6790\uff0e \u7b2c2\u56de\u65e5\u672c\u9aa8\u514d\u75ab\u5b66\u4f1a\uff08\u6c96\u7e04\uff092016\u5e747\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6\uff1a107<\/p>\n\n\n\n

\u571f\u5c4b \u6075\u674e\u4f73, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u5b87\u7530\u5ddd \u4fe1\u4e4b, \u7db2\u585a \u61b2\u751f\uff1a\u8edf\u9aa8\u5185\u9aa8\u5316\u306b\u304a\u3051\u308b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u3068perivascular cell\u306e\u7d30\u80de\u9593\u9023\u643a\u306b\u95a2\u3059\u308b\u7d44\u7e54\u5316\u5b66\u7684\u691c\u7d22\uff0e\u7b2c34\u56de\u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092016\u5e747\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6\uff1a186 (2016.07)<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u672c\u90f7 \u88d5\u7f8e, \u5c71\u672c \u77e5\u771f\u4e5f, \u9577\u8c37\u5ddd \u667a\u9999, \u7db2\u585a \u61b2\u751f\uff1a\u65b0\u898f\u80a5\u6e80\uff12\u578b\u7cd6\u5c3f\u75c5\u30e2\u30c7\u30ebSDT fatty\u30e9\u30c3\u30c8\u306e\u9aa8\u7d44\u7e54\u306e\u7d44\u7e54\u5316\u5b66\u7684\u5909\u5316\u306b\u3064\u3044\u3066\uff0e\u7b2c34\u56de\u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5927\u962a\uff092016\u5e747\u6708 \u65e5\u672c\u9aa8\u4ee3\u8b1d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u30d7\u30ed\u30b0\u30e9\u30e0\u6284\u9332\u96c634\u56de Page218(2016.07)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3\uff1a\u898b\u9003\u3057\u3066\u306f\u306a\u3089\u306a\u3044\u984e\u95a2\u7bc0\u75c7\u306b\u985e\u4f3c\u3057\u305f\u75c7\u72b6\u3092\u6765\u3059\u75be\u60a3 (Case 1)\u958b\u53e3\u969c\u5bb3\u304a\u3088\u3073\u6442\u98df\u969c\u5bb3\u304b\u3089\u984e\u95a2\u7bc0\u75c7\u304c\u7591\u308f\u308c\u305f1\u4f8b. \u7b2c29\u56de\u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\u30fb\u6559\u80b2\u30bb\u30df\u30ca\uff0d\u300c\u898b\u9003\u3057\u3066\u306f\u306a\u3089\u306a\u3044\u984e\u95a2\u7bc0\u75c7\u306b\u985e\u4f3c\u3057\u305f\u75c7\u72b6\u3092\u6765\u3059\u75be\u60a3\u300d\uff08\u7bb1\u6839\uff092016\u5e747\u6708 \u65e5\u672c\u984e\u95a2\u7bc0\u5b66\u4f1a\u96d1\u8a8c28\u5dfbSuppl. Page75(2016.07)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6d45\u9999 \u96c4\u4e00\u90ce\uff1a\u5168\u8eab\u9ebb\u9154\u4e0d\u80fd\u3068\u3055\u308c\u305f\u4e0b\u984e\u9aa8\u9aa8\u6298\u306e1\u4f8b. \u7b2c18\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092016\u5e747\u6708<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u5927\u8cc0 \u5247\u5b5d, \u4eca\u5f85 \u8ce2\u6cbb, \u5409\u5ddd \u548c\u4eba, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u89d2\u5316\u56a2\u80de\u6027\u6b6f\u539f\u6027\u816b\u760d\u6458\u51fa\u8853\u5f8c\u3001\u75c5\u7684\u9aa8\u6298\u90e8\u4f4d\u306b\u7570\u5e38\u9aa8\u5438\u53ce\u3092\u8a8d\u3081\u305f1\u4f8b. \u7b2c18\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u6771\u4eac\uff092016\u5e747\u6708 \u53e3\u8154\u984e\u9854\u9762\u5916\u50b715\u5dfb1-2\u53f7 Page71(2016.12)<\/p>\n\n\n\n

Tsuchiya E, Hasegawa T, Hongo H, Yamamoto T, Kitagawa Y, Amizuka N : Histochemical assessment for vascular endothelial cells and perivascular cells during endochondral ossification. The Joint Annual Scientific Meetings of the Endocrine Society of Australia, the Society for Reproductive Biology and the Australian and New Zealand Bone and Mineral Society (ESA\/SRB\/ANZBMS Joint meeting 2016) (Gold Coast), 2016.8<\/p>\n\n\n\n

