{"id":120,"date":"2024-02-20T16:56:59","date_gmt":"2024-02-20T07:56:59","guid":{"rendered":"https:\/\/www.den.hokudai.ac.jp\/?post_type=department_post&#038;p=120"},"modified":"2026-04-01T16:32:58","modified_gmt":"2026-04-01T07:32:58","slug":"oral-biochemistry-and-molecular-biology","status":"publish","type":"department_post","link":"https:\/\/www.den.hokudai.ac.jp\/en\/research\/oral-biochemistry-and-molecular-biology","title":{"rendered":"Biochemistry  (JP)"},"content":{"rendered":"\n<h4 class=\"wp-block-heading has-text-align-center is-style-sideline\">\u3053\u306e\u6559\u5ba4\u306b\u95a2\u9023\u3059\u308b\u30ef\u30fc\u30c9<\/h4>\n\n\n\n<ul class=\"wp-block-list is-style-word\">\n<li>\u9aa8\u4ee3\u8b1d<\/li>\n\n\n\n<li>\u7d30\u80de\u751f\u7269\u5b66<\/li>\n\n\n\n<li>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc<\/li>\n\n\n\n<li>\u30b2\u30ce\u30e0\u533b\u5b66<\/li>\n\n\n\n<li>\u6b6f\u5468\u75c5<\/li>\n\n\n\n<li>\u8840\u7ba1\u5f62\u6210<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/www.den.hokudai.ac.jp\/en\/wp-content\/uploads\/sites\/3\/2024\/02\/40c7029861313914ad02829e9e987f02.png\"><img loading=\"lazy\" decoding=\"async\" width=\"1305\" height=\"636\" data-id=\"2757\" src=\"https:\/\/www.den.hokudai.ac.jp\/en\/wp-content\/uploads\/sites\/3\/2024\/02\/40c7029861313914ad02829e9e987f02.png\" alt=\"\" class=\"wp-image-2757\" srcset=\"https:\/\/www.den.hokudai.ac.jp\/en\/wp-content\/uploads\/sites\/3\/2024\/02\/40c7029861313914ad02829e9e987f02.png 1305w, https:\/\/www.den.hokudai.ac.jp\/en\/wp-content\/uploads\/sites\/3\/2024\/02\/40c7029861313914ad02829e9e987f02-800x390.png 800w, https:\/\/www.den.hokudai.ac.jp\/en\/wp-content\/uploads\/sites\/3\/2024\/02\/40c7029861313914ad02829e9e987f02-768x374.png 768w\" sizes=\"auto, (max-width: 1305px) 100vw, 1305px\" \/><\/a><\/figure>\n<\/figure>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<p>\u5206\u5b50\u751f\u5316\u5b66\u306f\u3001\u751f\u4f53\u5185\u306e\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u306e\u6a5f\u80fd\u3092\u89e3\u660e\u3057\u3001\u75be\u60a3\u306e\u767a\u75c7\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u5b66\u554f\u5206\u91ce\u3067\u3059\u3002\u672c\u6559\u5ba4\u3067\u306f\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u6a5f\u80fd\u3001\u4ee3\u8b1d\u7d4c\u8def\u306e\u7406\u89e3\u3092\u6df1\u3081\u308b\u3053\u3068\u3067\u3001\u75c5\u614b\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u63a2\u6c42\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u751f\u5316\u5b66\u7684\u8996\u70b9\u304b\u3089\u591a\u69d8\u306a\u75be\u60a3\u3092\u7814\u7a76\u3057\u3001\u57fa\u790e\u7814\u7a76\u3068\u81e8\u5e8a\u5fdc\u7528\u3092\u3064\u306a\u3050\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>1.<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-theme-azure-color\"><strong>\u9aa8\u7c97\u9b06\u75c7\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u95a2\u4e0e\u3059\u308b\u591a\u767a\u6027\u907a\u4f1d\u5b50\uff08pleiotropic gene\uff09\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u89e3\u660e<\/strong><\/mark><\/strong><br>\u8fd1\u5e74\u3001\u9aa8\u7c97\u9b06\u75c7\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u304c\u5171\u901a\u306e\u907a\u4f1d\u7684\u8981\u56e0\u3092\u6301\u3064\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u7279\u5b9a\u306e\u591a\u767a\u6027\u907a\u4f1d\u5b50\uff08pleiotropic gene\uff09\u306f\u3001\u9aa8\u4ee3\u8b1d\u3068\u795e\u7d4c\u5909\u6027\u306e\u4e21\u65b9\u306b\u95a2\u4e0e\u3057\u3001\u305d\u306e\u767a\u73fe\u7570\u5e38\u304c\u75be\u60a3\u306e\u9032\u884c\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u6559\u5ba4\u3067\u306f\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\u3084\u5206\u5b50\u751f\u7269\u5b66\u7684\u624b\u6cd5\u3092\u99c6\u4f7f\u3057\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u304c\u75be\u60a3\u767a\u75c7\u306b\u3069\u306e\u3088\u3046\u306b\u95a2\u4e0e\u3059\u308b\u306e\u304b\u3092\u89e3\u660e\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u30022.<\/p>\n\n\n\n<p>2.