• Related Key Words:
  • Tissue remodeling
  • Stomatognathic function
  • Orthodontic materials
  • Jaw deformity
  • Cleft lip and palate
  • Congenital anomaly
  • Face appearance
  • Aesthetic assessment

(1) Tissue remodeling: We are studying the mechanism of tissue remodeling induced by mechanical stimulation and the effect of aging on the tissue remodeling mechanism. We are also conducting biochemical research using cultured cells, research on the microvasculature, and histological research using diabetic rats.

(2) Stomatognathic function: The tongue, lips, and cheeks play important roles in stomatognathic functions such as pronunciation, chewing, and swallowing. Using a lip-contact sensor and electrical recording device for estimating the sealed lip ratio, we are conducting basic research and clinical research on the diagnosis and treatment of stomatognathic dysfunctions and myofunctional therapy (MFT).

(3) Orthodontic materials: We are developing esthetic orthodontic wires with a fiber-reinforced plastic (FRP) structure and novel conceptive nano-composite materials such as orthodontic adhesives and orthodontic implants.

(4) Jaw deformity: We are trying to elucidate the cause of craniofacial growth abnormality and are conducting basic and clinical studies on diagnosis and methods of surgical orthodontic treatment. To identify the susceptibility loci of mandibular prognathism, we are carrying out a GWAS using a microsatellite in Japanese subjects. In addition, we are investigating the mechanism of malocclusion using mice that spontaneously develop malocclusion.

(5) Cleft lip and palate: We are conducting clinical research in patients with cleft lip and/or palate or other congenital anomalies.

(6) Research on facial morphology and smile