\u4e80\u5d0e \u826f\u52a9, \u4f50\u4f2f \u6b69, \u9577\u8c37\u90e8 \u6643, \u5317\u5ddd \u5584\u653f, \u9234\u6728 \u654f\u5f66, \u67f4\u7530 \u5065\u4e00\u90ce\uff1aAggregatibacter actinomycetemcomitans DNA\u306b\u3088\u308b\u30a4\u30f3\u30d5\u30e9\u30de\u30bd\u30fc\u30e0\u306e\u6d3b\u6027\u5316. \u7b2c58\u56de\u6b6f\u79d1\u57fa\u790e\u533b\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092016\u5e748\u6708 Journal of Oral Biosciences Supplement2016\u5dfb Page374(2016.09)<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5408\u540c\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff11\u300cMedically unexplained oral symptom\u3078\u306e\u53e3\u8154\u5185\u79d1\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u300d \u5f53\u79d1\u306b\u304a\u3051\u308b\u300cMedically unexplained oral symptom\u300d\u60a3\u8005\u3078\u306e\u5bfe\u5fdc. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c29\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u5ca1\u5c71\u5e02\uff092016\u5e749\u6708 \u6284\u9332P48 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page113(2016.12)<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u68ee\u672c \u660c\u5f18, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u30c7\u30ce\u30b9\u30de\u30d6\u4f11\u85ac\u306b\u3088\u308a\u8150\u9aa8\u5206\u96e2\u30fb\u4e0a\u76ae\u5316\u306b\u81f3\u3063\u305fMRONJ\u306e1\u4f8b. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c29\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u5ca1\u5c71\uff092016\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page118(2016.12), \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c30\u5dfb1\u53f7 Page102(2017.02)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5185\u306b\u521d\u767a\u75c7\u72b6\u3092\u5448\u3057\u305f\u6025\u6027\u524d\u9aa8\u9ac4\u7403\u6027\u767d\u8840\u75c5\u306e1\u4f8b. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c29\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u5ca1\u5c71\uff092016\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page123(2016.12), \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c30\u5dfb1\u53f7 Page107(2017.02)<\/p>\n\n\n\n

\u677e\u4e0b \u8cb4\u60e0, \u5143\u5ddd \u8ce2\u4e00\u90ce, \u5ca1\u7530 \u548c\u9686, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f, \u5c71\u5d0e \u88d5\uff1a\u5730\u57df\u81ea\u7acb\u9ad8\u9f62\u8005\u306e\u5473\u899a\u7570\u5e38\u3068\u54ac\u5408\u72b6\u614b\u306e\u95a2\u9023\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c29\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u5ca1\u5c71\uff092016\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page125-126(2016.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c30\u5dfb1\u53f7 Page109-110(2017.02)<\/p>\n\n\n\n

\u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u6df3, \u5c71\u4e0b \u6620\u7f8e, \u5927\u8cc0 \u5247\u5b5d, \u5317\u6751 \u54f2\u4e5f, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u5fc3\u79fb\u690d\u60a3\u8005\u306b\u767a\u75c7\u3057\u305f\u30a8\u30d9\u30ed\u30ea\u30e0\u30b9\u306b\u8d77\u56e0\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u96e3\u6cbb\u6027\u53e3\u5185\u708e\u306e1\u4f8b. \u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c29\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u5ca1\u5c71\uff092016\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page157(2016.12)\uff0c\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c30\u5dfb1\u53f7 Page141(2017.02)<\/p>\n\n\n\n

\u5143\u5ddd \u8ce2\u4e00\u6717, \u4f50\u85e4 \u660e, \u5927\u8cc0 \u5247\u5b5d, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u81ea\u7acb\u524d\u671f\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u5473\u899a\u7570\u5e38\u306b\u95a2\u3059\u308b\u75ab\u5b66\u7814\u7a76.\u7b2c26\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c29\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u5ca1\u5c71\uff092016\u5e749\u6708 \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c22\u5dfb2\u53f7 Page165(2016.12) \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u96d1\u8a8c30\u5dfb1\u53f7 Page149(2017.02)<\/p>\n\n\n\n

Sato J, Kitagawa Y, Watanabe S, Hirata K, Okamoto S, Ohga N, Asaka T, Miyakoshi M, Hata H, Shiga T, Shindoh M, Nagara T : Relationships between FMISO- and FDG-PET parameters including hypoxic volume of the tumor and prognosis in patients with oral squamous cell carcinoma after surgery. Annual Congress of the European Association of Nuclear Medicine 2016 (Barcelona), 2016.10 Abstract P56<\/p>\n\n\n\n