<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-theme-azure-color\"><strong><strong>\u6162\u6027\u6b6f\u5468\u708e\u306e\u4e3b\u8981\u539f\u56e0\u83cc <em>Porphyromonas gingivalis<\/em> \u306b\u95a2\u9023\u3059\u308b\u708e\u75c7\u53cd\u5fdc\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u9032\u884c\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u7814\u7a76<\/strong><\/strong><\/mark><\/strong><br>\u6b6f\u5468\u75c5\u306e\u4e3b\u306a\u539f\u56e0\u83cc\u3067\u3042\u308b <em>Porphyromonas gingivalis<\/em> \u306f\u3001\u6162\u6027\u7684\u306a\u708e\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u5168\u8eab\u75be\u60a3\u3068\u306e\u95a2\u9023\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u8fd1\u5e74\u3001<em>P. gingivalis<\/em> \u304c\u8133\u5185\u3078\u79fb\u884c\u3057\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u75c5\u614b\u5f62\u6210\u306b\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u708e\u75c7\u5fdc\u7b54\u3092\u4e2d\u5fc3\u306b\u3001\u6b6f\u5468\u708e\u304c\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u767a\u75c7\u30fb\u9032\u884c\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u89e3\u660e\u3057\u3001\u65b0\u305f\u306a\u6cbb\u7642\u6226\u7565\u306e\u69cb\u7bc9\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>3.<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-theme-azure-color\"><strong>AI\u3092\u6d3b\u7528\u3057\u305f\u65b0\u85ac\u958b\u767a\u304a\u3088\u3073\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u89e3\u6790\u306e\u5c0e\u5165<\/strong><\/mark><\/strong><br>\u672c\u6559\u5ba4\u3067\u306f\u3001\u4eba\u5de5\u77e5\u80fd\uff08AI\uff09\u3092\u6d3b\u7528\u3057\u305f\u5275\u85ac\u7814\u7a76\u3068\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u89e3\u6790\u3092\u63a8\u9032\u3057\u3066\u3044\u307e\u3059\u3002\u5927\u898f\u6a21\u306a\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u3084\u30d7\u30ed\u30c6\u30aa\u30df\u30af\u30b9\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u7684\u306b\u89e3\u6790\u3057\u3001\u75be\u60a3\u306b\u95a2\u9023\u3059\u308b\u65b0\u898f\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u767a\u898b\u3084\u5275\u85ac\u30bf\u30fc\u30b2\u30c3\u30c8\u306e\u7279\u5b9a\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001AI\u3092\u57fa\u76e4\u3068\u3057\u305f\u30bf\u30fc\u30b2\u30c3\u30c8\u5206\u5b50\u69cb\u9020\u89e3\u6790\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u75be\u60a3\u6cbb\u7642\u306b\u6709\u671b\u306a\u65b0\u85ac\u5019\u88dc\u306e\u63a2\u7d22\u3092\u52a0\u901f\u3057\u3001\u500b\u5225\u5316\u533b\u7642\u306e\u5b9f\u73fe\u306b\u5411\u3051\u305f\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>4.<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-theme-azure-color\"><strong>\u7d44\u7e54\u518d\u751f\u306e\u305f\u3081\u306e\u8840\u7ba1\u5f62\u6210\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e<\/strong><\/mark><\/strong><br>\u672c\u7814\u7a76\u3067\u306f\u3001\u8840\u7ba1\u65b0\u751f\u3092\u5236\u5fa1\u3059\u308b\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u660e\u3089\u304b\u306b\u3057\u3001\u7279\u306b\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306e\u5897\u6b96\u3084\u904a\u8d70\u3001\u8840\u7ba1\u7db2\u306e\u5f62\u6210\u306b\u95a2\u4e0e\u3059\u308b\u30b7\u30b0\u30ca\u30eb\u7d4c\u8def\u3092\u89e3\u6790\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u6210\u9577\u56e0\u5b50\u3084\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u5f71\u97ff\u3092\u8abf\u3079\u3001\u52b9\u679c\u7684\u306a\u8840\u7ba1\u518d\u751f\u3092\u8a98\u5c0e\u3059\u308b\u56e0\u5b50\u306e\u7279\u5b9a\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5275\u50b7\u6cbb\u7652\u3084\u6b6f\u5468\u7d44\u7e54\u518d\u751f\u3001\u9aa8\u518d\u751f\u306a\u3069\u306e\u518d\u751f\u533b\u7642\u3078\u306e\u5fdc\u7528\u3092\u8996\u91ce\u306b\u5165\u308c\u305f\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7814\u7a76\u3092\u901a\u3058\u3066\u3001\u53e3\u8154\u9818\u57df\u3068\u5168\u8eab\u75be\u60a3\u306e\u95a2\u9023\u3092\u660e\u3089\u304b\u306b\u3057\u3001\u65b0\u305f\u306a\u6cbb\u7642\u6226\u7565\u306e\u958b\u767a\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u3092\u76ee\u6a19\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u6559\u5ba4\u3067\u306f\u3001\u57fa\u790e\u7814\u7a76\u3068\u81e8\u5e8a\u5fdc\u7528\u3092\u7d50\u3073\u3064\u3051\u308b\u5b66\u969b\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u91cd\u8996\u3057\u3001\u672a\u6765\u306e\u533b\u7642\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading is-style-sideline\" style=\"margin-top:var(--wp--preset--spacing--50)\">\u62c5\u5f53\u6559\u54e1<\/h4>\n\n\n<p class=\"faculty pc_center\">Ji-Won Lee<\/p>\n<!-- \/\/ PART: DEPARTMENT_FACULTY -->\n\n\n\n<div class=\"wp-block-buttons is-style-linkbutton is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-d234f690 wp-block-buttons-is-layout-flex\" style=\"margin-top:var(--wp--preset--spacing--50);margin-bottom:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.den.hokudai.ac.jp\/biochem\/\" target=\"_blank\" rel=\"noreferrer noopener\">Biochemistry 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