Miyakoshi M : ORN: Osteoradionecrosis of Jaws ?Prevention, Treatment at Hokkaido University Hospital-. The Meeting of the 25th Anniversary Celebration of Sister School Affiliation between Graduate School of Dental Medicine, Hokkaido University and School of Dentistry, Chonbuk National University (Jeonju), 2016.10 Abstract P15<\/p>\n\n\n\n

\u6e05\u6c34 \u516d\u82b1, \u7530\u4e2d \u7f8e\u548c, \u5c71\u5d0e \u3086\u304b\u308a, \u672c\u76ee \u307f\u305a\u304d, \u5317\u5ddd \u5584\u653f, \u4e2d\u6751 \u5353\u90ce\uff1a\u9aa8\u8edf\u90e8\u816b\u760d\u306e\u878d\u5408\u907a\u4f1d\u5b50\u306b\u3088\u308b\u907a\u4f1d\u5b50\u5236\u5fa1\u6a5f\u69cb. \u7b2c75\u56de\u65e5\u672c\u764c\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092016\u5e7410\u6708 \u65e5\u672c\u764c\u5b66\u4f1a\u7dcf\u4f1a\u8a18\u4e8b75\u56de Page P-3030(2016.10)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u5409\u5ddd \u548c\u4eba, \u5bae\u8170 \u660c\u660e, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u4e0b\u984e\u9aa8\u653e\u5c04\u7dda\u6027\u9aa8\u58ca\u6b7b 13 \u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708<\/p>\n\n\n\n

Fatema CN, Kuroshima T, Asaka T, Abe T, Sato J, Tamaki N, Kitagawa Y:Usefulness of MET-PET in oral cancer. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708<\/p>\n\n\n\n

\u68ee\u672c \u771f\u5f18, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u540c\u6642\u306b3\u672c\u306e\u667a\u6b6f\u629c\u6b6f\u3092\u884c\u3063\u305fvon Willebrand\u75c5\u306e1\u4f8b. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708<\/p>\n\n\n\n

\u4e2d\u6751 \u88d5\u4ecb, \u6749\u5c71 \u5b5d\u535a, \u5317\u5ddd \u5584\u653f\uff1a\u6297RANKL\u4e2d\u548c\u6297\u4f53\u88fd\u5264\u95a2\u9023\u6027\u984e\u9aa8\u58ca\u6b7b\u306f\u514d\u75ab\u5fdc\u7b54\u306e\u4e0d\u5747\u8861\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708 \u6284\u9332\uff1a191<\/p>\n\n\n\n

\u592a\u5b50 \u82b3\u4ec1\uff0c\u6c34\u8d8a \u5b5d\u5178\uff0c\u5357\u689d \u6c99\u8036\u52a0\uff0c\u6238\u585a \u9756\u5247\uff0c\u5317\u5ddd \u5584\u653f\uff1a\u4e73\u764c\u9aa8\u8ee2\u79fb\u75c7\u4f8b\u306b\u304a\u3051\u308b\u85ac\u5264\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e\uff0e\u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u30fb\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3. \u30df\u30cb\u30ec\u30af\u30c1\u30e3\uff0d3\uff1b\u82e5\u624b\u7814\u7a76\u8005\u306b\u4f1d\u3048\u305f\u3044\u82f1\u8a9e\u81e8\u5e8a\u8ad6\u6587\u306e\u66f8\u304d\u65b9. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708 \u6284\u9332P46<\/p>\n\n\n\n

\u4f50\u85e4 \u6df3, \u5927\u8cc0 \u5247\u5b5d, \u6d45\u9999 \u5353\u54c9, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u4f4e\u9178\u7d20\u5bb9\u7a4d; hypoxic volume \u306f\u8853\u5f8c\u306e\u4e88\u5f8c\u4e88\u6e2c\u56e0\u5b50\u306b\u306a\u308a\u3048\u308b. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708 \u6284\u9332P251<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u9ad8\u91ce \u660c\u58eb, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u5728\u5b85\u7de9\u548c\u30b1\u30a2\u3092\u5b9f\u65bd\u3057\u305f\u53e3\u8154\u764c\u306e2\u4f8b.\u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708 \u6284\u9332P332<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u5f53\u79d1\u3067\u7d4c\u9a13\u3057\u305f\u30c7\u30ce\u30b9\u30de\u30d6\u6295\u4e0e\u60a3\u8005\u306e\u85ac\u5264\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\uff08MRONJ\uff09\u306e\u691c\u8a0e. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708 \u6284\u9332P159<\/p>\n\n\n\n

Asaka T, Sato J, Fatema CN, Hata H, Miyakoshi M, Satoh A, Kitagawa Y\uff1aNew quantitative evaluation for osteomyelitis of the jaw by Metabolic activity. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u8fbb \u5b66, \u5317\u5ddd \u5584\u653f\uff1a\u958b\u8a2d\u304b\u3089\uff11\u5e74\u7d4c\u904e\u3057\u305f\u5317\u898b\u8d64\u5341\u5b57\u75c5\u9662\u6b6f\u79d1\u53e3\u8154\u5916\u79d1\u306e\u73fe\u72b6\u3068\u4eca\u5f8c\u306e\u5c55\u671b. \u7b2c61\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u5e55\u5f35\uff092016\u5e7411\u6708<\/p>\n\n\n\n

\u9234\u6728 \u5cfb\u4e00, \u6709\u99ac \u592a\u90ce, \u5317\u5ddd \u5584\u653f\uff1a\u5065\u5e38\u8005\u306b\u304a\u3051\u308b\u7d99\u7d9a\u3057\u305f\u7b4b\u53ce\u7e2e\u306b\u3088\u308b\u54ac\u7b4b\u5185\u306e\u8840\u6db2\u9178\u7d20\u52d5\u614b\u5065\u5e38\u8005\u306b\u304a\u3051\u308b\u7d99\u7d9a\u3057\u305f\u7b4b\u53ce\u7e2e\u306b\u3088\u308b\u54ac\u7b4b\u5185\u306e\u8840\u6db2\u9178\u7d20\u52d5\u614b.(Blood oxygenation of masseter muscle during sustained elevated muscle activity in healthy participants.) \u5e73\u621028\u5e74\u5ea6\u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u79cb\u5b63\u5b66\u8853\u5927\u4f1a (\u672d\u5e4c) 2016\u5e7411\u6708<\/p>\n\n\n\n

\u5e73\u621029\u5e74\uff082017\u5e74\uff09<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u548c\u7530 \u9ebb\u53cb\u7f8e\uff1a\u5f53\u9662\u8a2a\u554f\u6b6f\u79d1\u306e\u5730\u57df\u5305\u62ec\u30b1\u30a2\u30b7\u30b9\u30c6\u30e0\u3078\u306e\u95a2\u308f\u308a-\u53e3\u8154\u764c\u60a3\u8005\u306e\u5728\u5b85\u7de9\u548c\u30b1\u30a2-. \u7b2c26\u56de\u65e5\u672c\u6709\u75c5\u8005\u6b6f\u79d1\u533b\u7642\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u91d1\u6ca2\uff092017\u5e743\u6708<\/p>\n\n\n\n

\u938c\u53e3 \u771f\u7531\u7f8e, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u5185\u306b\u521d\u767a\u75c7\u72b6\u3092\u5448\u3057\u305f\u6c34\u75b1\u6027\u985e\u5929\u75b1\u7621\u306e2\u4f8b. \u7b2c43\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\uff08\u51fd\u9928\uff092017\u5e745\u6708<\/p>\n\n\n\n

\u963f\u90e8 \u8cb4\u6d0b, \u8fbb \u5b66, \u5d8b\u5d0e \u5eb7\u76f8, \u897f\u7530 \u4f73\u7e54, \u85e4\u76db \u771f\u6a39, \u5927\u576a \u8aa0\u6cbb\uff1a\u75c5\u75c5\u9023\u643a\u306b\u3066\u6cbb\u7642\u3092\u884c\u3063\u305f\u81ea\u6bba\u4f01\u56f3\u306b\u3088\u308b\u4e0b\u984e\u9aa8\u9aa8\u6298\u306e1\u4f8b. \u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c43\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u51fd\u9928\uff092017\u5e745\u6708 \u6284\u9332P37<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e\uff1a\u6c34\u75b1\u6027\u985e\u5929\u75b1\u7621\u81ea\u5df1\u6297\u539f17\u578b\u30b3\u30e9\u30fc\u30b2\u30f3\/BP180\u306e\u7570\u306a\u308b\u30a8\u30d4\u30c8\u30fc\u30d7\u306b\u5bfe\u3059\u308b\u6297\u4f53\u306e\u75c5\u539f\u6027\u89e3\u6790. \u5317\u6d77\u9053\u6b6f\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\u6b6f\u5b66\u4f1a\u8cde\u53d7\u8cde\u8005\u8b1b\u6f14\uff08\u672d\u5e4c\uff092017\u5e745\u6708 \u6284\u9332P4(2017.05)<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u814e\u764c\u591a\u767a\u9aa8\u8ee2\u79fb\u60a3\u8005\u306b\u898b\u3089\u308c\u305f\u85ac\u5264\u95a2\u9023\u984e\u9aa8\u58ca\u6b7b\u306e1\u4f8b. \u7b2c41\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u4eac\u90fd\uff092017\u5e746\u6708 \u982d\u9838\u90e8\u764c 43\u5dfb2\u53f7 Page249(2017.05)<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u306e\u9838\u90e8\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u75c7\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c35\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092017\u5e741\u6708<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u85e4 \u660e, \u9ed2\u5d8b \u96c4\u5fd7, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u53e3\u8154\u764c\u624b\u8853\u75c7\u4f8b\u306e\u8853\u5f8c\u305b\u3093\u5984\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c35\u56de\u65e5\u672c\u53e3\u8154\u816b\u760d\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u535a\u591a\uff092017\u5e741\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u96c6\uff1a37<\/p>\n\n\n\n

Mikawa Y, Kitamura T, Yanagawa A, Kitagaawa Y, Sindo M, Higasino F : Conditionally replicative adenovirus controlled by the stabilization system of AU-rich elements containing mRNA. 30th Annual conference of TAOMS (Taipei), 2017.3<\/p>\n\n\n\n

Kamaguchi M, Asaka T, Yamashita E, Wada M, Ohga N, Satoh C, Sato J, Kitamura T, Shindoh M, Kitagawa Y : Clinical study for diagnosis and treatment of bullous pemphigoid and mucous membrane pemphigoid. 30th Annual conference of TAOMS (Taipei), 2017.3<\/p>\n\n\n\n

Tsuchiya E, Hasegawa T, Amizuka N, Kitagawa Y\uff1a\u3000Histochemical assessment for vascular endothelial cells and perivascular cells during endochondral ossification. American Academy of Oral Medicine Annual Meeting ( Orlando), 2017.4<\/p>\n\n\n\n

\u6e05\u6c34 \u516d\u82b1, \u7530\u4e2d \u7f8e\u548c, \u5c71\u5d0e \u3086\u304b\u308a, \u672c\u76ee \u307f\u305a\u304d, \u5317\u5ddd \u5584\u653f, \u4e2d\u6751 \u5353\u90ce\uff1a\u30e6\u30fc\u30a4\u30f3\u30b0\u8089\u816b\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u878d\u5408\u907a\u4f1d\u5b50EWS-FLI1\u306e\u6a5f\u80fd\u89e3\u6790. \u7b2c106\u56de\u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u7dcf\u4f1a\uff08\u6771\u4eac\uff092017\u5e744\u6708 \u65e5\u672c\u75c5\u7406\u5b66\u4f1a\u4f1a\u8a8c106\u5dfb1\u53f7 Page297(2017.03)<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5409\u5ddd \u548c\u4eba, \u4eca\u5f85 \u8ce2\u6cbb, \u938c\u53e3 \u771f\u7531\u7f8e, \u6797 \u4fe1, \u4e0a\u7530 \u502b\u5f18\uff1a\u304c\u3093\u60a3\u8005\u306eARONJ\u306b\u5bfe\u3059\u308b\u4f11\u85ac\u306e\u610f\u7fa9\u3068\u30ea\u30b9\u30af\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c71\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u611b\u5a9b\uff092017\u5e744\u6708 \u6284\u9332P158<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u4eca\u5f85 \u8ce2\u6cbb, \u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u6df3, \u5317\u5ddd \u5584\u653f\uff1a\u9aa8\u9ac4\u708e\u306e\u65b0\u305f\u306a\u8a55\u4fa1\u65b9\u6cd5\u3068\u3057\u3066\u306e\u9aa8SPECT\u5b9a\u91cf\u89e3\u6790\u30bd\u30d5\u30c8GI-BONE\u306e\u6709\u7528\u6027. \u7b2c71\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u611b\u5a9b\uff092017\u5e744\u6708 \u6284\u9332P201<\/p>\n\n\n\n

\u5bae\u8170 \u660c\u660e, \u5409\u5ddd \u548c\u4eba, \u6e05\u6c34 \u516d\u82b1, \u938c\u53e3 \u771f\u7531\u7f8e, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u984e\u4e0b\u30ea\u30f3\u30d1\u7bc0\u306b\u307f\u3089\u308c\u305fIgG4\u95a2\u9023\u30ea\u30f3\u30d1\u7bc0\u75c7\u306e1\u4f8b. \u7b2c71\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u611b\u5a9b\uff092017\u5e744\u6708 \u6284\u9332P235<\/p>\n\n\n\n

\u6d45\u9999\u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u4f50\u85e4 \u5343\u6674, \u5c71\u5d0e \u88d5, \u5317\u5ddd \u5584\u653f\uff1a\u591a\u8840\u5c0f\u677f\u30d5\u30a3\u30d6\u30ea\u30f3\u306f\u7d4c\u53e3\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u88fd\u5264\u5185\u670d\u60a3\u8005\u306e\u629c\u6b6f\u7aa9\u6cbb\u7652\u4fc3\u9032\u306b\u5bc4\u4e0e\u3059\u308b. \u7b2c71\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u611b\u5a9b\uff092017\u5e744\u6708 \u6284\u9332P248<\/p>\n\n\n\n

\u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u5bae\u8170 \u660c\u660e, \u4f50\u85e4 \u5343\u6674, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u764c\u306eFMISO-PET\u3067\u63cf\u51fa\u3055\u308c\u305f\u4f4e\u9178\u7d20\u9818\u57df\u3068\u816b\u760d\u8840\u7ba1\u5bc6\u5ea6\uff08MVD\uff09\u3068\u306e\u95a2\u4fc2. \u7b2c71\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u611b\u5a9b\uff092017\u5e744\u6708 \u6284\u9332P258<\/p>\n\n\n\n

\u67f3\u8c37 \u7f8e\u6c99,\u9593\u77f3 \u5948\u6e56, \u9ce5\u5c45 \u3061\u3055\u307b, \u5927\u8cc0 \u5247\u5b5d, \u912d \u6f22\u5fe0, \u9032\u85e4 \u6b63\u4fe1, \u5317\u5ddd \u5584\u653f, \u6a0b\u7530 \u4eac\u5b50\uff1a\u53e3\u8154\u504f\u4e0a\u76ae\u764c\u306b\u304a\u3051\u308b\u816b\u760d\u8840\u7ba1\u30de\u30fc\u30ab\u30fcCXCR7\u306e\u767a\u73fe\u3068\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u56e0\u5b50\u3068\u306e\u6bd4\u8f03\u89e3\u6790. \u7b2c71\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u611b\u5a9b\uff092017\u5e744\u6708 \u6284\u9332P287<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c122\u4f8b\u306e\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u691c\u8a0e. \u7b2c43\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u51fd\u9928\uff092017\u5e745\u6708<\/p>\n\n\n\n

\u7af9\u5ddd \u82f1\u8f1d, \u9ed2\u5d8b \u96c4\u5fd7, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u6b6f\u539f\u6027\u75bc\u75db\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u305f\u7fa4\u767a\u982d\u75db\u306e2\u4f8b. \u7b2c43\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u51fd\u9928\uff092017\u5e745\u6708<\/p>\n\n\n\n

\u6e05\u6c34 \u9054\u54c9, \u4f50\u85e4 \u660e, \u5927\u8cc0 \u5247\u5b5d, \u576a\u4e95 \u9999\u5948\u5b50, \u4eca\u5f85 \u8ce2\u6cbb, \u5317\u5ddd \u5584\u653f\uff1a\u8853\u5f8c\u305b\u3093\u5984\u306b\u82e6\u616e\u3057\u305f\u820c\u764c\u306e1\u4f8b. \u7b2c43\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u51fd\u9928\uff092017\u5e745\u6708 \u6284\u9332P16<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6d45\u9999 \u96c4\u4e00\u90ce\uff1a\u539f\u56e0\u4e0d\u660e\u306e\u53f3\u8033\u524d\u90e8\u3001\u53f3\u984e\u4e0b\u90e8\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u3092\u8a8d\u3081\u305f1\u4f8b. \u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u79d1\u5b66\u4f1a\u30fb\u7b2c43\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u51fd\u9928\uff092017\u5e745\u6708<\/p>\n\n\n\n

\u4e2d\u6751 \u88d5\u4ecb, \u4f50\u85e4 \u6df3, \u6d45\u9999 \u5353\u54c9, \u5927\u8cc0 \u5247\u5b5d, \u4f50\u85e4 \u5343\u6674, \u5317\u5ddd \u5584\u653f\uff1a\u5b8c\u5168\u623f\u5ba4\u30d6\u30ed\u30c3\u30af\u60a3\u8005\u306e\u4e0b\u984e\u57cb\u4f0f\u667a\u6b6f\u629c\u6b6f\u306e\uff11\u4f8b. \u7b2c55\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u5317\u65e5\u672c\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u51fd\u9928\uff092017\u5e745\u6708 \u6284\u9332P72<\/p>\n\n\n\n

\u9ed2\u5d8b \u96c4\u5fd7, \u576a\u4e95 \u9999\u5948\u5b50, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c122\u4f8b\u306e\u4e88\u5f8c\u4e0d\u826f\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u75c5\u7406\u5b66\u7684\u691c\u8a0e. \u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u4e2d\u90e8\u652f\u90e8\u5b66\u8853\u96c6\u4f1a\uff08\u9759\u5ca1\uff092017\u5e745\u6708<\/p>\n\n\n\n

\u576a\u4e95 \u9999\u5948\u5b50, \u9ed2\u5d8b \u96c4\u5fd7, \u5409\u5ddd \u548c\u4eba, \u5bae\u8170 \u660c\u660e, \u4eca\u5f85 \u8ce2\u6cbb, \u79e6 \u6d69\u4fe1, \u4f50\u85e4 \u660e, \u5317\u5ddd\u5584\u653f:\u8840\u7ba1\u67c4\u4ed8\u304d\u904a\u96e2\u7d44\u7e54\u79fb\u690d\u306b\u3088\u308b\u53e3\u8154\u518d\u5efa\u75c7\u4f8b\u306e\u8853\u5f8c\u5408\u4f75\u75c7\u306b\u95a2\u3059\u308b\u691c\u8a0e. \u7b2c42\u56de\u65e5\u672c\u53e3\u8154\u5916\u79d1\u5b66\u4f1a\u4e2d\u90e8\u5730\u65b9\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08\u9759\u5ca1\uff092017\u5e745\u6708 \u30d7\u30ed\u30b0\u30e9\u30e0\u30fb\u6284\u9332\u96c6:41<\/p>\n\n\n\n

Hata H, Takada S, Yoshikawa K,\u3000Imamachi K, Edo M, Sagawa T, Rin S, Ueda M, Kitagawa Y:Analgesic Effects of Indomethacin Spray on Oral Mucositis in Patients Undergoing Chemotherapy. 2017Annual meeting MASCC (Washington DC), 2017.6<\/p>\n\n\n\n

\u6749\u5c71 \u6b63\u535a, \u53e4\u5ddd \u5eb7\u5e73, \u6bd4\u5609 \u76db\u654f, \u767e\u5408\u8349 \u5065\u572d\u5fd7\uff1a\u982d\u9838\u90e8\u764c\u5316\u5b66\u653e\u5c04\u7dda\u7642\u6cd5\u306b\u304a\u3051\u308b\u53e3\u8154\u885b\u751f\u72b6\u614b\u8a55\u4fa1\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1\u306e\u6709\u7528\u6027. \u7b2c41\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u4eac\u90fd\uff092017\u5e746\u6708 \u982d\u9838\u90e8\u764c\u5b66\u4f1a\u96d1\u8a8c43\u5dfb2\u53f7Page196(2017.05)<\/p>\n\n\n\n

\u4eca\u5f85 \u8ce2\u6cbb, \u576a\u4e95 \u9999\u5948\u5b50, \u9ed2\u5d8b \u96c4\u5fd7, \u5409\u5ddd \u548c\u4eba, \u5bae\u8170 \u660c\u660e, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u5f8c\u671f\u9ad8\u9f62\u8005\u53e3\u8154\u6241\u5e73\u4e0a\u76ae\u764c\u624b\u8853\u75c7\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c41\u56de\u65e5\u672c\u982d\u9838\u90e8\u764c\u5b66\u4f1a\uff08\u4eac\u90fd\uff092017\u5e746\u6708 \u982d\u9838\u90e8\u764c43\u5dfb2\u53f7 Page212(2017.05)<\/p>\n\n\n\n

\u6751\u7530 \u7ffc, \u6d45\u9999 \u5353\u54c9, \u4f50\u85e4 \u660e, \u5317\u5ddd \u5584\u653f\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u904e\u53bb10\u5e74\u9593\u306e\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u75c7\u4f8b\u306e\u81e8\u5e8a\u7684\u691c\u8a0e. \u7b2c19\u56de\u65e5\u672c\u53e3\u8154\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092017\u5e747\u6708<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u4e0b\u984e\u9aa8\u95a2\u7bc0\u7a81\u8d77\u9aa8\u6298\u306e\u81e8\u5e8a\u7684\u691c\u8a0e\uff08\uff11\uff09. \u7b2c19\u56de\u65e5\u672c\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092017\u5e747\u6708 \u6284\u9332P114<\/p>\n\n\n\n

\u9ad8\u91ce \u660c\u58eb, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u4f50\u85e4 \u5065\u5f66, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u5f53\u79d1\u306b\u304a\u3051\u308b\u4e0b\u984e\u9aa8\u95a2\u7bc0\u7a81\u8d77\u9aa8\u6298\u306e\u81e8\u5e8a\u7684\u691c\u8a0e\uff08\uff12\uff09\uff5e\u5916\u79d1\u7684\u6cbb\u7642\uff5e. \u7b2c19\u56de\u65e5\u672c\u984e\u9854\u9762\u5916\u50b7\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092017\u5e747\u6708 \u6284\u9332P115<\/p>\n\n\n\n

\u79e6 \u6d69\u4fe1, \u5c0f\u8c37 \u52dd, \u6c96\u6d25 \u6b63\u5c1a, \u698a\u539f \u5178\u5e78, \u9ce5\u8c37\u90e8 \u7d14\u884c, \u5409\u5ddd \u548c\u4eba, \u9580\u8107 \u7e41, \u5e73\u585a \u535a\u7fa9, \u6c38\u6613 \u88d5\u6a39, \u5317\u5ddd \u5584\u653f\uff1a\u5317\u6d77\u9053\u306b\u304a\u3051\u308b\u5168\u56fd\u304c\u3093\u8a3a\u7642\u533b\u79d1\u6b6f\u79d1\u9023\u643a\u63a8\u9032\u4e8b\u696d\u306e\u53d6\u308a\u7d44\u307f. \u7b2c70\u56de\u5317\u6d77\u9053\u6b6f\u79d1\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092017\u5e748\u6708<\/p>\n\n\n\n

\u548c\u7530 \u9ebb\u53cb\u7f8e, \u9ad8\u91ce \u660c\u58eb, \u4f50\u85e4 \u5065\u5f66, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u9f3b\u5185\u8996\u93e1\u3092\u4f75\u7528\u3057\u3066\u6cbb\u7642\u3092\u884c\u3063\u305f\u4e0a\u984eBRONJ\u306e1\u4f8b. \u7b2c27\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c30\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092017\u5e749\u6708 \u6284\u9332P122<\/p>\n\n\n\n

\u4f50\u85e4 \u5065\u5f66, \u548c\u7530 \u9ebb\u53cb\u7f8e, \u9ad8\u91ce \u660c\u58eb, \u7267\u91ce \u4fee\u6cbb\u90ce\uff1a\u8840\u7ba1\u65b0\u751f\u963b\u5bb3\u5264\u30e9\u30e0\u30b7\u30eb\u30de\u30d6\u306e\u95a2\u4e0e\u304c\u7591\u308f\u308c\u305fMRONJ(medication-related osteonecrosis of the jaw)\u306e1\u4f8b. \u7b2c27\u56de\u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c30\u56de\u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff092017\u5e749\u6708 \u6284\u9332P123<\/p>\n\n\n\n

\u592a\u5b50 \u82b3\u4ec1\uff0c\u6c34\u8d8a \u5b5d\u5178\uff0c\u64ad\u78e8 \u7f8e\u6a39\uff0c\u5317\u5ddd \u5584\u653f\uff1a\u53e3\u84cb\u306b\u767a\u75c7\u3057\u305f\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u95a2\u9023\u30ea\u30f3\u30d1\u5897\u6b96\u6027\u75be\u60a3\u306e1\u4f8b\uff0e\u7b2c27\u56de \u65e5\u672c\u53e3\u8154\u5185\u79d1\u5b66\u4f1a\u30fb\u7b2c30\u56de \u65e5\u672c\u53e3\u8154\u8a3a\u65ad\u5b66\u4f1a\u5408\u540c\u5b66\u8853\u5927\u4f1a\uff08\u672d\u5e4c\uff09 2017\u5e749\u6708<\/p>\n\n\n\n

Kamaguchi M, Iwata H, Mori Y, Ujiie H, Kitagawa Y, Shimizu H : High-dose immunoglobulin contains anti-idiotypic antibodies against BP-IgG. 47th Annual ESDR Meeting (Salzburg), 2017.9 Journal of Investigative Dermatology, S243<\/p>\n","protected":false},"excerpt":{"rendered":"

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